EFSA Compendium of Botanicals

Draft - work in progress

Steganotaenia araliacea Hochst.

Family:: Apiaceae
Approval state:: Approved
Number of articles retrieved:: 81
Number of processed references:: 5

Compositions

#1: coumarins in roots #2: saponins in seeds #3: alkaloids in seeds #4: cardenolides in seeds #5: coumarines in seeds #6: scoparone in seeds #7: apiole in seeds #8: myristicin in seeds #9: prestegane B #10: 10-demethoxystegane #11: steganone #12: steganol #13: steganangin, episteganangin, steganoate A, steganoate B, steganolide in stem bark #14: steganacin in stem bark

Endpoint Studies

Genotoxicity

Composition #1: Oryema, Christine., Ziraba, Remigius Bukenya., Odyek, Olwa., Omagor, Nelson., Opio, Alfonse. Phytochemical properties and toxicity to brine shrimp of medicinal plants in Erute county, Lira district, Uganda. journal of medicinal plants research, 2011, vol. 5, no. 22, p. 5450–5457. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

coumarins (RF-00004351-PAR)
Additional substance description:

methanol, ether, water
Analytical method - additional description:

extraction
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

coumarins in roots

Composition #2: Demoz, Mussie Sium., Gachoki, Kareru Patrick., Mungai, Keriko Joseph., Negusse, Berhane Girmay. GC-MS analysis of the essential oil and methanol extract of the seeds of Steganotaenia araliacea hochst. american journal of plant sciences, 2014, vol. 5, no. 26), 3752-376, p. 10 pp. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Saponins (RF-00004333-PAR)
Analytical method - additional description:

Foam test/Froth test
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

saponins in seeds

Composition #3: Demoz, Mussie Sium., Gachoki, Kareru Patrick., Mungai, Keriko Joseph., Negusse, Berhane Girmay. GC-MS analysis of the essential oil and methanol extract of the seeds of Steganotaenia araliacea hochst. american journal of plant sciences, 2014, vol. 5, no. 26), 3752-376, p. 10 pp. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method - additional description:

Dragendroff’s test/Mayer’s test
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

alkaloids in seeds

Composition #4: Demoz, Mussie Sium., Gachoki, Kareru Patrick., Mungai, Keriko Joseph., Negusse, Berhane Girmay. GC-MS analysis of the essential oil and methanol extract of the seeds of Steganotaenia araliacea hochst. american journal of plant sciences, 2014, vol. 5, no. 26), 3752-376, p. 10 pp. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

cardenolides (RF-00004389-PAR)
Analytical method - additional description:

Keller Kiliani’s test
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

cardenolides in seeds

Composition #5: Demoz, Mussie Sium., Gachoki, Kareru Patrick., Mungai, Keriko Joseph., Negusse, Berhane Girmay. GC-MS analysis of the essential oil and methanol extract of the seeds of Steganotaenia araliacea hochst. american journal of plant sciences, 2014, vol. 5, no. 26), 3752-376, p. 10 pp. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

coumarins (RF-00004351-PAR)
Analytical method - additional description:

Alcoholic sodium hydroxide
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

coumarines in seeds

Composition #6: Demoz, Mussie Sium., Gachoki, Kareru Patrick., Mungai, Keriko Joseph., Negusse, Berhane Girmay. GC-MS analysis of the essential oil and methanol extract of the seeds of Steganotaenia araliacea hochst. american journal of plant sciences, 2014, vol. 5, no. 26), 3752-376, p. 10 pp. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

scoparone (RF-00004047-PAR)
Analytical method code:

GC-MS (F046A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

scoparone in seeds

Composition #7: Demoz, Mussie Sium., Gachoki, Kareru Patrick., Mungai, Keriko Joseph., Negusse, Berhane Girmay. GC-MS analysis of the essential oil and methanol extract of the seeds of Steganotaenia araliacea hochst. american journal of plant sciences, 2014, vol. 5, no. 26), 3752-376, p. 10 pp. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

apiole (RF-00003690-PAR)
Analytical method code:

GC-MS (F046A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

apiole in seeds

Composition #8: Demoz, Mussie Sium., Gachoki, Kareru Patrick., Mungai, Keriko Joseph., Negusse, Berhane Girmay. GC-MS analysis of the essential oil and methanol extract of the seeds of Steganotaenia araliacea hochst. american journal of plant sciences, 2014, vol. 5, no. 26), 3752-376, p. 10 pp. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

myristicin (RF-00003941-PAR)
Analytical method code:

GC-MS (F046A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

myristicin in seeds

Composition #9: Meragelman, KM., McKee, TC., Boyd, MR. 10-demethoxystegane, a new lignan from Steganotaenia araliacea. journal of natural products, 2001, vol. 64, no. 11, p. 1480–1482. DOI: 10.1021/np010248h. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified solvent
Substance:

prestegane B (RF-00004006-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

prestegane B

Composition #10: Meragelman, KM., McKee, TC., Boyd, MR. 10-demethoxystegane, a new lignan from Steganotaenia araliacea. journal of natural products, 2001, vol. 64, no. 11, p. 1480–1482. DOI: 10.1021/np010248h. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified solvent
Substance:

10-demethoxystegane (RF-00003606-PAR)
Analytical method code:

HPLC-UV (F021A)
Analytical method - additional description:

UV, IR, NMR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

10-demethoxystegane

Composition #11: Meragelman, KM., McKee, TC., Boyd, MR. 10-demethoxystegane, a new lignan from Steganotaenia araliacea. journal of natural products, 2001, vol. 64, no. 11, p. 1480–1482. DOI: 10.1021/np010248h. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified solvent
Substance:

steganone (RF-00004064-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

steganone

Composition #12: KUPCHAN, SM., BRITTON, RW., ZIEGLER, MF., GILMORE, CJ., RESTIVO, RJ., BRYAN, RF. TUMOR INHIBITORS .80. STEGANACIN AND STEGANANGIN, NOVEL ANTILEUKEMIC LIGNAN LACTONES FROM STEGANOTAENIA-ARALIACEA . journal of the american chemical society, 1973, vol. 95, no. 4, p. 1335–1336. DOI: 10.1021/ja00785a054. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

steganol
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Analytical method - additional description:

silica gel chromatography
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

steganol

Composition #13: WICKRAMARATNE, DBM., PENGSUPARP, T., MAR, W., CHAI, HB., CHAGWEDERA, TE., BEECHER, CWW., FARNSWORTH, NR., KINGHORN, AD., PEZZUTO, JM., CORDELL, GA. NOVEL ANTIMITOTIC DIBENZOCYCLO-OCTADIENE LIGNAN CONSTITUENTS OF THE STEM BARK OF STEGANOTAENIA-ARALIACEA . journal of natural products, 1993, vol. 56, no. 12, p. 2083–2090. DOI: 10.1021/np50102a009. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

steganangin, episteganangin, steganoate A, steganoate B, steganolide
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

steganangin, episteganangin, steganoate A, steganoate B, steganolide in stem bark

Composition #14: WICKRAMARATNE, DBM., PENGSUPARP, T., MAR, W., CHAI, HB., CHAGWEDERA, TE., BEECHER, CWW., FARNSWORTH, NR., KINGHORN, AD., PEZZUTO, JM., CORDELL, GA. NOVEL ANTIMITOTIC DIBENZOCYCLO-OCTADIENE LIGNAN CONSTITUENTS OF THE STEM BARK OF STEGANOTAENIA-ARALIACEA . journal of natural products, 1993, vol. 56, no. 12, p. 2083–2090. DOI: 10.1021/np50102a009. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

steganacin (RF-00004063-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

steganacin in stem bark