EFSA Compendium of Botanicals

Draft - work in progress

Ruscus hypoglossum L.

Family:: Asparagaceae
Approval state:: Approved
Number of articles retrieved:: 62
Number of processed references:: 2

Compositions

#1: total ruscogenin in rhizomes #2: total ruscogenin in herb #3: saponins in rhizomes

Endpoint Studies

Genotoxicity

Composition #1: Guvenc, A., Satir, E., Coskun, M. Determination of ruscogenin in Turkish Ruscus L. species by UPLC. chromatographia, 2007, vol. 66(Suppl.), p. S141–S145. .

Language:

English (en)
Plant part:

Roots and other underground parts used as staple food (as part-nature) (A0F5F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH + H2O (rhizomes)
Substance:

ruscogenin (RF-00004033-PAR)
Additional substance description:

total
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

TLC + UPLC
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.42
Internal remarks:

total ruscogenin in rhizomes

Composition #2: Guvenc, A., Satir, E., Coskun, M. Determination of ruscogenin in Turkish Ruscus L. species by UPLC. chromatographia, 2007, vol. 66(Suppl.), p. S141–S145. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH + H2O (herb)
Substance:

ruscogenin (RF-00004033-PAR)
Additional substance description:

total
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

TLC + UPLC
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.48
Internal remarks:

total ruscogenin in herb

Composition #3: de Combarieu, E., Falzoni, M., Fuzzati, N., Gattesco, F., Giori, A., Lovati, M., Pace, R. Identification of Ruscus steroidal saponins by HPLC-MS analysis. fitoterapia, 2002, vol. 73, no. 7-8, p. 583–596. DOI: 10.1016/S0367-326X(02)00220-4. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts used as staple food (as part-nature) (A0F5F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

EtOH (rhizomes)
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

HPLC-UV (F021A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

saponins in rhizomes