Draft - work in progress
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- Acacia sinuata (Lour.) Merr.
Acacia sinuata (Lour.) Merr.
- Family:
- Fabaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 36
- Number of processed references:
- 2
Composition #1: Ramya, Krishna P. S., Lavanya, Bhaduri., Sireesha, Pulla., Nagarjuna, S., Reddy, Y. Padmanabha. Comparative study of Acacia nilotica and Acacia sinuata for diuretic activity.. pharmacia sinica, 2011, vol. 2, no. 6, p. 17–22. .
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Plant part:
Fruit unspecified (as part-nature) (A067D)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
methanol, ethanol
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Substance:
Alkaloids (RF-00004360-PAR)
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Additional substance description:
in pods
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Analytical method code:
Phytochemical screening (F604A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Alkaloids in pods
Composition #2: Ramya, Krishna P. S., Lavanya, Bhaduri., Sireesha, Pulla., Nagarjuna, S., Reddy, Y. Padmanabha. Comparative study of Acacia nilotica and Acacia sinuata for diuretic activity.. pharmacia sinica, 2011, vol. 2, no. 6, p. 17–22. .
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Plant part:
Fruit unspecified (as part-nature) (A067D)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
methanol, ethanol
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Substance:
Saponins (RF-00004333-PAR)
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Additional substance description:
in pods
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Analytical method code:
Phytochemical screening (F604A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Saponins in pods
Composition #3: Ramya, Krishna P. S., Lavanya, Bhaduri., Sireesha, Pulla., Nagarjuna, S., Reddy, Y. Padmanabha. Comparative study of Acacia nilotica and Acacia sinuata for diuretic activity.. pharmacia sinica, 2011, vol. 2, no. 6, p. 17–22. .
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-
Plant part:
Fruit unspecified (as part-nature) (A067D)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
ethanol and methanol
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Substance:
Tannins (RF-00004337-PAR)
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Additional substance description:
in pods
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Analytical method code:
Phytochemical screening (F604A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Tannins in pods
Composition #4: Savithramma, N., Rao, M. Linga., Ankanna, S. Phytochemical screening of traditional medicinal plants.. journal of pharmacy research, 2011, vol. 4, no. 10, p. 3414–3416. .
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
water
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Substance:
Saponins (RF-00004333-PAR)
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Analytical method code:
Phytochemical screening (F604A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Saponins in leaves
Endpoint study
#1: Ramya, Krishna P. S., Lavanya, Bhaduri., Sireesha, Pulla., Nagarjuna, S., Reddy, Y. Padmanabha. Comparative study of Acacia nilotica and Acacia sinuata for diuretic activity.. pharmacia sinica, 2011, vol. 2, no. 6, p. 17–22. .
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Study relevance:
Human health
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Plant part:
Fruit unspecified (as part-nature) (A067D)
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Preparation/Extraction method:
Solvent extraction (A0BZR)
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Additional plant/substance description:
ethanol and methanol from pods
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Type of toxicological test:
other (CHD008TT)
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Limit test:
Not applicable
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Tested organism:
Rat (as animal) (A0CNV)
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Strain of test organism:
Wistar (CHD013ST)
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Route of exposure:
ORAL: UNSPECIFIED (OECD2234PL)
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Endpoint measured:
Dose level (CHD014EP)
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Concentration unit:
Milligram/kilogram (G061A)
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Effect concentration:
300
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Critical effect:
NEPHROTOXICITY (TOX03A)
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Target tissue:
urogenital: Kidneys (TT046A)
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Effect description:
Ethanolic extract showed significant increase in urine volume and concentrations of Na+ ,K+ ,Cl-
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Effect or parameter linked to the endpoint:
urinalysis (CHD029BE)
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Internal remarks:
The ethanolic and methanolic extracts of pods in increased diuresis in Wistar rats.
