Composition #1: Nishioka, T., Watanabe, J., Kawabata, J., Niki, R. Isolation and activity of N-p-coumaroyltyramine, an alpha-glucosidase inhibitor in Welsh onion (Allium fistulosum). BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1997, vol. 61, no. 7, p. 1138–1141. .
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Plant part:
Bulb / clove (as part-nature) (A067A)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
MeOH
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Substance:
N-P-Coumaroyltyramine N-P-Coumaroyltyramine (RF-00010849-PAR)
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
N-p-Coumaroyltyramine
Endpoint study
#1: Nishioka, T., Watanabe, J., Kawabata, J., Niki, R. Isolation and activity of N-p-coumaroyltyramine, an alpha-glucosidase inhibitor in Welsh onion (Allium fistulosum). BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1997, vol. 61, no. 7, p. 1138–1141. .
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Study relevance:
Human health
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Substance:
N-P-Coumaroyltyramine N-P-Coumaroyltyramine (RF-00010849-PAR)
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Type of toxicological test:
in vitro (CHD061TT)
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Endpoint measured:
Enzyme inhibition (CHD067EP)
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Concentration unit:
Millimole (G115A)
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Effect concentration:
2400
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Critical effect:
Digestive (TOX18A)
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Target tissue:
Digestive (TT002A)
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Effect description:
85% alpha-glucosidase inhibition
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Effect or parameter linked to the endpoint:
enzyme inhibition (CHD032BE)
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Internal remarks:
alpha-glucosidase inhibition
