EFSA Compendium of Botanicals

Draft - work in progress

Papaver cambricum L. // Meconopsis cambrica (L.) Vig.

Family:: Papaveraceae
Approval state:: Approved
Number of articles retrieved:: 100
Number of processed references:: 5

Compositions

#1: Sanguinarine (herb) #2: protopine (herb) #3: Sanguinarine (root) #4: protopine (root) #5: N-methyl-mecambridine (unspecified) #6: papaverrubine C,D (unspecified) #7: palmatine (unspecified) #8: Meconic acid (unspecified) #9: S-mecambrine (unspecified) #10: berberine (unspecified) #11: S-amurine (unspecified) #12: S(-)-Flavinantine (unspecified) #13: roemerine (unspecified) #14: magnoflorine (unspecified) #15: coptisine (unspecified) #16: Nudicaulins (petals) #17: N,N-dimethyl-hernovine (unspecified plant part) #18: Protopine (unspecified plant part)) #19: (- )-N-methylcrotonosine (roots) #20: (+)-magnoflorine (roots) #21: mecambrine (roots) #22: flavinantine (roots) #23: amurine (roots) #24: pronuciferine (roots) #25: mecambridine (roots) #26: glaziovine (roots) #27: Total alkaloids (roots) #28: sanguinarine (roots) #29: Total alkaloids (flower) #30: Total alkaloids (stem) #31: Total alkaloids (fruit)

Endpoint Studies

Genotoxicity

Composition #1: Petruczynik Anna., Misiurek Justyna., Waksmundzka-Hajnos Monika., Plech Tomasz., Tuzimski Tomasz., Kapron Barbara., Misiurek Dorota., Szultka-Mlynska Malgorzata., Buszewski Boguslaw. Determination of Selected Isoquinoline Alkaloids from Mahonia Aquifolia; Meconopsis Cambrica; Corydalis Lutea; Dicentra Spectabilis; Fumaria Officinalis; Macleaya Cordata Extracts by HPLC-DAD and Comparison of Their Cytotoxic Activity. toxins, 2019, p. 11(10). .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

chloroform
Substance:

sanguinarine (RF-00004040-PAR)
Analytical method code:

HPLC-DAD (F587A)
Analytical method - additional description:

HPLC-MS
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.0542
Internal remarks:

Sanguinarine (herb)

Composition #2: Petruczynik Anna., Misiurek Justyna., Waksmundzka-Hajnos Monika., Plech Tomasz., Tuzimski Tomasz., Kapron Barbara., Misiurek Dorota., Szultka-Mlynska Malgorzata., Buszewski Boguslaw. Determination of Selected Isoquinoline Alkaloids from Mahonia Aquifolia; Meconopsis Cambrica; Corydalis Lutea; Dicentra Spectabilis; Fumaria Officinalis; Macleaya Cordata Extracts by HPLC-DAD and Comparison of Their Cytotoxic Activity. toxins, 2019, p. 11(10). .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

chloroform
Substance:

protopine (RF-00004010-PAR)
Analytical method code:

HPLC-DAD (F587A)
Analytical method - additional description:

HPLC-MS
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.0787
Internal remarks:

protopine (herb)

Composition #3: Petruczynik Anna., Misiurek Justyna., Waksmundzka-Hajnos Monika., Plech Tomasz., Tuzimski Tomasz., Kapron Barbara., Misiurek Dorota., Szultka-Mlynska Malgorzata., Buszewski Boguslaw. Determination of Selected Isoquinoline Alkaloids from Mahonia Aquifolia; Meconopsis Cambrica; Corydalis Lutea; Dicentra Spectabilis; Fumaria Officinalis; Macleaya Cordata Extracts by HPLC-DAD and Comparison of Their Cytotoxic Activity. toxins, 2019, p. 11(10). .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

chloroform
Substance:

sanguinarine (RF-00004040-PAR)
Analytical method code:

HPLC-DAD (F587A)
Analytical method - additional description:

HPLC-MS
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.0504
Internal remarks:

Sanguinarine (root)

