EFSA Compendium of Botanicals

Draft - work in progress

Acalypha hispida Burm.f.

Family:: Euphorbiaceae
Approval state:: Approved
Number of articles retrieved:: 53
Number of processed references:: 4

Compositions

#1: alkaloids #2: Saponins #3: Cardenolides #4: Tannins #5: Labdanes diterpenes, 15,16-epoxylabda-13(16),14dien-8-alpha-ol #6: hydroxylanthraquinones #7: Alkaloids - detected by Hager’s Test and Wagner’s Test #8: Cardiac glycosides - detected by Legal Test + Keller-killiani Test

Endpoint Studies

Genotoxicity

Composition #1: Soladoye, Mike O., Sonibare, Mubo A., Rosanwo, Temitope O. Phytochemical and morphometric analysis of the genus Acalypha Linn. (Euphorbiaceae).. Journal of Applied Sciences, 2008, vol. 8, no. 17, p. 3044–3049. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Unspecified
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

alkaloids

Composition #2: Soladoye, Mike O., Sonibare, Mubo A., Rosanwo, Temitope O. Phytochemical and morphometric analysis of the genus Acalypha Linn. (Euphorbiaceae).. Journal of Applied Sciences, 2008, vol. 8, no. 17, p. 3044–3049. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Saponins

Composition #3: Soladoye, Mike O., Sonibare, Mubo A., Rosanwo, Temitope O. Phytochemical and morphometric analysis of the genus Acalypha Linn. (Euphorbiaceae).. Journal of Applied Sciences, 2008, vol. 8, no. 17, p. 3044–3049. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Unspecified
Substance:

cardenolides (RF-00004389-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Cardenolides

Composition #4: Soladoye, Mike O., Sonibare, Mubo A., Rosanwo, Temitope O. Phytochemical and morphometric analysis of the genus Acalypha Linn. (Euphorbiaceae).. Journal of Applied Sciences, 2008, vol. 8, no. 17, p. 3044–3049. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins

Composition #5: Onocha, P. A., Oloyede, G. K., Bamkole, O. A. Volatile oil composition, cytotoxicity and free radical scavenging activity of the leaves and twigs of the chenille plant (Acalypha hispida).. International Journal of Essential Oil Therapeutics, 2010, vol. 4, no. 3-4, p. 86-89.

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Distillation
Substance:

labdane diterpenes (RF-00004392-PAR)
Additional substance description:

15,16-epoxylabda-13(16),14dien-8-alpha-ol
Analytical method code:

GC-MS (F046A)
Result unit:

Percent Area (G139A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

12.75
Internal remarks:

Labdanes diterpenes, 15,16-epoxylabda-13(16),14dien-8-alpha-ol

Composition #6: Iniaghe, O.M., Malomo, S.O., Adebayo, J.O. Proximate composition and phytochemical constituents of leaves of some Acalypha species. Pakistan Journal of Nutrition, 2009, vol. 8, no. 3, p. 256–258. DOI: 10.3923/pjn.2009.256.258. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Water + Methanol extracs
Substance:

1,8-dihydroxyanthraquinone derivatives (RF-00004312-PAR)
Additional substance description:

Hydroxylanthraquinones
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

hydroxylanthraquinones

Composition #7: Manikanta, B., Varma, P.R., Krishna, V., Kumar, A.R., Rathinam, K.M.S. Phytochemical evaluation of Acalypha hispida, Acalypha nervosa and Acalypha fruiticosa. Journal of Chemical and Pharmaceutical Sciences, 2014, vol. 7, no. 3, p. 197–199. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol + water extract
Substance:

Alkaloids (RF-00004360-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids - detected by Hager’s Test and Wagner’s Test

Composition #8: Manikanta, B., Varma, P.R., Krishna, V., Kumar, A.R., Rathinam, K.M.S. Phytochemical evaluation of Acalypha hispida, Acalypha nervosa and Acalypha fruiticosa. Journal of Chemical and Pharmaceutical Sciences, 2014, vol. 7, no. 3, p. 197–199. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol extract + water extracts
Substance:

cardiac glycosides (RF-00010823-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Cardiac glycosides - detected by Legal Test + Keller-killiani Test