EFSA Compendium of Botanicals

Draft - work in progress

Cotoneaster pannosus Franch.

Family:: Rosaceae
Approval state:: Approved
Number of articles retrieved:: 1
Number of processed references:: 1

Compositions

Endpoint Studies

Genotoxicity

Composition #1: Les, Francisco., Lopez, Victor., Caprioli, Giovanni., Iannarelli, Romilde., Fiorini, Dennis., Innocenti, Marzia., Bellumori, Maria., Maggi, Filippo. Chemical constituents, radical scavenging activity and enzyme inhibitory capacity of fruits from Cotoneaster pannosus Franch . food & function, 2017, vol. 8, no. 5, p. 1775–1784. DOI: 10.1039/c7fo00330g. [DOI link]

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol:water 70:30 (v/v)
Substance:

gallic acid (RF-00003821-PAR)
Analytical method code:

HPLC with standard detection methods (F019A)
Analytical method - additional description:

MS
Result unit:

Milligram/kilogram (G061A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

308.4
Internal remarks:

Gallic acid in fruits

Endpoint study #1: Les, Francisco., Lopez, Victor., Caprioli, Giovanni., Iannarelli, Romilde., Fiorini, Dennis., Innocenti, Marzia., Bellumori, Maria., Maggi, Filippo. Chemical constituents, radical scavenging activity and enzyme inhibitory capacity of fruits from Cotoneaster pannosus Franch . food & function, 2017, vol. 8, no. 5, p. 1775–1784. DOI: 10.1039/c7fo00330g. [DOI link]

Study relevance:

Human health
Plant part:

Fruit unspecified (as part-nature) (A067D)
Preparation/Extraction method:

Solvent extraction (A0BZR)
Additional plant/substance description:

unspecified
Type of toxicological test:

in vitro (CHD061TT)
Endpoint measured:

Half maximal inhibitory concentration (CHD021EP)
Concentration unit:

Microgram/millilitre (G052A)
Effect concentration:

12.74-27.82
Critical effect:

Digestive (TOX18A)
Target tissue:

digestive: Pancreas (TT024A)
Effect description:

alpha-glucosidase inhibition
Effect or parameter linked to the endpoint:

enzyme inhibition (CHD032BE)
Internal remarks:

alpha-glucosidase inhibition