Composition #4: Petruczynik Anna., Misiurek Justyna., Waksmundzka-Hajnos Monika., Plech Tomasz., Tuzimski Tomasz., Kapron Barbara., Misiurek Dorota., Szultka-Mlynska Malgorzata., Buszewski Boguslaw. Determination of Selected Isoquinoline Alkaloids from Mahonia Aquifolia; Meconopsis Cambrica; Corydalis Lutea; Dicentra Spectabilis; Fumaria Officinalis; Macleaya Cordata Extracts by HPLC-DAD and Comparison of Their Cytotoxic Activity. toxins, 2019, p. 11(10). .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

chloroform
Substance:

protopine (RF-00004010-PAR)
Analytical method code:

HPLC-DAD (F587A)
Analytical method - additional description:

HPLC-MS
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.0236
Internal remarks:

protopine (root)

Composition #5: Tetenyi, P., Rauter, AP., Palma, FB., Justino, J., Araujo, ME., PinaDosSantos, S. Chemodifferentiation of papavereae from coasts of the Black-Sea to the Atlantic. natural products in the new millennium: prospects and industrial application, 2002, vol. 47, p. 173–181. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Additional extraction description:

unspecified
Substance:

protoberberine (RF-00003553-PAR)
Additional substance description:

N-methyl-mecambridine
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

N-methyl-mecambridine (unspecified)

Composition #6: Tetenyi, P., Rauter, AP., Palma, FB., Justino, J., Araujo, ME., PinaDosSantos, S. Chemodifferentiation of papavereae from coasts of the Black-Sea to the Atlantic. natural products in the new millennium: prospects and industrial application, 2002, vol. 47, p. 173–181. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Additional extraction description:

unspecified
Substance:

Rhoeadine (RF-00011047-PAR)
Additional substance description:

papaverrubine
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

papaverrubine C,D (unspecified)

Composition #7: Tetenyi, P., Rauter, AP., Palma, FB., Justino, J., Araujo, ME., PinaDosSantos, S. Chemodifferentiation of papavereae from coasts of the Black-Sea to the Atlantic. natural products in the new millennium: prospects and industrial application, 2002, vol. 47, p. 173–181. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Additional extraction description:

unspecified
Substance:

palmatine (RF-00003971-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

palmatine (unspecified)

Composition #8: Tetenyi, P., Rauter, AP., Palma, FB., Justino, J., Araujo, ME., PinaDosSantos, S. Chemodifferentiation of papavereae from coasts of the Black-Sea to the Atlantic. natural products in the new millennium: prospects and industrial application, 2002, vol. 47, p. 173–181. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Additional extraction description:

unspecified
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

Meconic acid
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Meconic acid (unspecified)

Composition #9: Tetenyi, P., Rauter, AP., Palma, FB., Justino, J., Araujo, ME., PinaDosSantos, S. Chemodifferentiation of papavereae from coasts of the Black-Sea to the Atlantic. natural products in the new millennium: prospects and industrial application, 2002, vol. 47, p. 173–181. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Additional extraction description:

unspecified
Substance:

mecambrine (RF-00003484-PAR)
Additional substance description:

S-mecambrine
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

S-mecambrine (unspecified)

Composition #10: Tetenyi, P., Rauter, AP., Palma, FB., Justino, J., Araujo, ME., PinaDosSantos, S. Chemodifferentiation of papavereae from coasts of the Black-Sea to the Atlantic. natural products in the new millennium: prospects and industrial application, 2002, vol. 47, p. 173–181. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Additional extraction description:

unspecified
Substance:

berberine (RF-00003706-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

berberine (unspecified)

Composition #11: Tetenyi, P., Rauter, AP., Palma, FB., Justino, J., Araujo, ME., PinaDosSantos, S. Chemodifferentiation of papavereae from coasts of the Black-Sea to the Atlantic. natural products in the new millennium: prospects and industrial application, 2002, vol. 47, p. 173–181. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Additional extraction description:

unspecified
Substance:

Isoquinoline alkaloids (RF-00004391-PAR)
Additional substance description:

S-amurine
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

S-amurine (unspecified)

Composition #12: Tetenyi, P., Rauter, AP., Palma, FB., Justino, J., Araujo, ME., PinaDosSantos, S. Chemodifferentiation of papavereae from coasts of the Black-Sea to the Atlantic. natural products in the new millennium: prospects and industrial application, 2002, vol. 47, p. 173–181. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Additional extraction description:

unspecified
Substance:

Flavinantine (RF-00010935-PAR)
Additional substance description:

S(-)-Flavinantine
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

S(-)-Flavinantine (unspecified)

