Endpoint study
#1: Gibson, J. A., O'Sullivan, B. M. Lung lesions in horses fed mist flower (Eupatorium riparium). Australian veterinary journal, 1984, vol. 61, no. 8, p. 271–None. .
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Study relevance:
Animal (target species) health
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Plant part:
Live plants (as part-nature) (A0BA0)
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Type of toxicological test:
subchronic (CHD013TT)
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Tested organism:
Horse (as animal) (A0B9Z)
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Route of exposure:
ORAL: FEED (OECD2230PL)
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Unit of exposure duration:
Month (G206A)
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Number of organisms dosed:
2
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Control groups used:
no data
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Endpoint measured:
Dose level (CHD014EP)
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Concentration unit:
Kilograms per day (G239A)
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Effect concentration:
1.5
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Critical effect:
PULMONARY AND CARDIAC (TOX08A)
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Target tissue:
respiratory: Lung (TT041A)
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Effect description:
eosinophilic bronchiolitis, Lesions immediately under the visceral pleura had a plumred, depressed surface
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Effect or parameter linked to the endpoint:
other (CHD003BE)
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Internal remarks:
Lesions immediately under the visceral pleura had a plumred, depressed surface.Microscopically an eosinophilic bronchiolitis.
