EFSA
ecomole
vscht
  2. Tetradium ruticarpum (A. Juss.) T.G. Hartley // Evodia ruticarpa (A.Juss.) Hook.f. & Thomson

Tetradium ruticarpum (A. Juss.) T.G. Hartley // Evodia ruticarpa (A.Juss.) Hook.f. & Thomson

Family:
Rutaceae
Approval state:
Approved
Number of articles retrieved:
685
Number of processed references:
8
Compositions
#1: evodirutaenin A in fruits #2: shihulimonin A in fruits #3: limonin, fruit, HPLC #4: evodiamine, fruit, HPLC #5: rutaecarpine, fruit, HPLC #6: rutaecarpine #7: synephrine in fruits #8: rutaecarpine in fruits #9: evodiamine in fruits #10: evodiamine, fruit, NMR #11: rutaecarpine, fruit, NMR #12: quinolone alkaloids in fruits #13: Dehydroevodiamine in fruits #14: evodiamine, fruit,UHPLC #15: rutaecarpine, fruit,UHPLC #16: limonin, fruit, UHPLC #17: Dehydroevodiamine, fruit,UHPLC #18: Carboline alkaloids in fruit #19: Quinoline alkaloids in fruit #20: 6-acetoxy-5-epilimonin in fruit #21: Quinolone alkaloids in fruit
Endpoint Studies
#1: increase in liver enzymes, lung , kidney #2: Increase of serum levels of alanine transaminase (ALT), aspartate aminotransferase (AST) and liver coefficient as indices of liver injury.
Genotoxicity
Composition #1: Yang, Xiu-Wei., Teng, Jie. Chemical constituents of the unripe fruits of Evodia rutaecarpa. journal of chinese pharmaceutical sciences, 2007, vol. 16, no. 1, p. 20–23. .
Composition #2: Yang, Xiu-Wei., Teng, Jie. Chemical constituents of the unripe fruits of Evodia rutaecarpa. journal of chinese pharmaceutical sciences, 2007, vol. 16, no. 1, p. 20–23. .
Composition #3: Zhang, Hongmei., Wang, Changhong., Cheng, Xuemei., Wang, Zhengtao., Yue, Jianmin. Simultaneous determination of limonin, evodiamine and rutaecarpine in Fructus Evodiae by high-performance liquid chromatography. asian journal of traditional medicines, 2008, vol. 3, no. 5, p. 163–171. .
Composition #4: Zhang, Hongmei., Wang, Changhong., Cheng, Xuemei., Wang, Zhengtao., Yue, Jianmin. Simultaneous determination of limonin, evodiamine and rutaecarpine in Fructus Evodiae by high-performance liquid chromatography. asian journal of traditional medicines, 2008, vol. 3, no. 5, p. 163–171. .
Composition #5: Zhang, Hongmei., Wang, Changhong., Cheng, Xuemei., Wang, Zhengtao., Yue, Jianmin. Simultaneous determination of limonin, evodiamine and rutaecarpine in Fructus Evodiae by high-performance liquid chromatography. asian journal of traditional medicines, 2008, vol. 3, no. 5, p. 163–171. .
Composition #6: Ueng, YF., Tsai, TH., Don, MJ., Chen, RM., Chen, TL. Alteration of the pharmacokinetics of theophylline by rutaecarpine, an alkaloid of the medicinal herb Evodia rutaecarpa, in rats . journal of pharmacy and pharmacology, 2005, vol. 57, no. 2, p. 227–232. DOI: 10.1211/0022357055489. [DOI link]
Composition #7: Pellati, F., Benvenuti, S., Yoshizaki, F., Melegari, M. Development and validation of HPLC methods for the analysis of phenethylamine and indoloquinazoline alkaloids in Evodia species . journal of separation science, 2006, vol. 29, no. 5, p. 641–649. DOI: 10.1002/jssc.200500460. [DOI link]
Composition #8: Pellati, F., Benvenuti, S., Yoshizaki, F., Melegari, M. Development and validation of HPLC methods for the analysis of phenethylamine and indoloquinazoline alkaloids in Evodia species . journal of separation science, 2006, vol. 29, no. 5, p. 641–649. DOI: 10.1002/jssc.200500460. [DOI link]
Composition #9: Pellati, F., Benvenuti, S., Yoshizaki, F., Melegari, M. Development and validation of HPLC methods for the analysis of phenethylamine and indoloquinazoline alkaloids in Evodia species . journal of separation science, 2006, vol. 29, no. 5, p. 641–649. DOI: 10.1002/jssc.200500460. [DOI link]
Composition #10: Yang, X. -W., Zhang, H., Li, M., Du, L. -J., Yang, Z., Xiao, S. -Y. Studies on the alkaloid constituents of Evodia rutaecarpa (Juss) Benth var. bodinaieri (Dode) Huang and their acute toxicity in mice . journal of asian natural products research, 2006, vol. 8, no. 8, p. 697–703. DOI: 10.1080/10286020412331286425. [DOI link]
