Draft - work in progress
-
- Carica Papaya peels
Carica Papaya peels
- Family:
- None
- Approval state:
- Under evaluation
- Number of articles retrieved:
- 0
- Number of processed references:
- 13
Compositions
#1: determined according to Velderrain-Rodríguez et al. (2018) in a diode array detector ultra-resolution liquid chromatography system (UPLC-DAD; ACQUITY, Waters Corp., Milford, MA, USA).
#2: determined according to Velderrain-Rodríguez et al. (2018) in a diode array detector ultra-resolution liquid chromatography system (UPLC-DAD; ACQUITY, Waters Corp., Milford, MA, USA).
#3:
#4:
#5:
#6:
#7:
#8:
#9:
#10:
#11: (13Z)-violaxanthin or (all-E)-violaxanthin (μg/100 g fresh weight ± standard deviation)
#12: lutein-5,6-epoxide (μg/100 g fresh weight ± standard deviation)
#13: Substance from papaya latex
#14: determined titrimetrically by using the method described by Olumuyiwa et al. (2003).
#15: the cyanide content (HCN) in mg/kg was calculated using the formula:
HCN (mg/kg) = (100/W) × Au (As)
where,
W = Weight of sample analysed (g)
Au = Absorbance of sample (nm)
As = Absorbance of the standard HCN solution (nm).
#16: 6’’-O-Malonylgenistin by LC-ESI-QTOF-MS/MS
#17: 6’’-O-Malonylglycitin by LC-ESI-QTOF-MS/MS
#18: Glycitin by LC-ESI-QTOF-MS/MS
#19: 6’’-O-Malonyldaidzin by LC-ESI-QTOF-MS/MS
#20: (+)-Gallocatechin 3-O-gallate by LC-ESI-QTOF-MS/MS
#21: (+)-Gallocatechin by LC-ESI-QTOF-MS/MS
#22: Gallic acid by LC-ESI-QTOF-MS/MS
#23: Esculetin by LC-ESI-QTOF-MS/MS
#24: Isopimpinellin by LC-ESI-QTOF-MS/MS
#25: Lignans by LC-ESI-QTOF-MS/MS
#26: Schisandrin C by LC-ESI-QTOF-MS/MS
#27: Isoflavonoids by LC-ESI-QTOF-MS/MS
#28: Hydroxycoumarins by LC-ESI-QTOF-MS/MS
#29: Stilbenes by LC-ESI-QTOF-MS/MS
Composition #1: Molina, Ofelia Marquez., Dominguez-Avila, Jesus Abraham., Pareek, Sunil., Santana, Tomas Jesus Madera., Aguilar, Gustavo Adolfo Gonzalez., Lopez-Martinez, Leticia Xochitl. Valorization of tropical fruit peel powders: Physico‐ chemical composition, techno‐functional properties, and in vitro antioxidant and antidiabetic activities. emirates journal of food and agriculture, 2023, vol. 35, no. 6, p. 577–587. DOI: 10.9755/ejfa.2023.v35.i6.3105.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Substance:
p-coumaric acid (RF-00010717-PAR)
-
Analytical method code:
Chromatographic tests (F015A)
-
Result unit:
Microgram/gram (G049A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
533.98
-
Internal remarks:
determined according to Velderrain-Rodríguez et al. (2018) in a diode array detector ultra-resolution liquid chromatography system (UPLC-DAD; ACQUITY, Waters Corp., Milford, MA, USA).
Composition #2: Molina, Ofelia Marquez., Dominguez-Avila, Jesus Abraham., Pareek, Sunil., Santana, Tomas Jesus Madera., Aguilar, Gustavo Adolfo Gonzalez., Lopez-Martinez, Leticia Xochitl. Valorization of tropical fruit peel powders: Physico‐ chemical composition, techno‐functional properties, and in vitro antioxidant and antidiabetic activities. emirates journal of food and agriculture, 2023, vol. 35, no. 6, p. 577–587. DOI: 10.9755/ejfa.2023.v35.i6.3105.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Substance:
gallic acid (RF-00003821-PAR)
-
Analytical method code:
Chromatographic tests (F015A)
-
Result unit:
Microgram/gram (G049A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
317.22
-
Internal remarks:
determined according to Velderrain-Rodríguez et al. (2018) in a diode array detector ultra-resolution liquid chromatography system (UPLC-DAD; ACQUITY, Waters Corp., Milford, MA, USA).
