EFSA Compendium of Botanicals

Draft - work in progress

Sarcocephalus pobeguinii Hua ex Pobég.

Family:: Rubiaceae
Approval state:: Approved
Number of articles retrieved:: 1
Number of processed references:: 1

Compositions

Endpoint Studies

Genotoxicity

Composition #1: Agnaniet, Huguette., Mbot, Elvis Jolinom., Keita, Ousmane., Fehrentz, Jean-Alain., Ankli, Anita., Gallud, Audrey., Garcia, Marcel., Gary-Bobo, Magali., Lebibi, Jacques., Cresteil, Thierry., Menut, Chantal. Antidiabetic potential of two medicinal plants used in Gabonese folk medicine.. bmc complementary and alternative medicine, 2016, vol. 16, no. 1, p. 71. DOI: 10.1186/s12906-016-1052-x. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water (decoction)
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids

Composition #2: Agnaniet, Huguette., Mbot, Elvis Jolinom., Keita, Ousmane., Fehrentz, Jean-Alain., Ankli, Anita., Gallud, Audrey., Garcia, Marcel., Gary-Bobo, Magali., Lebibi, Jacques., Cresteil, Thierry., Menut, Chantal. Antidiabetic potential of two medicinal plants used in Gabonese folk medicine.. bmc complementary and alternative medicine, 2016, vol. 16, no. 1, p. 71. DOI: 10.1186/s12906-016-1052-x. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water (decoction)
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Saponins

Endpoint study #1: Agnaniet, Huguette., Mbot, Elvis Jolinom., Keita, Ousmane., Fehrentz, Jean-Alain., Ankli, Anita., Gallud, Audrey., Garcia, Marcel., Gary-Bobo, Magali., Lebibi, Jacques., Cresteil, Thierry., Menut, Chantal. Antidiabetic potential of two medicinal plants used in Gabonese folk medicine.. bmc complementary and alternative medicine, 2016, vol. 16, no. 1, p. 71. DOI: 10.1186/s12906-016-1052-x. [DOI link]

Study relevance:

Human health
Plant part:

Bark (as part-nature) (A066X)
Preparation/Extraction method:

Solvent extraction (A0BZR)
Additional plant/substance description:

decoction
Type of toxicological test:

in vitro (CHD061TT)
Endpoint measured:

Enzyme inhibition (CHD067EP)
Concentration unit:

Milligram/millilitre (G191A)
Effect concentration:

1
Critical effect:

Digestive (TOX18A)
Target tissue:

digestive: Pancreas (TT024A)
Effect description:

beta-glucosidase inhibition
Effect or parameter linked to the endpoint:

enzyme inhibition (CHD032BE)
Internal remarks:

beta-glucosidase inhibition