EFSA Compendium of Botanicals

Draft - work in progress

Haplophyllum dauricum (L.) G. Don // Haplophyllum dahuricum A.Juss.

Family:: Rutaceae
Approval state:: Approved
Number of articles retrieved:: 2
Number of processed references:: 2

Compositions

#1: gamma-fagarine and skimmianine #2: Umbelliferone and derivatives #3: justicidin B and daurinol #4: Scopolin and haploperoside A [(from H. perforatum) #5: Dauroside d (Coumarins) in Haplophyllum dauricum

Endpoint Studies

Genotoxicity

Composition #1: Batsuren, D., Batirov, E. Kh., Malikov, V. M. Coumarins from Haplophyllum dahuricum. khimiya prirodnykh soedinenii, 1981 . .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

gamma-fagarine and skimmianine
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

gamma-fagarine and skimmianine

Composition #2: Batsuren, D., Batirov, E. Kh., Malikov, V. M. Coumarins from Haplophyllum dahuricum. khimiya prirodnykh soedinenii, 1981 . .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

umbelliferone (RF-00004096-PAR)
Additional substance description:

umbelliferone and its 7-O-β-D-glucopyranoside
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Umbelliferone and derivatives

Composition #3: Batsuren, D., Batirov, E. Kh., Malikov, V. M. Coumarins from Haplophyllum dahuricum. khimiya prirodnykh soedinenii, 1981 . .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

justicidin B and daurinol
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

justicidin B and daurinol

Composition #4: Aminov, S. D., Vakhabov, A. A. Pharmacology of some coumarins isolated from the plant Haplophyllum. doklady akademii nauk uzssr, 1985, p. 44–45. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Additional extraction description:

unspecified
Substance:

coumarins (RF-00004351-PAR)
Additional substance description:

Scopolin and haploperoside A [(from H. perforatum)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Scopolin and haploperoside A [(from H. perforatum)

Composition #5: Aminov, S. D., Vakhabov, A. A. Pharmacology of some coumarins isolated from the plant Haplophyllum. doklady akademii nauk uzssr, 1985, p. 44–45. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Additional extraction description:

unspecified
Substance:

coumarins (RF-00004351-PAR)
Additional substance description:

dauroside D [(from H. dauricum)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Dauroside d (Coumarins) in Haplophyllum dauricum