Composition #11: Yang, X. -W., Zhang, H., Li, M., Du, L. -J., Yang, Z., Xiao, S. -Y. Studies on the alkaloid constituents of Evodia rutaecarpa (Juss) Benth var. bodinaieri (Dode) Huang and their acute toxicity in mice . journal of asian natural products research, 2006, vol. 8, no. 8, p. 697–703. DOI: 10.1080/10286020412331286425. [DOI link]
Composition #12: Yang, X. -W., Zhang, H., Li, M., Du, L. -J., Yang, Z., Xiao, S. -Y. Studies on the alkaloid constituents of Evodia rutaecarpa (Juss) Benth var. bodinaieri (Dode) Huang and their acute toxicity in mice . journal of asian natural products research, 2006, vol. 8, no. 8, p. 697–703. DOI: 10.1080/10286020412331286425. [DOI link]
Composition #13: Schramm, Anja., Hamburger, Matthias. Gram-scale purification of dehydroevodiamine from Evodia rutaecarpa fruits, and a procedure for selective removal of quaternary indoloquinazoline alkaloids from Evodia extracts . fitoterapia, 2014, vol. 94, p. 127–133. DOI: 10.1016/j.fitote.2014.02.005. [DOI link]
Composition #14: Zhao, Yang., Zhao, Yunling., Zhou, Xin., Gong, Xiaojian. Development and validation of an UPLC-ESI-MS/MS method for determination of dehydroevodiamine, limonin, evodiamine, and rutaecarpine in Evodiae Fructus . pharmacognosy magazine, 2014, vol. 10, no. 39, p. 374–383. DOI: 10.4103/0973-1296.137381. [DOI link]
Composition #15: Zhao, Yang., Zhao, Yunling., Zhou, Xin., Gong, Xiaojian. Development and validation of an UPLC-ESI-MS/MS method for determination of dehydroevodiamine, limonin, evodiamine, and rutaecarpine in Evodiae Fructus . pharmacognosy magazine, 2014, vol. 10, no. 39, p. 374–383. DOI: 10.4103/0973-1296.137381. [DOI link]
Composition #16: Zhao, Yang., Zhao, Yunling., Zhou, Xin., Gong, Xiaojian. Development and validation of an UPLC-ESI-MS/MS method for determination of dehydroevodiamine, limonin, evodiamine, and rutaecarpine in Evodiae Fructus . pharmacognosy magazine, 2014, vol. 10, no. 39, p. 374–383. DOI: 10.4103/0973-1296.137381. [DOI link]
Composition #17: Zhao, Yang., Zhao, Yunling., Zhou, Xin., Gong, Xiaojian. Development and validation of an UPLC-ESI-MS/MS method for determination of dehydroevodiamine, limonin, evodiamine, and rutaecarpine in Evodiae Fructus . pharmacognosy magazine, 2014, vol. 10, no. 39, p. 374–383. DOI: 10.4103/0973-1296.137381. [DOI link]
Composition #18: Li, Wenlan., Sun, Xiangming., Liu, Bingmei., Zhang, Lihui., Fan, Ziquan., Ji, Yubin. Screening and identification of hepatotoxic component in Evodia rutaecarpa based on spectrum-effect relationship and UPLC-Q-TOFMS . biomedical chromatography, 2016, vol. 30, no. 12, p. 1975–1983. DOI: 10.1002/bmc.3774. [DOI link]
Composition #19: Li, Wenlan., Sun, Xiangming., Liu, Bingmei., Zhang, Lihui., Fan, Ziquan., Ji, Yubin. Screening and identification of hepatotoxic component in Evodia rutaecarpa based on spectrum-effect relationship and UPLC-Q-TOFMS . biomedical chromatography, 2016, vol. 30, no. 12, p. 1975–1983. DOI: 10.1002/bmc.3774. [DOI link]
Composition #20: Li, Wenlan., Sun, Xiangming., Liu, Bingmei., Zhang, Lihui., Fan, Ziquan., Ji, Yubin. Screening and identification of hepatotoxic component in Evodia rutaecarpa based on spectrum-effect relationship and UPLC-Q-TOFMS . biomedical chromatography, 2016, vol. 30, no. 12, p. 1975–1983. DOI: 10.1002/bmc.3774. [DOI link]
Composition #21: Li, Wenlan., Sun, Xiangming., Liu, Bingmei., Zhang, Lihui., Fan, Ziquan., Ji, Yubin. Screening and identification of hepatotoxic component in Evodia rutaecarpa based on spectrum-effect relationship and UPLC-Q-TOFMS . biomedical chromatography, 2016, vol. 30, no. 12, p. 1975–1983. DOI: 10.1002/bmc.3774. [DOI link]
Endpoint study #1: Ueng, YF., Tsai, TH., Don, MJ., Chen, RM., Chen, TL. Alteration of the pharmacokinetics of theophylline by rutaecarpine, an alkaloid of the medicinal herb Evodia rutaecarpa, in rats . journal of pharmacy and pharmacology, 2005, vol. 57, no. 2, p. 227–232. DOI: 10.1211/0022357055489. [DOI link]
Endpoint study #2: Li, Wenlan., Sun, Xiangming., Liu, Bingmei., Zhang, Lihui., Fan, Ziquan., Ji, Yubin. Screening and identification of hepatotoxic component in Evodia rutaecarpa based on spectrum-effect relationship and UPLC-Q-TOFMS . biomedical chromatography, 2016, vol. 30, no. 12, p. 1975–1983. DOI: 10.1002/bmc.3774. [DOI link]