Composition #3: Edori, O. S., Nwineewii, J. D., Nwoke, I. B. METALS AND PHYTOCHEMICAL COMPOSITION OF LEAVES AND PEELS OF PAWPAW (Carica papaya) SOLD WITHIN PORT HARCOURT, RIVERS STATE, NIGERIA. pharmacophore, 2019, vol. 10, no. 4, p. 57–61. .
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
extraction of dried peels
-
Substance:
Quinones (RF-00010832-PAR)
-
Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
Composition #4: Edori, O. S., Nwineewii, J. D., Nwoke, I. B. METALS AND PHYTOCHEMICAL COMPOSITION OF LEAVES AND PEELS OF PAWPAW (Carica papaya) SOLD WITHIN PORT HARCOURT, RIVERS STATE, NIGERIA. pharmacophore, 2019, vol. 10, no. 4, p. 57–61. .
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
extraction of dried peels
-
Substance:
Alkaloids (RF-00004360-PAR)
-
Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
Composition #5: Edori, O. S., Nwineewii, J. D., Nwoke, I. B. METALS AND PHYTOCHEMICAL COMPOSITION OF LEAVES AND PEELS OF PAWPAW (Carica papaya) SOLD WITHIN PORT HARCOURT, RIVERS STATE, NIGERIA. pharmacophore, 2019, vol. 10, no. 4, p. 57–61. .
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
extraction of dried peels
-
Substance:
Tannins (RF-00004337-PAR)
-
Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
Composition #6: Khan, Asna., Zahiruddin, Sultan., Ibrahim, Mohammad., Basist, Parakh., Gaurav., Parveen, Rabea., Umar, Shahid., Ahmad, Sayeed. Thin Layer Chromatography‐Mass Spectrometry Bioautographic Identification of Free Radical Scavenging Compounds and Metabolomic Profile of Carica papaya Linn. Fruit and Seeds using High‐Performance Thin‐Layer Chromatography, Gas Chromatography‐Mass Spectrometry and Ultra‐Performance Liquid Chromatography‐Mass Spectrometry. pharmacognosy magazine, 2021, vol. 17, no. 5, p. S21–S28. DOI: 10.4103/pm.pm_326_20.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
extraction of dried material
-
Substance:
Chlorogenic acid (RF-00010714-PAR)
-
Analytical method code:
Mass Spectroscopy and hyphenated methods without chromatography (F063A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
Composition #7: Khan, Asna., Zahiruddin, Sultan., Ibrahim, Mohammad., Basist, Parakh., Gaurav., Parveen, Rabea., Umar, Shahid., Ahmad, Sayeed. Thin Layer Chromatography‐Mass Spectrometry Bioautographic Identification of Free Radical Scavenging Compounds and Metabolomic Profile of Carica papaya Linn. Fruit and Seeds using High‐Performance Thin‐Layer Chromatography, Gas Chromatography‐Mass Spectrometry and Ultra‐Performance Liquid Chromatography‐Mass Spectrometry. pharmacognosy magazine, 2021, vol. 17, no. 5, p. S21–S28. DOI: 10.4103/pm.pm_326_20.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
extraction of dried material
-
Substance:
gallic acid (RF-00003821-PAR)
-
Analytical method code:
Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
-
Result unit:
Percent (G138A)
-
Result expression:
Whole weight (B001A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
0.33
Composition #8: Rivera-Pastrana, D. M., Yahia, E. M., Gonzalez-Aguilar, G. A. Identification of Phenolic and Carotenoid Compounds in Carica papaya L. 'Maradol' Using Liquid Chromatography ‐ Mass Spectrometry. vi international postharvest symposium, 2010, vol. 877, p. 1197–1204. .
