EFSA Compendium of Botanicals

Draft - work in progress

Dracaena liberica (Gérôme & Labroy) Byng & Christenh. // Sansevieria liberica Gérôme & Labroy

Family:: Asparagaceae
Approval state:: Approved
Number of articles retrieved:: 3
Number of processed references:: 3

Compositions

#1: Saponins in leaves #2: Alkaloids in leaves #3: Alkaloids in roots #4: Saponins in roots #5: Anthraquinones in roots #6: Tannins in roots

Endpoint Studies

#1: Mean of kidney weight increased

Genotoxicity

Composition #1: Ikewuchi, C. C., Ikewuchi, C. J., Ayalogu, O. E., Onyeike, N. E. Proximate and phytochemical profile of Sansevieria liberica Gerome and Labroy. journal of applied sciences and environmental management, 2010, vol. 14, no. 2, p. 103–106. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Additional extraction description:

unspecified
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Phytochemical screening (F604A)
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.15
Internal remarks:

Saponins in leaves

Composition #2: Ikewuchi, C. C., Ikewuchi, C. J., Ayalogu, O. E., Onyeike, N. E. Proximate and phytochemical profile of Sansevieria liberica Gerome and Labroy. journal of applied sciences and environmental management, 2010, vol. 14, no. 2, p. 103–106. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Additional extraction description:

unspecified
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids in leaves

Composition #3: Adeyemi, O. O., Akindele, A. J., Ogunleye, E. A. Evaluation of the antidiarrhoeal effect of Sanseviera liberica Gerome & Labroy (Agavaceae) root extract . journal of ethnopharmacology, 2009, vol. 123, no. 3, p. 459–463. DOI: 10.1016/j.jep.2009.03.023. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids in roots

Composition #4: Adeyemi, O. O., Akindele, A. J., Ogunleye, E. A. Evaluation of the antidiarrhoeal effect of Sanseviera liberica Gerome & Labroy (Agavaceae) root extract . journal of ethnopharmacology, 2009, vol. 123, no. 3, p. 459–463. DOI: 10.1016/j.jep.2009.03.023. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Saponins in roots

Composition #5: Adeyemi, O. O., Akindele, A. J., Ogunleye, E. A. Evaluation of the antidiarrhoeal effect of Sanseviera liberica Gerome & Labroy (Agavaceae) root extract . journal of ethnopharmacology, 2009, vol. 123, no. 3, p. 459–463. DOI: 10.1016/j.jep.2009.03.023. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water
Substance:

anthraquinones (RF-00004343-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Anthraquinones in roots

Composition #6: Adeyemi, O. O., Akindele, A. J., Ogunleye, E. A. Evaluation of the antidiarrhoeal effect of Sanseviera liberica Gerome & Labroy (Agavaceae) root extract . journal of ethnopharmacology, 2009, vol. 123, no. 3, p. 459–463. DOI: 10.1016/j.jep.2009.03.023. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins in roots

Endpoint study #1: Amida, Muibat B., Yemitan, Omoniyi K., Adeyemi, Olufunmilayo O. Toxicological assessment of the aqueous root extract of Sanseviera liberica Gerome and Labroy (Agavaceae) . journal of ethnopharmacology, 2007, vol. 113, no. 1, p. 171–175. DOI: 10.1016/j.jep.2007.03.033. [DOI link]

Study relevance:

Human health
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Preparation/Extraction method:

Solvent extraction (A0BZR)
Additional plant/substance description:

water
Type of toxicological test:

chronic/long term toxicity (CHD004TT)
Tested organism:

House mouse (as animal) (A0CNT)
Sex:

Male/Female
Route of exposure:

ORAL: UNSPECIFIED (OECD2234PL)
Exposure duration:

52.0
Unit of exposure duration:

Day (G134A)
Number of organisms dosed:

32
Control groups used:

yes
Endpoint measured:

Concentration at or below which no ecologically adverse effects would be expected (CHD078EP)
Concentration unit:

Grams per kilogram body weight (G226A)
Effect concentration:

2
Critical effect:

NEPHROTOXICITY (TOX03A)
Target tissue:

urogenital: Kidneys (TT046A)
Effect description:

Mean of kidney weight increased
Effect or parameter linked to the endpoint:

organ weights (CHD012BE)
Internal remarks:

Mean of kidney weight increased