Draft - work in progress
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- Serenoa repens (W.Bartram) Small // Sabal serrulata (Michx.) Schult.f.
Serenoa repens (W.Bartram) Small // Sabal serrulata (Michx.) Schult.f.
- Family:
- Arecaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 1188
- Number of processed references:
- 2
Endpoint study
#1: Jacobsson, Ingela., Joensson, Anna K., Gerden, Barbro., Haegg, Staffan. Spontaneously reported adverse reactions in association with complementary and alternative medicine substances in Sweden. pharmacoepidemiology and drug safety, 2009, vol. 18, no. 11, p. 1039–1047. .
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Study relevance:
Human health
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Additional plant/substance description:
review of case reports of humans using as herbal medicine
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Type of toxicological test:
other (CHD008TT)
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Tested organism:
Human (as organism) (A056J)
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-
Route of exposure:
ORAL: UNSPECIFIED (OECD2234PL)
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Endpoint measured:
Dose not reported (CHD066EP)
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Target tissue:
cardiovascular / haematological: Blood Coagulation (TT010A)
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Effect description:
Decreased prothrombin, thrombocytopenia.
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Effect or parameter linked to the endpoint:
haematology (CHD023BE)
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Internal remarks:
Review noting case reports of adverse blood coagulation effects in humans
Endpoint study
#2: Jacobsson, Ingela., Joensson, Anna K., Gerden, Barbro., Haegg, Staffan. Spontaneously reported adverse reactions in association with complementary and alternative medicine substances in Sweden. pharmacoepidemiology and drug safety, 2009, vol. 18, no. 11, p. 1039–1047. .
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Study relevance:
Human health
-
Additional plant/substance description:
review of case reports of humans using as herbal medicine
-
Type of toxicological test:
other (CHD008TT)
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Tested organism:
Human (as organism) (A056J)
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Route of exposure:
ORAL: UNSPECIFIED (OECD2234PL)
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Endpoint measured:
Dose not reported (CHD066EP)
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Critical effect:
NEUROTOXICITY (TOX04A)
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Target tissue:
Neurologic (TT004A)
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Effect description:
Vertigo
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Effect or parameter linked to the endpoint:
neurology (CHD027BE)
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Internal remarks:
Review noting case reports of vertigo in humans
Endpoint study
#3: Ernst, E. The risk-benefit profile of commonly used herbal therapies: Ginkgo, St. John's wort, ginseng, echinacea, saw palmetto, and kava . annals of internal medicine, 2002, vol. 136, no. 1, p. 42–53. .
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Study relevance:
Human health
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Type of toxicological test:
other (CHD008TT)
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Tested organism:
Human (as organism) (A056J)
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Route of exposure:
ORAL: UNSPECIFIED (OECD2234PL)
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Endpoint measured:
Dose not reported (CHD066EP)
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Critical effect:
PULMONARY AND CARDIAC (TOX08A)
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Target tissue:
cardiovascular / haematological: Heart (TT011A)
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Effect description:
Hypertension
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Effect or parameter linked to the endpoint:
not reported (CHD030BE)
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Internal remarks:
Hypertension in humans (review)
