Draft - work in progress
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- Styphnolobium japonicum (L.) Schott // Sophora japonica L.
Styphnolobium japonicum (L.) Schott // Sophora japonica L.
- Family:
- Fabaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 2973
- Number of processed references:
- 5
Composition #1: Mazur, Witold M., Duke, James A., Wahala, Kristiina., Rasku, Sirpa., Adlercreutz, Herman. Isoflavonoids and lignans in legumes: nutritional and health aspects in humans. journal of nutritional biochemistry, 1998, vol. 9, no. 4, p. 193–200. .
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-
Plant part:
Unspecified (A07XD)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
diethyl ether
-
Substance:
genistein (RF-00000297-NTR)
-
Analytical method code:
GC-MS (F046A)
-
Result unit:
Microgram/100 gram (G046A)
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Result type:
Numerical Value (VAL)
-
Value (concentration, content):
265.0
-
Internal remarks:
genistein in unspecified part
Composition #2: Mazur, Witold M., Duke, James A., Wahala, Kristiina., Rasku, Sirpa., Adlercreutz, Herman. Isoflavonoids and lignans in legumes: nutritional and health aspects in humans. journal of nutritional biochemistry, 1998, vol. 9, no. 4, p. 193–200. .
-
-
Plant part:
Unspecified (A07XD)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
diethyl ether
-
Substance:
matairesinol (RF-00000331-NTR)
-
Analytical method code:
GC-MS (F046A)
-
Result unit:
Microgram/100 gram (G046A)
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Result type:
Numerical Value (VAL)
-
Value (concentration, content):
3.8
-
Internal remarks:
matairesinol in unspecified part
Composition #3: Mazur, Witold M., Duke, James A., Wahala, Kristiina., Rasku, Sirpa., Adlercreutz, Herman. Isoflavonoids and lignans in legumes: nutritional and health aspects in humans. journal of nutritional biochemistry, 1998, vol. 9, no. 4, p. 193–200. .
-
-
Plant part:
Unspecified (A07XD)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
diethyl ether
-
Substance:
daidzein (RF-00000061-NTR)
-
Analytical method code:
GC-MS (F046A)
-
Result unit:
Microgram/100 gram (G046A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
319.0
-
Internal remarks:
daidzein in unspecified part
Composition #4: Mazur, Witold M., Duke, James A., Wahala, Kristiina., Rasku, Sirpa., Adlercreutz, Herman. Isoflavonoids and lignans in legumes: nutritional and health aspects in humans. journal of nutritional biochemistry, 1998, vol. 9, no. 4, p. 193–200. .
-
-
Plant part:
Unspecified (A07XD)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
diethyl ether
-
Substance:
formononetin (RF-00000291-NTR)
-
Analytical method code:
GC-MS (F046A)
-
Result unit:
Microgram/100 gram (G046A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
322.0
-
Internal remarks:
formononetin in unspecified part
Composition #5: Mazur, Witold M., Duke, James A., Wahala, Kristiina., Rasku, Sirpa., Adlercreutz, Herman. Isoflavonoids and lignans in legumes: nutritional and health aspects in humans. journal of nutritional biochemistry, 1998, vol. 9, no. 4, p. 193–200. .
-
-
Plant part:
Unspecified (A07XD)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
diethyl ether
-
Substance:
coumestrol (RF-00000055-NTR)
-
Analytical method code:
GC-MS (F046A)
-
Result unit:
Microgram/100 gram (G046A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
9.9
-
Internal remarks:
coumestrol in unspecified part
Composition #6: Mazur, Witold M., Duke, James A., Wahala, Kristiina., Rasku, Sirpa., Adlercreutz, Herman. Isoflavonoids and lignans in legumes: nutritional and health aspects in humans. journal of nutritional biochemistry, 1998, vol. 9, no. 4, p. 193–200. .
-
-
Plant part:
Unspecified (A07XD)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
diethyl ether
-
Substance:
biochanin-A (RF-00004182-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Microgram/100 gram (G046A)
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Result type:
Numerical Value (VAL)
-
Value (concentration, content):
830.0
-
Internal remarks:
biochanin A in unspecified part
Composition #7: Mazur, Witold M., Duke, James A., Wahala, Kristiina., Rasku, Sirpa., Adlercreutz, Herman. Isoflavonoids and lignans in legumes: nutritional and health aspects in humans. journal of nutritional biochemistry, 1998, vol. 9, no. 4, p. 193–200. .