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Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Substance:
gallic acid (RF-00003821-PAR)
-
Analytical method code:
HPLC-ESI-MS (F033A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
Composition #9: Rivera-Pastrana, D. M., Yahia, E. M., Gonzalez-Aguilar, G. A. Identification of Phenolic and Carotenoid Compounds in Carica papaya L. 'Maradol' Using Liquid Chromatography ‐ Mass Spectrometry. vi international postharvest symposium, 2010, vol. 877, p. 1197–1204. .
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Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Substance:
3,4-Dihydroxybenzoic acid (RF-00008853-PAR)
-
Analytical method code:
HPLC-ESI-MS (F033A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
Composition #10: Nieto Calvache, Jhon., Cueto, Mario., Farroni, Abel., de Escalada Pla, Marina., Noemi Gerschenson, Lia. Antioxidant characterization of new dietary fiber concentrates from papaya pulp and peel (Carica papaya L.). journal of functional foods, 2016, vol. 27, p. 319–328. DOI: 10.1016/j.jff.2016.09.012.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
drying
-
Substance:
3,4-Dihydroxybenzoic acid (RF-00008853-PAR)
-
Analytical method code:
HPLC-MS/MS (F698A)
-
Analytical method - additional description:
high-performance liquid chromatography-mass spectrometry
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
Composition #11: Lara-Abia, Sara., Lobo-Rodrigo, Gloria., Welti-Chanes, Jorge., Pilar Cano, M. Carotenoid and Carotenoid Ester Profile and Their Deposition in Plastids in Fruits of New Papaya (Carica papaya L.) Varieties from the Canary Islands. foods, 2021, vol. 10, no. 2 . DOI: 10.3390/foods10020434.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Additional extraction description:
chromatographic elution, UV/visible data, and mass spectral characteristics
-
Substance:
Violaxanthin (RF-00013331-PAR)
-
Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
-
Result unit:
Microgram/100 gram (G046A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
24 - 441.4
-
Internal remarks:
(13Z)-violaxanthin or (all-E)-violaxanthin (μg/100 g fresh weight ± standard deviation)
Composition #12: Lara-Abia, Sara., Lobo-Rodrigo, Gloria., Welti-Chanes, Jorge., Pilar Cano, M. Carotenoid and Carotenoid Ester Profile and Their Deposition in Plastids in Fruits of New Papaya (Carica papaya L.) Varieties from the Canary Islands. foods, 2021, vol. 10, no. 2 . DOI: 10.3390/foods10020434.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Substance:
Lutein epoxide (RF-00011263-PAR)
-
Additional substance description:
lutein-5,6-epoxide
-
Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
-
Result unit:
Microgram/100 gram (G046A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
< 273.5
-
Internal remarks:
lutein-5,6-epoxide (μg/100 g fresh weight ± standard deviation)
Composition #13: TOPHAM, CM., SALIH, E., FRAZAO, C., KOWLESSUR, D., OVERINGTON, JP., THOMAS, M., BROCKLEHURST, SM., PATEL, M., THOMAS, EW., BROCKLEHURST, K. STRUCTURE‐FUNCTION‐RELATIONSHIPS IN THE CYSTEINE PROTEINASES ACTINIDIN, PAPAIN AND PAPAYA PROTEINASE‐OMEGA ‐ 3‐DIMENSIONAL STRUCTURE OF PAPAYA PROTEINASE‐OMEGA DEDUCED BY KNOWLEDGE‐BASED MODELING AND ACTIVE‐CENTER CHARACTERISTICS DETERMINED BY 2‐HYDRONIC‐STATE REACTIVITY PROBE KINETICS AND KINETICS OF CATALYSIS. biochemical journal, 1991, vol. 280, p. 79–92. DOI: 10.1042/bj2800079.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Additional extraction description:
covalent chromatography according to Brocklehurst, K., Baines, B. S. & Malthouse, J. P. G. (1981) Biochem. J. 197, 739-746
-
Substance:
Actinidine (RF-00004129-PAR)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Substance from papaya latex
Composition #14: Onyenweaku, Eridiong O., Kesa, Hema. Micronutrient and antinutrient content of semi‐processed fruit peels: Towards boosting immunity. health sa gesondheid, 2024, vol. 29 . DOI: 10.4102/hsag.v29i0.2682.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Substance:
Oxalates (RF-00004308-PAR)
-
Analytical method code:
Distillation-titrimetry (modified Monier-William method) (F682A)
-
Result unit:
Milligram/100 gram (G057A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
0.53
-
Internal remarks:
determined titrimetrically by using the method described by Olumuyiwa et al. (2003).
