Tylophora indica (Burm. f.) Merr.

Family:
Apocynaceae
Approval state:
Approved
Number of articles retrieved:
265
Number of processed references:
5
Compositions
#1: alkaloids in leaves #2: Tylophora alkaloids (tylophorinine, tylophorine, tylophorinidine) in unspecified part #3: saponins in leaves #4: tylophorine, tylophorinine, demethyltylophorine, 4- methoxy-14-hydroxytylophorine, acctyl-O-methyltylophorinidine/acetyltylophorinine, and d-septicine in aerial parts #5: phenanthroindolizidine alkaloids (tyloindicines A-E, tylophorine, tyloindicines F-J) in aerial parts
Endpoint Studies
Genotoxicity
Composition #1: Kathuria, Vanit., Kaushik, Nutan. Feeding inhibition of Helicoverpa armigera (Hubner) by Eucalyptus camaidulensis and Tylophora indica extracts . insect science, 2005, vol. 12, no. 4, p. 249–254. DOI: 10.1111/j.1005-295X.2005.00031.x. [DOI link]
Composition #2: Ganguly, T., Khar, A. Induction of apoptosis in a human erythroleukemic cell line K562 by Tylophora alkaloids involves release of cytochrome c and activation of caspase 3 . phytomedicine, 2002, vol. 9, no. 4, p. 288–295. DOI: 10.1078/0944-7113-00146. [DOI link]
Composition #3: Gujrati, Vipul., Patel, Nilesh., Rao, Venkat N., Nandakumar, K., Gouda, T. S., Shalam, Md., Kumar, S. M. Shanta. Hepatoprotective activity of alcoholic and aqueous extracts of leaves of Tylophora indica (Linn.) in rats . indian journal of pharmacology, 2007, vol. 39, no. 1, p. 43–47. .
Composition #4: BHUTANI, KK., SHARMA, GL., ALI, M. PLANT BASED ANTIAMOEBIC DRUGS .1. ANTIAMOEBIC ACTIVITY OF PHENANTHROINDOLIZIDINE ALKALOIDS - COMMON STRUCTURAL DETERMINANTS OF ACTIVITY WITH EMETINE . planta medica, 1987, vol. 53, no. 6, p. 532–536. DOI: 10.1055/s-2006-962803. [DOI link]
Composition #5: ALI, M., ANSARI, SH., QADRY, JS. RARE PHENANTHROINDOLIZIDINE ALKALOIDS AND A SUBSTITUTED PHENANTHRENE, TYLOINDANE, FROM TYLOPHORA-INDICA . journal of natural products, 1991, vol. 54, no. 5, p. 1271–1278. DOI: 10.1021/np50077a005. [DOI link]