EFSA Compendium of Botanicals

Draft - work in progress

Papaver puniceum (Maxim.) Christenh. & Byng // Meconopsis punicea Maxim

Family:: Papaveraceae
Approval state:: Approved
Number of articles retrieved:: 33
Number of processed references:: 4

Compositions

#1: cinnamic acid #2: Quinolizidine alkaloids #3: coumaric acid #4: dihydrosanguinarine in aerial parts #5: berberine in aerial parts #6: Karachine in aerial parts #7: hydnocarpin in aerial parts #8: protopine in aerial parts #9: Hexyl cinnamaldehyde in whole plant #10: Naphthalene derivatives in whole plant #11: Berberine in flowers

Endpoint Studies

Genotoxicity

Composition #1: Liu, Songyu., Wang, Xiankai. Investigation of the chemical constituents of Tibetan drug Meconopsis punicea. zhongyao tongbao, 1986, vol. 11, no. 6, p. 360–2. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Substance:

Cinnamic acid (RF-00008530-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

cinnamic acid

Composition #2: Liu, Songyu., Wang, Xiankai. Investigation of the chemical constituents of Tibetan drug Meconopsis punicea. zhongyao tongbao, 1986, vol. 11, no. 6, p. 360–2. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Substance:

Quinolizidine alkaloids (RF-00004327-PAR)
Additional substance description:

alborine, Mecambridine and methoxymecambridine
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Quinolizidine alkaloids

Composition #3: Liu, Songyu., Wang, Xiankai. Investigation of the chemical constituents of Tibetan drug Meconopsis punicea. zhongyao tongbao, 1986, vol. 11, no. 6, p. 360–2. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Substance:

p-coumaric acid (RF-00010717-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

coumaric acid

Composition #4: Wu, Haifeng., Song, Zhijun., Zhu, Huajie., Peng, Shulin., Zhang, Xiaofeng. Chemical constituents of Meconopsis punicea. tianran chanwu yanjiu yu kaifa, 2011, vol. 23, no. 2, p. 202–207. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Substance:

dihydrosanguinarine (RF-00003780-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

GC-MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

dihydrosanguinarine in aerial parts

Composition #5: Wu, Haifeng., Song, Zhijun., Zhu, Huajie., Peng, Shulin., Zhang, Xiaofeng. Chemical constituents of Meconopsis punicea. tianran chanwu yanjiu yu kaifa, 2011, vol. 23, no. 2, p. 202–207. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Substance:

berberine (RF-00003706-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

GC-MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

berberine in aerial parts

Composition #6: Wu, Haifeng., Song, Zhijun., Zhu, Huajie., Peng, Shulin., Zhang, Xiaofeng. Chemical constituents of Meconopsis punicea. tianran chanwu yanjiu yu kaifa, 2011, vol. 23, no. 2, p. 202–207. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Substance:

Karachine (RF-00011158-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

GC-MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Karachine in aerial parts

Composition #7: Wu, Haifeng., Song, Zhijun., Zhu, Huajie., Peng, Shulin., Zhang, Xiaofeng. Chemical constituents of Meconopsis punicea. tianran chanwu yanjiu yu kaifa, 2011, vol. 23, no. 2, p. 202–207. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Substance:

hydnocarpin (RF-00011070-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

GC-MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

hydnocarpin in aerial parts

Composition #8: Wu, Haifeng., Song, Zhijun., Zhu, Huajie., Peng, Shulin., Zhang, Xiaofeng. Chemical constituents of Meconopsis punicea. tianran chanwu yanjiu yu kaifa, 2011, vol. 23, no. 2, p. 202–207. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Substance:

protopine (RF-00004010-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

GC-MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

protopine in aerial parts

Composition #9: Yuan, CC., Nan, P., Shi, SH., Zhong, Y. Chemical composition of the essential oils of two Chinese endemic Meconopsis species. zeitschrift fur naturforschung c-a journal of biosciences, 2003, vol. 58, no. 5-6, p. 313–315. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

alpha-Hexylcinnamaldehyde (RF-00010108-PAR)
Additional substance description:

hexyl cinnamaldehyde
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.7
Internal remarks:

Hexyl cinnamaldehyde in whole plant

Composition #10: Yuan, CC., Nan, P., Shi, SH., Zhong, Y. Chemical composition of the essential oils of two Chinese endemic Meconopsis species. zeitschrift fur naturforschung c-a journal of biosciences, 2003, vol. 58, no. 5-6, p. 313–315. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Naphthalene derivatives (RF-00010833-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1-11.4
Internal remarks:

Naphthalene derivatives in whole plant

Composition #11: Shang, Xiaofei., Wang, Dongsheng., Miao, Xiaolou., Wang, Yu., Zhang, Jiyu., Wang, Xuezhi., Zhang, Yu., Pan, Hu. Antinociceptive and anti-tussive activities of the ethanol extract of the flowers of Meconopsis punicea Maxim. bmc complementary and alternative medicine, 2015, vol. 15 . DOI: 10.1186/s12906-015-0671-y. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol 95%
Substance:

berberine (RF-00003706-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Berberine in flowers