-
-
Plant part:
Unspecified (A07XD)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
diethyl ether
-
Substance:
lignans (RF-00004361-PAR)
-
Additional substance description:
anhydrosecoisolariciresinol and secoisolariciresinol
-
Analytical method code:
GC-MS (F046A)
-
Result unit:
Microgram/100 gram (G046A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
1590
-
Internal remarks:
lignans (anhydrosecoisolariciresinol and secoisolariciresinol) in unspecified part
Composition #8: Tang, Yuping., Lou, Fengchang., Wang, Jinghua. Isoflavonoids from the peel of Sophora japonica. zhongcaoyao, 2002, vol. 33, no. 1, p. 20–21. .
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-
Plant part:
Fruit peel (as part-nature) (A067G)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Substance:
isoflavones (RF-00004359-PAR)
-
Additional substance description:
e.g. pseudobaptigenin, prunetin
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Analytical method - additional description:
IR, 1H-NMR, 13C- NMR, and mass spectroscopy
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Isoflavones in peel
Composition #9: Tang, Yuping., Lou, Fengchang., Wang, Jinghua. Isoflavonoids from the peel of Sophora japonica. zhongcaoyao, 2002, vol. 33, no. 1, p. 20–21. .
-
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Substance:
daidzein (RF-00000061-NTR)
-
Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
-
Analytical method - additional description:
IR, 1H-NMR, 13C- NMR, and mass spectroscopy
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Daidzein in peel
Composition #10: Tang, Yuping., Lou, Fengchang., Wang, Jinghua. Isoflavonoids from the peel of Sophora japonica. zhongcaoyao, 2002, vol. 33, no. 1, p. 20–21. .
-
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Substance:
formononetin (RF-00000291-NTR)
-
Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
-
Analytical method - additional description:
IR, 1H-NMR, 13C- NMR, and mass spectroscopy
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Formononetin in peel
Composition #11: Tang, Yuping., Lou, Fengchang., Wang, Jinghua. Isoflavonoids from the peel of Sophora japonica. zhongcaoyao, 2002, vol. 33, no. 1, p. 20–21. .
-
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Substance:
genistein (RF-00000297-NTR)
-
Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
-
Analytical method - additional description:
IR, 1H-NMR, 13C- NMR, and mass spectroscopy
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Genistein in peel
Composition #12: Tang, Yuping., Lou, Fengchang., Wang, Jinghua. Isoflavonoids from the peel of Sophora japonica. zhongcaoyao, 2002, vol. 33, no. 1, p. 20–21. .
-
-
Plant part:
Fruit peel (as part-nature) (A067G)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Substance:
Prunetin (RF-00011016-PAR)
-
Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
-
Analytical method - additional description:
IR, 1H-NMR, 13C- NMR, and mass spectroscopy
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Prunetin in peel
Composition #13: Abdallah, Hossam M., Al-Abd, Ahmed M., Asaad, Gihan F., Abdel-Naim, Ashraf B., El-halawany, Ali M. Isolation of antiosteoporotic compounds from seeds of Sophora japonica.. plos one, 2014, vol. 9, no. 6, p. e98559. DOI: 10.1371/journal.pone.0098559.
[
DOI link]
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Plant part:
Seed (as part-nature) (A066P)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Methanol
-
Substance:
genistein (RF-00000297-NTR)
-
Additional substance description:
genistein 7,4’-di-O-b-D-glucopyransoide
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
genistein 7,4’-di-O-b-D-glucopyransoide in seeds
Composition #14: Abdallah, Hossam M., Al-Abd, Ahmed M., Asaad, Gihan F., Abdel-Naim, Ashraf B., El-halawany, Ali M. Isolation of antiosteoporotic compounds from seeds of Sophora japonica.. plos one, 2014, vol. 9, no. 6, p. e98559. DOI: 10.1371/journal.pone.0098559.
[
DOI link]
-
-
Plant part:
Seed (as part-nature) (A066P)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Methanol
-
Substance:
genistin (RF-00003829-PAR)
-
Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
genistin in seeds
Composition #15: Abdallah, Hossam M., Al-Abd, Ahmed M., Asaad, Gihan F., Abdel-Naim, Ashraf B., El-halawany, Ali M. Isolation of antiosteoporotic compounds from seeds of Sophora japonica.. plos one, 2014, vol. 9, no. 6, p. e98559. DOI: 10.1371/journal.pone.0098559.