Composition #15: Onyenweaku, Eridiong O., Kesa, Hema. Micronutrient and antinutrient content of semi‐processed fruit peels: Towards boosting immunity. health sa gesondheid, 2024, vol. 29 . DOI: 10.4102/hsag.v29i0.2682.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Substance:
Hydrogen cyanide (cyanides expressed as hydrogen cyanide) (RF-0243-001-PPP)
-
Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
-
Result unit:
Milligram/100 gram (G057A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
18.72
-
Internal remarks:
the cyanide content (HCN) in mg/kg was calculated using the formula:
HCN (mg/kg) = (100/W) × Au (As)
where,
W = Weight of sample analysed (g)
Au = Absorbance of sample (nm)
As = Absorbance of the standard HCN solution (nm).
Composition #16: Zhou, Yufeng., Cao, Yuanxiao., Li, Jiaxun., Agar, Osman Tuncay., Barrow, Colin., Dunshea, Frank., Suleria, Hafiz A. R. Screening and characterization of phenolic compounds by LC‐ESI‐QTOF‐MS/MS and their antioxidant potentials in papaya fruit and their by‐products activities. food bioscience, 2023, vol. 52 . DOI: 10.1016/j.fbio.2023.102480.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Substance:
malonylgenistin (RF-00003922-PAR)
-
Analytical method code:
LC-MS (F026A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
6’’-O-Malonylgenistin by LC-ESI-QTOF-MS/MS
Composition #17: Zhou, Yufeng., Cao, Yuanxiao., Li, Jiaxun., Agar, Osman Tuncay., Barrow, Colin., Dunshea, Frank., Suleria, Hafiz A. R. Screening and characterization of phenolic compounds by LC‐ESI‐QTOF‐MS/MS and their antioxidant potentials in papaya fruit and their by‐products activities. food bioscience, 2023, vol. 52 . DOI: 10.1016/j.fbio.2023.102480.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Substance:
malonylglycitin (RF-00003923-PAR)
-
Analytical method code:
LC-MS (F026A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
6’’-O-Malonylglycitin by LC-ESI-QTOF-MS/MS
Composition #18: Zhou, Yufeng., Cao, Yuanxiao., Li, Jiaxun., Agar, Osman Tuncay., Barrow, Colin., Dunshea, Frank., Suleria, Hafiz A. R. Screening and characterization of phenolic compounds by LC‐ESI‐QTOF‐MS/MS and their antioxidant potentials in papaya fruit and their by‐products activities. food bioscience, 2023, vol. 52 . DOI: 10.1016/j.fbio.2023.102480.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Substance:
glycitin (RF-00003847-PAR)
-
Analytical method code:
LC-MS (F026A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Glycitin by LC-ESI-QTOF-MS/MS
Composition #19: Zhou, Yufeng., Cao, Yuanxiao., Li, Jiaxun., Agar, Osman Tuncay., Barrow, Colin., Dunshea, Frank., Suleria, Hafiz A. R. Screening and characterization of phenolic compounds by LC‐ESI‐QTOF‐MS/MS and their antioxidant potentials in papaya fruit and their by‐products activities. food bioscience, 2023, vol. 52 . DOI: 10.1016/j.fbio.2023.102480.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Substance:
malonyldaidzin (RF-00003921-PAR)
-
Analytical method code:
LC-MS (F026A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
6’’-O-Malonyldaidzin by LC-ESI-QTOF-MS/MS
Composition #20: Zhou, Yufeng., Cao, Yuanxiao., Li, Jiaxun., Agar, Osman Tuncay., Barrow, Colin., Dunshea, Frank., Suleria, Hafiz A. R. Screening and characterization of phenolic compounds by LC‐ESI‐QTOF‐MS/MS and their antioxidant potentials in papaya fruit and their by‐products activities. food bioscience, 2023, vol. 52 . DOI: 10.1016/j.fbio.2023.102480.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Substance:
