EFSA Compendium of Botanicals

Draft - work in progress

Valeriana jatamansi Jones

Family:: Caprifoliaceae
Approval state:: Approved
Number of articles retrieved:: 517
Number of processed references:: 7

Compositions

#1: valerian m-phenoxy benzaldehyde (benzaldehyde) #2: lignans in whole plant #3: baldrinal and derivatives in rhizomes #4: 5-hydroxymethyl furfural in rhizomes #5: lignans in rhizomes #6: Coumarins in rhizome #7: lignans in roots #8: 7-epi-α-Selinene in roots #9: valtral A –C in whole plant #10: baldrinal and homobaldrinal in whole plant

Endpoint Studies

Genotoxicity

Composition #1: Wu, Dan., Wang, Baohua., Yan, Xingli., Shi, Jinli., Zhang, Xiaoru., Song, Ge. Extract technique of valerian m-phenoxy benzaldehyde from Valeriana jatamansi Jones. beijing zhongyiyao daxue xuebao, 2009, vol. 32, no. 7, p. 481–483. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol 70%
Substance:

Benzaldehyde (RF-00008323-PAR)
Additional substance description:

valerian m-phenoxy benzaldehyde
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

valerian m-phenoxy benzaldehyde (benzaldehyde)

Composition #2: Lin, Sheng., Chen, Tao., Liu, Xiao-Hua., Shen, Yun-Heng., Li, Hui-Liang., Shan, Lei., Liu, Run-Hui., Xu, Xi-Ke., Zhang, Wei-Dong., Wang, Hui. Iridoids and Lignans from Valeriana jatamansi. figshare, 2010 . DOI: http://dx.doi.org/10.1021/np900795c.s002. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol 95%
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

(+)-9′-isovaleroxylariciresinol and other 13 lignans
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

IR, MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

lignans in whole plant

Composition #3: Yong, Y., Huang, Q., Wang, R.-J., Li, H.-X., Zhang, H., Feng, W.-W., Yin, Z.-Q., Liu, Y., Fu, H.-Y., Tan, Y.-Z., Dong, X.-P. Chemical constituents from rhizomes of Valeriana jatamansi. chinese traditional and herbal drugs, 2015, vol. 46, no. 23, p. 3466–3470. DOI: 10.7501/j.issn.0253-2670.2015.23.004. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

baldrinal (RF-00004171-PAR)
Additional substance description:

vibutinal, baldrinal, 11-ethoxyviburtinal
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

ms
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

baldrinal and derivatives in rhizomes

Composition #4: Yong, Y., Huang, Q., Wang, R.-J., Li, H.-X., Zhang, H., Feng, W.-W., Yin, Z.-Q., Liu, Y., Fu, H.-Y., Tan, Y.-Z., Dong, X.-P. Chemical constituents from rhizomes of Valeriana jatamansi. chinese traditional and herbal drugs, 2015, vol. 46, no. 23, p. 3466–3470. DOI: 10.7501/j.issn.0253-2670.2015.23.004. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Hydroxymethylfurfural (RF-00000379-ORG)
Additional substance description:

5-hydroxymethyl furfural
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

ms
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

5-hydroxymethyl furfural in rhizomes

Composition #5: Yong, Y., Huang, Q., Wang, R.-J., Li, H.-X., Zhang, H., Feng, W.-W., Yin, Z.-Q., Liu, Y., Fu, H.-Y., Tan, Y.-Z., Dong, X.-P. Chemical constituents from rhizomes of Valeriana jatamansi. chinese traditional and herbal drugs, 2015, vol. 46, no. 23, p. 3466–3470. DOI: 10.7501/j.issn.0253-2670.2015.23.004. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

8-hydroxypinoresinol, pinoresinol, prinsepiol
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

ms
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

lignans in rhizomes

Composition #6: Mao, Cheng-dong., Song, Hui-zhu., Yang, Bo., Zhang, Jian-fen., Gu, Man-cang., Li, Yue-lan. Chemical Constituents from Rhizome of Valeriana jatamansi .. zhong yao cai = zhongyaocai = journal of chinese medicinal materials, 2015, vol. 38, no. 8, p. 1665–7. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

coumarins (RF-00004351-PAR)
Additional substance description:

decursidin, decursitin B, decursitin A, 3'(S)-acetoxy-4'(R)-angeloyloxy-3',4'-dihydroxanthyletin
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Coumarins in rhizome

Composition #7: Navarrete, A., Avula, B., Choi, YW., Khan, IA. Chemical fingerprinting of Valeriana species: Simultaneous determination of valerenic acids, flavonoids, and phenylpropanoids using liquid chromatography with ultraviolet detection . journal of aoac international, 2006, vol. 89, no. 1, p. 8–15. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

massoniresinol-4-O--D-glucoside, berchemol-4- O--D-glucoside, pinoresinol-4,4-di-O--D-glucoside, 8-hydroxypinoresinol-4-O--D-glucoside, pinoresinol4-O--D-glucoside
Analytical method code:

HPLC-DAD (F587A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

lignans in roots

Composition #8: Verma, Ram S., Padalia, Rajendra C., Chauhan, Amit. Assessment of similarities and dissimilarities in the essential oils of patchouli and Indian Valerian . journal of essential oil research, 2012, vol. 24, no. 5, p. 487–491. DOI: 10.1080/10412905.2012.705095. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts used as staple food (as part-nature) (A0F5F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

alpha-Selinene (RF-00010780-PAR)
Additional substance description:

7-epi-α-Selinene
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.5
Internal remarks:

7-epi-α-Selinene in roots

Composition #9: Lin, Sheng., Chen, Tao., Fu, Peng., Ye, Ji., Yang, Xian-Wen., Shan, Lei., Li, Hui-Liang., Liu, Run-Hui., Shen, Yun-Heng., Xu, Xi-Ke., Zhang, Wei-Dong. Three decomposition products of valepotriates from Valeriana jatamansi and their cytotoxic activity . journal of asian natural products research, 2015, vol. 17, no. 5, p. 455–461. DOI: 10.1080/10286020.2015.1041933. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol 95%
Substance:

furan derivatives (RF-00004396-PAR)
Additional substance description:

valtral A –C
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

MS, IR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

valtral A –C in whole plant

Composition #10: Lin, Sheng., Chen, Tao., Fu, Peng., Ye, Ji., Yang, Xian-Wen., Shan, Lei., Li, Hui-Liang., Liu, Run-Hui., Shen, Yun-Heng., Xu, Xi-Ke., Zhang, Wei-Dong. Three decomposition products of valepotriates from Valeriana jatamansi and their cytotoxic activity . journal of asian natural products research, 2015, vol. 17, no. 5, p. 455–461. DOI: 10.1080/10286020.2015.1041933. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol 95%
Substance:

baldrinal (RF-00004171-PAR)
Additional substance description:

baldrinal and homobaldrinal
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

MS, IR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

baldrinal and homobaldrinal in whole plant