[
DOI link]
-
-
Plant part:
Seed (as part-nature) (A066P)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Methanol
-
Substance:
isoflavones (RF-00004359-PAR)
-
Additional substance description:
sophorabioside
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
sophorabioside in seeds
Composition #16: Abdallah, Hossam M., Al-Abd, Ahmed M., Asaad, Gihan F., Abdel-Naim, Ashraf B., El-halawany, Ali M. Isolation of antiosteoporotic compounds from seeds of Sophora japonica.. plos one, 2014, vol. 9, no. 6, p. e98559. DOI: 10.1371/journal.pone.0098559.
[
DOI link]
-
-
Plant part:
Seed (as part-nature) (A066P)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Methanol
-
Substance:
Sophoricoside (RF-00011011-PAR)
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
sophoricoside in seeds
Composition #17: Min, B., Oh, SR., Lee, HK., Takatsu, K., Chang, IM., Min, KR., Kim, Y. Sophoricoside analogs as the IL-5 inhibitors from Sophora japonica. planta medica, 1999, vol. 65, no. 5, p. 408–412. DOI: 10.1055/s-1999-14016.
[
DOI link]
-
-
Plant part:
Fruit unspecified (as part-nature) (A067D)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
MeOH 80%
-
Substance:
genistin (RF-00003829-PAR)
-
Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
-
Analytical method - additional description:
ms, uv, ir
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
genistin in fruits
Composition #18: Min, B., Oh, SR., Lee, HK., Takatsu, K., Chang, IM., Min, KR., Kim, Y. Sophoricoside analogs as the IL-5 inhibitors from Sophora japonica. planta medica, 1999, vol. 65, no. 5, p. 408–412. DOI: 10.1055/s-1999-14016.
[
DOI link]
-
-
Plant part:
Fruit unspecified (as part-nature) (A067D)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
MeOH 80%
-
Substance:
isoflavones (RF-00004359-PAR)
-
Additional substance description:
orobol
-
Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
-
Analytical method - additional description:
uv, ir, ms
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
orobol in fruits
Composition #19: Min, B., Oh, SR., Lee, HK., Takatsu, K., Chang, IM., Min, KR., Kim, Y. Sophoricoside analogs as the IL-5 inhibitors from Sophora japonica. planta medica, 1999, vol. 65, no. 5, p. 408–412. DOI: 10.1055/s-1999-14016.
[
DOI link]
-
-
Plant part:
Fruit unspecified (as part-nature) (A067D)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
MeOH 80%
-
Substance:
genistein (RF-00000297-NTR)
-
Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
-
Analytical method - additional description:
ms, uv, ir
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
genistein in fruits
Composition #20: Min, B., Oh, SR., Lee, HK., Takatsu, K., Chang, IM., Min, KR., Kim, Y. Sophoricoside analogs as the IL-5 inhibitors from Sophora japonica. planta medica, 1999, vol. 65, no. 5, p. 408–412. DOI: 10.1055/s-1999-14016.
[
DOI link]
-
-
Plant part:
Fruit unspecified (as part-nature) (A067D)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
MeOH 80%
-
Substance:
Sophoricoside (RF-00011011-PAR)
-
Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
-
Analytical method - additional description:
uv, ir, ms
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
sophoricoside in fruits
Genotox #1: YIN, XJ., LIU, DX., WANG, HC., ZHOU, Y. A STUDY ON THE MUTAGENICITY OF 102 RAW PHARMACEUTICALS USED IN CHINESE TRADITIONAL MEDICINE . mutation research, 1991, vol. 260, no. 1, p. 73–82. .
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Study category:
Mutagenicity
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Type of toxicological test:
bacterial forward mutation assay (CHD026TT)
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-
Tested organism:
Salmonella typhimurium (as organism) (A0CPZ)
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Strain of test organism:
TA 98 (CHD029ST)
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-
Exogenous metabolic activation applied:
with and without
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-
Endpoint measured:
gene mutation
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-
Remarks on genotox study:
Sophora japonica L. was found to significantly induce His + revertants in Salmonella typhimurium strain TA98
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Internal remarks:
Sophora japonica L. was found to significantly induce His + revertants in Salmonella typhimurium TA98
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Internal ID:
WOS:A1991FK36700010