EFSA Compendium of Botanicals

Draft - work in progress

Cryptostegia madagascariensis Bojer ex Decne.

Family:: Apocynaceae
Approval state:: Approved
Number of articles retrieved:: 1
Number of processed references:: 1

Compositions

#1: 16-anhydrogitoxigenin in aerial parts #2: cardiac glycosides (16-anhydrogitoxigenin-3-rhamnoside,16-propionylgitoxigenin-3-rhamnoside, 14,16- dianhydrogitoxigenin-3-rhamnoside) in aerial parts #3: Oleandrigenin in aerial parts #4: Digitoxigenin in aerial parts

Endpoint Studies

Genotoxicity

Composition #1: SANDUJA, R., LO, WYR., EULER, KL., ALAM, M., MORTON, JF. CARDENOLIDES OF CRYPTOSTEGIA-MADAGASCARIENSIS. journal of natural products, 1984, vol. 47, no. 2, p. 260–265. DOI: 10.1021/np50032a004. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

16-anhydrogitoxigenin (RF-00004115-PAR)
Additional substance description:

16-anhydrogitoxigenin and derivatives
Analytical method code:

Chromatographic tests (F015A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

16-anhydrogitoxigenin in aerial parts

Composition #2: SANDUJA, R., LO, WYR., EULER, KL., ALAM, M., MORTON, JF. CARDENOLIDES OF CRYPTOSTEGIA-MADAGASCARIENSIS. journal of natural products, 1984, vol. 47, no. 2, p. 260–265. DOI: 10.1021/np50032a004. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

cardiac glycosides (RF-00010823-PAR)
Additional substance description:

16-anhydrogitoxigenin-3-rhamnoside,16-propionylgitoxigenin-3-rhamnoside, 14,16- dianhydrogitoxigenin-3-rhamnoside
Analytical method code:

Chromatographic tests (F015A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

cardiac glycosides (16-anhydrogitoxigenin-3-rhamnoside,16-propionylgitoxigenin-3-rhamnoside, 14,16- dianhydrogitoxigenin-3-rhamnoside) in aerial parts

Composition #3: SANDUJA, R., LO, WYR., EULER, KL., ALAM, M., MORTON, JF. CARDENOLIDES OF CRYPTOSTEGIA-MADAGASCARIENSIS. journal of natural products, 1984, vol. 47, no. 2, p. 260–265. DOI: 10.1021/np50032a004. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

oleandrigenin (RF-00003523-PAR)
Analytical method code:

Chromatographic tests (F015A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Oleandrigenin in aerial parts

Composition #4: SANDUJA, R., LO, WYR., EULER, KL., ALAM, M., MORTON, JF. CARDENOLIDES OF CRYPTOSTEGIA-MADAGASCARIENSIS. journal of natural products, 1984, vol. 47, no. 2, p. 260–265. DOI: 10.1021/np50032a004. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

digitoxigenin (RF-00004273-PAR)
Analytical method code:

Chromatographic tests (F015A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Digitoxigenin in aerial parts