EFSA Compendium of Botanicals

Draft - work in progress

Adenia hondala (Gaertn.) W.J.de Wilde // Adenia palmata Engl.

Family:: Passifloraceae
Approval state:: Approved
Number of articles retrieved:: 1
Number of processed references:: 2

Compositions

Endpoint Studies

#1: Poisoning of children - digestive problems, death #2: Poisoning with leaves - vomiting, bloody diarrhoea, fever

Genotoxicity

Endpoint study #1: Lucas, G. N. Plant poisoning: A hospital-based study in Sri Lanka. indian journal of pediatrics, 1997, vol. 64, no. 4, p. 495–502. DOI: 10.1007/BF02737755. [DOI link]

Study relevance:

Human health
Plant part:

Fruit unspecified (as part-nature) (A067D)
Additional plant/substance description:

unspecified
Type of toxicological test:

case report (CHD060TT)
Tested organism:

Human (as organism) (A056J)
Sex:

No data
Route of exposure:

ORAL: UNSPECIFIED (OECD2234PL)
Exposure duration:

6.0
Unit of exposure duration:

Hour (G099A)
Number of organisms dosed:

8
Endpoint measured:

Dose not reported (CHD066EP)
Critical effect:

Digestive (TOX18A)
Target tissue:

Digestive (TT002A)
Effect description:

Vomiting and dizziness, bloody diarrhoea; death of 5 year old boy - postmortem examination showed necrotising enteritis.
Effect or parameter linked to the endpoint:

mortality (CHD010BE)
Internal remarks:

Poisoning of children - digestive problems, death

Endpoint study #2: Ratnatilaka, Asoka., Yakandawala, Deepthi., Ratnayake, Janaka., Sugathadasa, Samantha. Poisoning with "hondala" leaves due to misidentification as "passion fruit" leaves. . ceylon medical journal, 2003, vol. 48, no. 1, p. 23–23. .

Study relevance:

Human health
Plant part:

Leaves (as part-nature) (A0EKT)
Preparation/Extraction method:

Fresh (A166Y)
Type of toxicological test:

case report (CHD060TT)
Number of organisms dosed:

4
Endpoint measured:

Dose not reported (CHD066EP)
Critical effect:

Digestive (TOX18A)
Target tissue:

Digestive (TT002A)
Effect description:

Vomiting, bloody diarrhoea, fever
Effect or parameter linked to the endpoint:

other (CHD003BE)
Internal remarks:

Poisoning with leaves - vomiting, bloody diarrhoea, fever