EFSA Compendium of Botanicals

Draft - work in progress

Strophanthus kombe Oliv.

Family:: Apocynaceae
Approval state:: Approved
Number of articles retrieved:: 93
Number of processed references:: 2

Compositions

#1: Cardenolides in seeds #2: Cardenolides in seeds

Endpoint Studies

Genotoxicity

Composition #1: Makarevich, I. F. Cardenolides of Strophanthus kombe. II. khimiya prirodnykh soedinenii, 1972, vol. (2), p. 180–8. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

defatting with petroleum ether, then extraction with 96% and 70% ethanol
Substance:

cardenolides (RF-00004389-PAR)
Additional substance description:

more than 30 derivatives (e.g. periploeymarin, cymarin, periplocin, k-strophanthin, erysimoside, k-strophanthoside )
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Analytical method - additional description:

UV, melting point, hydrolysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Cardenolides in seeds

Composition #2: Knittel, Diana N., Lorenz, Peter., Huber, Ursula., Stintzing, Florian C., Kammerer, Dietmar R. Characterization of the cardiac glycoside and lipid profiles of Strophanthus kombe Oliv. seeds . zeitschrift fur naturforschung section c-a journal of biosciences, 2016, vol. 71, no. 3-4, p. 55–64. DOI: 10.1515/znc-2015-0186. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water, ethanol-water (70:30, v/v), and ethyl acetate
Substance:

cardenolides (RF-00004389-PAR)
Additional substance description:

more than 20 substances
Analytical method code:

HPLC-DAD (F587A)
Analytical method - additional description:

actually: HPLC-DAD-MS/MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Cardenolides in seeds
completed:

True