Composition #13: Tetenyi, P., Rauter, AP., Palma, FB., Justino, J., Araujo, ME., PinaDosSantos, S. Chemodifferentiation of papavereae from coasts of the Black-Sea to the Atlantic. natural products in the new millennium: prospects and industrial application, 2002, vol. 47, p. 173–181. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Additional extraction description:

unspecified
Substance:

Roemerine (RF-00011241-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

roemerine (unspecified)

Composition #14: Tetenyi, P., Rauter, AP., Palma, FB., Justino, J., Araujo, ME., PinaDosSantos, S. Chemodifferentiation of papavereae from coasts of the Black-Sea to the Atlantic. natural products in the new millennium: prospects and industrial application, 2002, vol. 47, p. 173–181. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Additional extraction description:

unspecified
Substance:

magnoflorine (RF-00003919-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

magnoflorine (unspecified)

Composition #15: Tetenyi, P., Rauter, AP., Palma, FB., Justino, J., Araujo, ME., PinaDosSantos, S. Chemodifferentiation of papavereae from coasts of the Black-Sea to the Atlantic. natural products in the new millennium: prospects and industrial application, 2002, vol. 47, p. 173–181. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Additional extraction description:

unspecified
Substance:

coptisine (RF-00004215-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

coptisine (unspecified)

Composition #16: Tatsis, Evangelos C., Boehm, Hartmut., Schneider, Bernd. Occurrence of nudicaulin structural variants in flowers of papaveraceous species. phytochemistry, 2013, vol. 92, p. 105–112. DOI: 10.1016/j.phytochem.2013.04.011. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Nudicauline (RF-00011104-PAR)
Additional substance description:

Nudicauline I and II
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.17-1.44
Internal remarks:

Nudicaulins (petals)

Composition #17: Och, Anna., Szewczyk, Katarzyna., Pecio, Lukasz., Stochmal, Anna., Zaluski, Daniel., Bogucka-Kocka, Anna. UPLC-MS/MS Profile of Alkaloids with Cytotoxic Properties of Selected Medicinal Plants of the Berberidaceae and Papaveraceae Families. oxidative medicine and cellular longevity, 2017, vol. 2017 . DOI: 10.1155/2017/9369872. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

hernovine (RF-00011235-PAR)
Additional substance description:

N,N-dimethyl-hernovine
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Analytical method - additional description:

UPLC-MS/MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

N,N-dimethyl-hernovine (unspecified plant part)

Composition #18: Och, Anna., Szewczyk, Katarzyna., Pecio, Lukasz., Stochmal, Anna., Zaluski, Daniel., Bogucka-Kocka, Anna. UPLC-MS/MS Profile of Alkaloids with Cytotoxic Properties of Selected Medicinal Plants of the Berberidaceae and Papaveraceae Families. oxidative medicine and cellular longevity, 2017, vol. 2017 . DOI: 10.1155/2017/9369872. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

protopine (RF-00004010-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Analytical method - additional description:

UPLC-MS/MS
Result unit:

Microgram/gram (G049A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

74.4
Internal remarks:

Protopine (unspecified plant part))

Composition #19: HEMINGWAY, SR., PHILLIPSON, JD., VERPOORTE, R. MECONOPSIS-CAMBRICA ALKALOIDS. journal of natural products, 1981, vol. 44, no. 1, p. 67–74. DOI: 10.1021/np50013a012. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetic acid (5%) and methanol
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

(- )-N-methylcrotonosine
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Analytical method - additional description:

TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

(- )-N-methylcrotonosine (roots)

Composition #20: HEMINGWAY, SR., PHILLIPSON, JD., VERPOORTE, R. MECONOPSIS-CAMBRICA ALKALOIDS. journal of natural products, 1981, vol. 44, no. 1, p. 67–74. DOI: 10.1021/np50013a012. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetic acid (5%) and methanol
Substance:

magnoflorine (RF-00003919-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Analytical method - additional description:

TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

(+)-magnoflorine (roots)

Composition #21: HEMINGWAY, SR., PHILLIPSON, JD., VERPOORTE, R. MECONOPSIS-CAMBRICA ALKALOIDS. journal of natural products, 1981, vol. 44, no. 1, p. 67–74. DOI: 10.1021/np50013a012. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetic acid (5%) and methanol
Substance:

mecambrine (RF-00003484-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Analytical method - additional description:

TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

mecambrine (roots)

Composition #22: HEMINGWAY, SR., PHILLIPSON, JD., VERPOORTE, R. MECONOPSIS-CAMBRICA ALKALOIDS. journal of natural products, 1981, vol. 44, no. 1, p. 67–74. DOI: 10.1021/np50013a012. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetic acid (5%) and methanol
Substance:

Flavinantine (RF-00010935-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Analytical method - additional description:

TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

flavinantine (roots)

Composition #23: HEMINGWAY, SR., PHILLIPSON, JD., VERPOORTE, R. MECONOPSIS-CAMBRICA ALKALOIDS. journal of natural products, 1981, vol. 44, no. 1, p. 67–74. DOI: 10.1021/np50013a012. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetic acid (5%) and methanol
Substance:

Isoquinoline alkaloids (RF-00004391-PAR)
Additional substance description:

Amurine
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Analytical method - additional description:

TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

amurine (roots)

Composition #24: HEMINGWAY, SR., PHILLIPSON, JD., VERPOORTE, R. MECONOPSIS-CAMBRICA ALKALOIDS. journal of natural products, 1981, vol. 44, no. 1, p. 67–74. DOI: 10.1021/np50013a012. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetic acid (5%) and methanol
Substance:

pronuciferine (RF-00011238-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Analytical method - additional description:

TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

pronuciferine (roots)

Composition #25: HEMINGWAY, SR., PHILLIPSON, JD., VERPOORTE, R. MECONOPSIS-CAMBRICA ALKALOIDS. journal of natural products, 1981, vol. 44, no. 1, p. 67–74. DOI: 10.1021/np50013a012. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetic acid (5%) and methanol
Substance:

protoberberine (RF-00003553-PAR)
Additional substance description:

mecambridine
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Analytical method - additional description:

TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

mecambridine (roots)

Composition #26: HEMINGWAY, SR., PHILLIPSON, JD., VERPOORTE, R. MECONOPSIS-CAMBRICA ALKALOIDS. journal of natural products, 1981, vol. 44, no. 1, p. 67–74. DOI: 10.1021/np50013a012. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetic acid (5%) and methanol
Substance:

Glaziovine (RF-00011142-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Analytical method - additional description:

TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

glaziovine (roots)

Composition #27: HEMINGWAY, SR., PHILLIPSON, JD., VERPOORTE, R. MECONOPSIS-CAMBRICA ALKALOIDS. journal of natural products, 1981, vol. 44, no. 1, p. 67–74. DOI: 10.1021/np50013a012. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetic acid (5%) and chloroform
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Analytical method - additional description:

TLC
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.2
Internal remarks:

Total alkaloids (roots)

Composition #28: HEMINGWAY, SR., PHILLIPSON, JD., VERPOORTE, R. MECONOPSIS-CAMBRICA ALKALOIDS. journal of natural products, 1981, vol. 44, no. 1, p. 67–74. DOI: 10.1021/np50013a012. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetic acid (5%) and methanol
Substance:

sanguinarine (RF-00004040-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Analytical method - additional description:

TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

sanguinarine (roots)

Composition #29: HEMINGWAY, SR., PHILLIPSON, JD., VERPOORTE, R. MECONOPSIS-CAMBRICA ALKALOIDS. journal of natural products, 1981, vol. 44, no. 1, p. 67–74. DOI: 10.1021/np50013a012. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetic acid (5%) and chloroform
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Analytical method - additional description:

TLC
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.4
Internal remarks:

Total alkaloids (flower)

Composition #30: HEMINGWAY, SR., PHILLIPSON, JD., VERPOORTE, R. MECONOPSIS-CAMBRICA ALKALOIDS. journal of natural products, 1981, vol. 44, no. 1, p. 67–74. DOI: 10.1021/np50013a012. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetic acid (5%) and chloroform
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Analytical method - additional description:

TLC
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.08
Internal remarks:

Total alkaloids (stem)

Composition #31: HEMINGWAY, SR., PHILLIPSON, JD., VERPOORTE, R. MECONOPSIS-CAMBRICA ALKALOIDS. journal of natural products, 1981, vol. 44, no. 1, p. 67–74. DOI: 10.1021/np50013a012. [DOI link]

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetic acid (5%) and chloroform
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Analytical method - additional description:

TLC
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.19
Internal remarks:

Total alkaloids (fruit)