epigallocatechin gallate (RF-00003802-PAR)
-
Analytical method code:
LC-MS (F026A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
(+)-Gallocatechin 3-O-gallate by LC-ESI-QTOF-MS/MS
Composition #21: Zhou, Yufeng., Cao, Yuanxiao., Li, Jiaxun., Agar, Osman Tuncay., Barrow, Colin., Dunshea, Frank., Suleria, Hafiz A. R. Screening and characterization of phenolic compounds by LC‐ESI‐QTOF‐MS/MS and their antioxidant potentials in papaya fruit and their by‐products activities. food bioscience, 2023, vol. 52 . DOI: 10.1016/j.fbio.2023.102480.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Substance:
gallocatechin (RF-00003822-PAR)
-
Analytical method code:
LC-MS (F026A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
(+)-Gallocatechin by LC-ESI-QTOF-MS/MS
Composition #22: Zhou, Yufeng., Cao, Yuanxiao., Li, Jiaxun., Agar, Osman Tuncay., Barrow, Colin., Dunshea, Frank., Suleria, Hafiz A. R. Screening and characterization of phenolic compounds by LC‐ESI‐QTOF‐MS/MS and their antioxidant potentials in papaya fruit and their by‐products activities. food bioscience, 2023, vol. 52 . DOI: 10.1016/j.fbio.2023.102480.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Substance:
gallic acid (RF-00003821-PAR)
-
Analytical method code:
LC-MS (F026A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Gallic acid by LC-ESI-QTOF-MS/MS
Composition #23: Zhou, Yufeng., Cao, Yuanxiao., Li, Jiaxun., Agar, Osman Tuncay., Barrow, Colin., Dunshea, Frank., Suleria, Hafiz A. R. Screening and characterization of phenolic compounds by LC‐ESI‐QTOF‐MS/MS and their antioxidant potentials in papaya fruit and their by‐products activities. food bioscience, 2023, vol. 52 . DOI: 10.1016/j.fbio.2023.102480.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Substance:
Esculetin (RF-00003667-PAR)
-
Analytical method code:
LC-MS (F026A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Esculetin by LC-ESI-QTOF-MS/MS
Composition #24: Zhou, Yufeng., Cao, Yuanxiao., Li, Jiaxun., Agar, Osman Tuncay., Barrow, Colin., Dunshea, Frank., Suleria, Hafiz A. R. Screening and characterization of phenolic compounds by LC‐ESI‐QTOF‐MS/MS and their antioxidant potentials in papaya fruit and their by‐products activities. food bioscience, 2023, vol. 52 . DOI: 10.1016/j.fbio.2023.102480.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Substance:
Isopimpinellin (RF-00003784-PAR)
-
Analytical method code:
LC-MS (F026A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Isopimpinellin by LC-ESI-QTOF-MS/MS
Composition #25: Zhou, Yufeng., Cao, Yuanxiao., Li, Jiaxun., Agar, Osman Tuncay., Barrow, Colin., Dunshea, Frank., Suleria, Hafiz A. R. Screening and characterization of phenolic compounds by LC‐ESI‐QTOF‐MS/MS and their antioxidant potentials in papaya fruit and their by‐products activities. food bioscience, 2023, vol. 52 . DOI: 10.1016/j.fbio.2023.102480.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Substance:
lignans (RF-00004361-PAR)
-
Analytical method code:
LC-MS (F026A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Lignans by LC-ESI-QTOF-MS/MS
Composition #26: Zhou, Yufeng., Cao, Yuanxiao., Li, Jiaxun., Agar, Osman Tuncay., Barrow, Colin., Dunshea, Frank., Suleria, Hafiz A. R. Screening and characterization of phenolic compounds by LC‐ESI‐QTOF‐MS/MS and their antioxidant potentials in papaya fruit and their by‐products activities. food bioscience, 2023, vol. 52 . DOI: 10.1016/j.fbio.2023.102480.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Substance:
