EFSA Compendium of Botanicals

Draft - work in progress

Wikstroemia indica (L.) C.A.Mey.

Family:: Thymelaeaceae
Approval state:: Approved
Number of articles retrieved:: 2
Number of processed references:: 2

Compositions

#1: daphnoretin and daphnoretin-7-O-β-D-glucosid #2: gallic acid #3: emodin monomethyl ether #4: Chrysophanol #5: umbelliferone #6: Coumarins in roots #7: Lignans in roots

Endpoint Studies

Genotoxicity

Composition #1: Yi, Wen-yan., Liu, Ming., Chen, Min., Li, Wei., Lin, Chang., Liu, Si-yao., Zhou, Ying. Chemical constituents of Wikstroemia indica. shizhen guoyi guoyao, 2012, vol. 23, no. 12, p. 3001–3003. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol acetate
Substance:

daphnoretin (RF-00004252-PAR)
Additional substance description:

daphnoretin and daphnoretin-7-O-β-D-glucosid
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

daphnoretin and daphnoretin-7-O-β-D-glucosid

Composition #2: Yi, Wen-yan., Liu, Ming., Chen, Min., Li, Wei., Lin, Chang., Liu, Si-yao., Zhou, Ying. Chemical constituents of Wikstroemia indica. shizhen guoyi guoyao, 2012, vol. 23, no. 12, p. 3001–3003. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol acetate
Substance:

gallic acid (RF-00003821-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

gallic acid

Composition #3: Yi, Wen-yan., Liu, Ming., Chen, Min., Li, Wei., Lin, Chang., Liu, Si-yao., Zhou, Ying. Chemical constituents of Wikstroemia indica. shizhen guoyi guoyao, 2012, vol. 23, no. 12, p. 3001–3003. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol acetate
Substance:

Emodin (RF-00003798-PAR)
Additional substance description:

emodin monomethyl ether
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

emodin monomethyl ether

Composition #4: Yi, Wen-yan., Liu, Ming., Chen, Min., Li, Wei., Lin, Chang., Liu, Si-yao., Zhou, Ying. Chemical constituents of Wikstroemia indica. shizhen guoyi guoyao, 2012, vol. 23, no. 12, p. 3001–3003. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol acetate
Substance:

chrysophanol (RF-00003737-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Chrysophanol

Composition #5: Yi, Wen-yan., Liu, Ming., Chen, Min., Li, Wei., Lin, Chang., Liu, Si-yao., Zhou, Ying. Chemical constituents of Wikstroemia indica. shizhen guoyi guoyao, 2012, vol. 23, no. 12, p. 3001–3003. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol acetate
Substance:

umbelliferone (RF-00004096-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

umbelliferone

Composition #6: Kato, Mamoru., He, Yu-Min., Dibwe, Dya Fta., Li, Feng., Awale, Suresh., Kadota, Shigetoshi., Tezuka, Yasuhiro. New Guaian-type Sesquiterpene from Wikstroemia indica. natural product communications, 2014, vol. 9, no. 1, p. 1–2. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

coumarins (RF-00004351-PAR)
Additional substance description:

7-methoxycoumarin, 7-hydroxycoumarin (umbelliferone), daphnogitin, daphnoretin
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Analytical method - additional description:

TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Coumarins in roots

Composition #7: Kato, Mamoru., He, Yu-Min., Dibwe, Dya Fta., Li, Feng., Awale, Suresh., Kadota, Shigetoshi., Tezuka, Yasuhiro. New Guaian-type Sesquiterpene from Wikstroemia indica. natural product communications, 2014, vol. 9, no. 1, p. 1–2. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

arctigenin; matairesinol; trachelogenin; nortrachelogenin; hinokinin; kusunokinin; pinoresinol; salicifoliol
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Analytical method - additional description:

TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Lignans in roots