EFSA Compendium of Botanicals

Draft - work in progress

Tagetes erecta L. // Tagetes patula L.

Family:: Asteraceae
Approval state:: Approved
Number of articles retrieved:: 2777
Number of processed references:: 3

Compositions

#1: 5-hydroxymethylfurfural in root #2: alpha-terthienyl in root #3: 2-furaldehyde in root #4: 1,4-naphthoquinone (flowers) #5: Piperitenone (flowers) #6: Piperitone (flowers) #7: Menthone (flowers) #8: verbenone in leaves #9: ocimenone in leaves #10: tagetone and dihydrotagetone in leaves #11: piperitenone in leaves #12: piperitone in leaves

Endpoint Studies

Genotoxicity

Composition #1: Kumar, A., Chahal, K.K., Kataria, D. Comparison of chemical composition of root and rhizosphere soil extracts of Tagetes patula L.: GC-MS analysis. asian journal of chemistry, 2017, vol. 29, no. 4, p. 797–800. DOI: 10.14233/ajchem.2017.20307. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Hydroxymethylfurfural (RF-00000379-ORG)
Additional substance description:

5-Hydroxymethylfurfural
Analytical method code:

GC-MS (F046A)
Result unit:

Percent Area (G139A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

21.81
Internal remarks:

5-hydroxymethylfurfural in root

Composition #2: Kumar, A., Chahal, K.K., Kataria, D. Comparison of chemical composition of root and rhizosphere soil extracts of Tagetes patula L.: GC-MS analysis. asian journal of chemistry, 2017, vol. 29, no. 4, p. 797–800. DOI: 10.14233/ajchem.2017.20307. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

alpha-terthienyl (RF-00004139-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent Area (G139A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.86
Internal remarks:

alpha-terthienyl in root

Composition #3: Kumar, A., Chahal, K.K., Kataria, D. Comparison of chemical composition of root and rhizosphere soil extracts of Tagetes patula L.: GC-MS analysis. asian journal of chemistry, 2017, vol. 29, no. 4, p. 797–800. DOI: 10.14233/ajchem.2017.20307. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Furfural (RF-1009-001-PPP)
Additional substance description:

2-furaldehyde (synonym)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent Area (G139A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.87
Internal remarks:

2-furaldehyde in root

Composition #4: Martinez, Rossana., Diaz, Beth., Vasquez, Luis., Compagnone, Reinaldo S., Tillett, Stephen., Canelon, Dilsia J., Torrico, Fatima., Suarez, Alirica I. Chemical Composition of Essential Oils and Toxicological evaluation of Tagetes erecta and Tagetes patula from Venezuela . journal of essential oil bearing plants, 2009, vol. 12, no. 4, p. 476–481. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

distilled water
Substance:

1,4-naphthoquinone (RF-00006469-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

6.5
Internal remarks:

1,4-naphthoquinone (flowers)

Composition #5: Martinez, Rossana., Diaz, Beth., Vasquez, Luis., Compagnone, Reinaldo S., Tillett, Stephen., Canelon, Dilsia J., Torrico, Fatima., Suarez, Alirica I. Chemical Composition of Essential Oils and Toxicological evaluation of Tagetes erecta and Tagetes patula from Venezuela . journal of essential oil bearing plants, 2009, vol. 12, no. 4, p. 476–481. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

distilled water
Substance:

p-Mentha-1,4(8)-dien-3-one (RF-00009950-PAR)
Additional substance description:

Piperitenone
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

4.8
Internal remarks:

Piperitenone (flowers)

Composition #6: Martinez, Rossana., Diaz, Beth., Vasquez, Luis., Compagnone, Reinaldo S., Tillett, Stephen., Canelon, Dilsia J., Torrico, Fatima., Suarez, Alirica I. Chemical Composition of Essential Oils and Toxicological evaluation of Tagetes erecta and Tagetes patula from Venezuela . journal of essential oil bearing plants, 2009, vol. 12, no. 4, p. 476–481. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

distilled water
Substance:

l-Piperitone (RF-00007699-PAR)
Additional substance description:

Piperitone
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

13.4
Internal remarks:

Piperitone (flowers)

Composition #7: Martinez, Rossana., Diaz, Beth., Vasquez, Luis., Compagnone, Reinaldo S., Tillett, Stephen., Canelon, Dilsia J., Torrico, Fatima., Suarez, Alirica I. Chemical Composition of Essential Oils and Toxicological evaluation of Tagetes erecta and Tagetes patula from Venezuela . journal of essential oil bearing plants, 2009, vol. 12, no. 4, p. 476–481. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

distilled water
Substance:

menthone (RF-00011280-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.2
Internal remarks:

Menthone (flowers)

Composition #8: de Oliveira, Pollyanna Francielli., Alves, Jacqueline Morais., Damasceno, Jaqueline Lopes., Machado Oliveira, Renata Aparecida., Dias, Herbert Junior., Miller Crotti, Antonio Eduardo., Tavares, Denise Crispim. Cytotoxicity screening of essential oils in cancer cell lines. revista brasileira de farmacognosia-brazilian journal of pharmacognosy, 2015, vol. 25, no. 2, p. 183–188. DOI: 10.1016/j.bjp.2015.02.009. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

Verbenone (RF-00010114-PAR)
Analytical method code:

Gaschromatography (GC) (F037A)
Analytical method - additional description:

the percentage is relative area (peak area relative to the total peak area in the GC-FID chromatogram)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

9.7
Internal remarks:

verbenone in leaves

Composition #9: de Oliveira, Pollyanna Francielli., Alves, Jacqueline Morais., Damasceno, Jaqueline Lopes., Machado Oliveira, Renata Aparecida., Dias, Herbert Junior., Miller Crotti, Antonio Eduardo., Tavares, Denise Crispim. Cytotoxicity screening of essential oils in cancer cell lines. revista brasileira de farmacognosia-brazilian journal of pharmacognosy, 2015, vol. 25, no. 2, p. 183–188. DOI: 10.1016/j.bjp.2015.02.009. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

Cis-Ocimenone (RF-00011467-PAR)
Additional substance description:

ocimenone
Analytical method code:

Gaschromatography (GC) (F037A)
Analytical method - additional description:

the percentage is relative area (peak area relative to the total peak area in the GC-FID chromatogram)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

13.0
Internal remarks:

ocimenone in leaves

Composition #10: de Oliveira, Pollyanna Francielli., Alves, Jacqueline Morais., Damasceno, Jaqueline Lopes., Machado Oliveira, Renata Aparecida., Dias, Herbert Junior., Miller Crotti, Antonio Eduardo., Tavares, Denise Crispim. Cytotoxicity screening of essential oils in cancer cell lines. revista brasileira de farmacognosia-brazilian journal of pharmacognosy, 2015, vol. 25, no. 2, p. 183–188. DOI: 10.1016/j.bjp.2015.02.009. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

tagetone (RF-00003596-PAR)
Additional substance description:

and dihydrotagetone
Analytical method code:

Gaschromatography (GC) (F037A)
Analytical method - additional description:

the percentage is relative area (peak area relative to the total peak area in the GC-FID chromatogram)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

6.9-11.8
Internal remarks:

tagetone and dihydrotagetone in leaves

Composition #11: de Oliveira, Pollyanna Francielli., Alves, Jacqueline Morais., Damasceno, Jaqueline Lopes., Machado Oliveira, Renata Aparecida., Dias, Herbert Junior., Miller Crotti, Antonio Eduardo., Tavares, Denise Crispim. Cytotoxicity screening of essential oils in cancer cell lines. revista brasileira de farmacognosia-brazilian journal of pharmacognosy, 2015, vol. 25, no. 2, p. 183–188. DOI: 10.1016/j.bjp.2015.02.009. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

p-Mentha-1,4(8)-dien-3-one (RF-00009950-PAR)
Additional substance description:

piperitenone
Analytical method code:

Mass Spectroscopy and hyphenated methods without chromatography (F063A)
Analytical method - additional description:

the percentage is relative area (peak area relative to the total peak area in the GC-FID chromatogram)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

9.7
Internal remarks:

piperitenone in leaves

Composition #12: de Oliveira, Pollyanna Francielli., Alves, Jacqueline Morais., Damasceno, Jaqueline Lopes., Machado Oliveira, Renata Aparecida., Dias, Herbert Junior., Miller Crotti, Antonio Eduardo., Tavares, Denise Crispim. Cytotoxicity screening of essential oils in cancer cell lines. revista brasileira de farmacognosia-brazilian journal of pharmacognosy, 2015, vol. 25, no. 2, p. 183–188. DOI: 10.1016/j.bjp.2015.02.009. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

l-Piperitone (RF-00007699-PAR)
Analytical method code:

Mass Spectroscopy and hyphenated methods without chromatography (F063A)
Analytical method - additional description:

the percentage is relative area (peak area relative to the total peak area in the GC-FID chromatogram)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

8.8
Internal remarks:

piperitone in leaves