Schisandrin (RF-00011059-PAR)
-
Analytical method code:
LC-MS (F026A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Schisandrin C by LC-ESI-QTOF-MS/MS
Composition #27: Zhou, Yufeng., Cao, Yuanxiao., Li, Jiaxun., Agar, Osman Tuncay., Barrow, Colin., Dunshea, Frank., Suleria, Hafiz A. R. Screening and characterization of phenolic compounds by LC‐ESI‐QTOF‐MS/MS and their antioxidant potentials in papaya fruit and their by‐products activities. food bioscience, 2023, vol. 52 . DOI: 10.1016/j.fbio.2023.102480.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Substance:
Isoflavonoids Isoflavonoids (RF-00000439-NTR)
-
Analytical method code:
LC-MS (F026A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Isoflavonoids by LC-ESI-QTOF-MS/MS
Composition #28: Zhou, Yufeng., Cao, Yuanxiao., Li, Jiaxun., Agar, Osman Tuncay., Barrow, Colin., Dunshea, Frank., Suleria, Hafiz A. R. Screening and characterization of phenolic compounds by LC‐ESI‐QTOF‐MS/MS and their antioxidant potentials in papaya fruit and their by‐products activities. food bioscience, 2023, vol. 52 . DOI: 10.1016/j.fbio.2023.102480.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Substance:
coumarins (RF-00004351-PAR)
-
Analytical method code:
LC-MS (F026A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Hydroxycoumarins by LC-ESI-QTOF-MS/MS
Composition #29: Zhou, Yufeng., Cao, Yuanxiao., Li, Jiaxun., Agar, Osman Tuncay., Barrow, Colin., Dunshea, Frank., Suleria, Hafiz A. R. Screening and characterization of phenolic compounds by LC‐ESI‐QTOF‐MS/MS and their antioxidant potentials in papaya fruit and their by‐products activities. food bioscience, 2023, vol. 52 . DOI: 10.1016/j.fbio.2023.102480.
[
DOI link]
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Substance:
Stilbenes (RF-00009766-PAR)
-
Analytical method code:
LC-MS (F026A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Stilbenes by LC-ESI-QTOF-MS/MS
Endpoint study
#1: SATRIJA, F., NANSEN, P., BJORN, H., MURTINI, S., HE, S. EFFECT OF PAPAYA LATEX AGAINST ASCARIS‐SUUM IN NATURALLY INFECTED‐PIGS. journal of helminthology, 1994, vol. 68, no. 4, p. 343–346. DOI: 10.1017/S0022149X00001619.
[
DOI link]
-
Study relevance:
Animal (target species) health
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Preparation/Extraction method:
Drying (dehydration) (A07KG)
-
Additional plant/substance description:
papaya latex
-
Type of toxicological test:
other (CHD008TT)
-
Guideline used:
No guideline followed
-
Tested organism:
Pig (as animal) (A057F)
-
-
Route of exposure:
ORAL: GAVAGE (OECD2231PL)
-
-
Unit of exposure duration:
Day (G134A)
-
Number of organisms dosed:
16
-
-
Endpoint measured:
Lowest observable effect concentration (CHD027EP)
-
Concentration unit:
Grams per kilogram body weight (G226A)
-
-
Critical effect:
Digestive (TOX18A)
-
Target tissue:
Digestive (TT002A)
-
Effect description:
diarrhoea
-
Effect or parameter linked to the endpoint:
food consumption (CHD007BE)
-
Internal remarks:
anthelmintic efficacy measured on Danish Landrace/Yorkshire cross-breed piglets
Endpoint study
#2: Shettima, Ibrahim., Rekwot, Peter Ibrahim., Ayo, Joseph Olusegun., Nwannenna, Agnes Ifeoma. Effects of Carica papaya peel meal‐based diets on rabbit bucks' spermiogram and reaction time. tropical animal health and production, 2024, vol. 56, no. 2 . DOI: 10.1007/s11250-024-03911-5.
