Composition #1: Etebari, M., Ghannadi, A., Jafarian-Dehkordi, A., Ahmadi, F. Genotoxicity evaluation of aqueous extracts of Cotoneaster discolor and Alhagi pseudalhagi by comet assay. journal of research in medical sciences, 2012, vol. 17, no. SUPPL.2, p. S237–S241. .
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Plant part:
Unspecified (A07XD)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Water/NaHCO3
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Substance:
Mannitol (RF-00000186-ADD)
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Analytical method code:
Micromethod dilution (in microtiter plate) (F131A)
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Analytical method - additional description:
titration with 0.05 iodine
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
42.55
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Internal remarks:
Mannitol (spec. tox.)
Genotox #1: Etebari, M., Ghannadi, A., Jafarian-Dehkordi, A., Ahmadi, F. Genotoxicity evaluation of aqueous extracts of Cotoneaster discolor and Alhagi pseudalhagi by comet assay. journal of research in medical sciences, 2012, vol. 17, no. SUPPL.2, p. S237–S241. .
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Study category:
Genotoxicity
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Type of toxicological test:
single cell gel/comet assay in mammalian cells for detection of DNA damage (CHD040TT)
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Tested organism:
Human (as organism) (A056J)
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Strain of test organism:
Hep G2 human cell line (CHD114ST)
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Endpoint measured:
DNA damage and/or repair
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Remarks on genotox study:
Genotoxicity (mannitol extracted from C. discolor was genotoxic at concentrations of 100 mg/ml; 50 mg0ml).
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Internal remarks:
Genotoxicity
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Internal ID:
eid=2-s2.0-84880620386