[
DOI link]
-
Study relevance:
Animal (target species) health
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Preparation/Extraction method:
Drying (dehydration) (A07KG)
-
Type of toxicological test:
reproduction toxicity (CHD009TT)
-
Guideline used:
No guideline followed
-
Tested organism:
Rabbit (as animal) (A057T)
-
-
Route of exposure:
ORAL: FEED (OECD2230PL)
-
-
Unit of exposure duration:
Week (G205A)
-
Number of organisms dosed:
15
-
-
Endpoint measured:
Lowest observable effect concentration (CHD027EP)
-
Concentration unit:
Percent/volume (G088A)
-
-
Critical effect:
REPRODUCTIVE (TOX05A)
-
Target tissue:
urogenital: Testes (TT050A)
-
Effect description:
Significantly reduced the semen volume, sperm motility, and concentration. Increased the percent dead spermatozoa, total spermatozoa abnormalities, and sperm morphological defects
-
Effect or parameter linked to the endpoint:
reproduction (CHD014BE)
-
Internal remarks:
rabit Oryctolagus cuniculus
Endpoint study
#3: Kachi, Jolly Babangida., Fanwo, Roseline Ruth., Amali, Rosemary Patrick., Oludare, Tayo Timon. Assessment of Piscicidal Potentials of Carica papaya (Linnaeus, 1753) Leaves, Seeds, and Peel Powder on Juveniles of Clarias gariepinus (Burchell, 1822). uttar pradesh journal of zoology, 2024, vol. 45, no. 4, p. 193–204. DOI: 10.56557/UPJOZ/2024/v45i43922.
[
DOI link]
-
Study relevance:
Animal (target species) health
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Preparation/Extraction method:
Drying (dehydration) (A07KG)
-
Type of toxicological test:
acute toxicity (CHD016TT)
-
Guideline used:
No guideline followed
-
-
Route of exposure:
ORAL: DRINKING WATER (OECD2229PL)
-
-
Unit of exposure duration:
Hour (G099A)
-
Number of organisms dosed:
150
-
-
Endpoint measured:
Lethal dose rate in 50% of experimental organisms (CHD029EP)
-
Concentration unit:
Milligram/litre (G062A)
-
Effect concentration:
697.180
-
Critical effect:
SYSTEMIC (TOX01A)
-
Effect description:
Erratic swimming, Air gulping Loss of reflex, Abnormal vertical orientation, Jumping, Loss of buoyancy
-
Effect or parameter linked to the endpoint:
mortality (CHD010BE)
-
Internal remarks:
Test made on juvenille fish Clarias gariepinus similar to OECD guideline for Fish acute toxicity
Endpoint study
#4: Juhari, Nik Khairunnisa Khir., Abd Wahid, Nurul Bahiyah., Ramli, Suzita. A review: Antimicrobial activity and toxicity analysis of the peel of banana, pomegranate, papaya, and citrus fruits (lemon and orange). malaysian journal of microbiology, 2021, vol. 17, no. 4, p. 459–470. DOI: 10.21161/mjm.201076.
[
DOI link]
-
Study relevance:
Animal (target species) health
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Preparation/Extraction method:
Solvent extraction (A0BZR)
-
Additional plant/substance description:
queous extract of C.P peel
-
Type of toxicological test:
short-term toxicity (CHD017TT)
-
Guideline used:
No guideline followed
-
Tested organism:
Rat (as animal) (A0CNV)
-
Strain of test organism:
Wistar (CHD013ST)
-
-
Route of exposure:
ORAL: FEED (OECD2230PL)
-
-
Unit of exposure duration:
Day (G134A)
-
Number of organisms dosed:
35
-
-
Endpoint measured:
Lowest observable effect concentration (CHD027EP)
-
Concentration unit:
Milligram/kilogram (G061A)
-
Effect concentration:
100
-
Critical effect:
REPRODUCTIVE (TOX05A)
-
Target tissue:
urogenital: Testes (TT050A)
-
Effect description:
death, disorganization of testicular architecture and inflammatory cells around the seminiferous tubule
-
Effect or parameter linked to the endpoint:
reproduction (CHD014BE)
-
Internal remarks:
100 mg/kg of peels effect to fertility, LD50=1000 mg