Draft - work in progress
-
- Sorrel (as plant) // Rumex acetosa L.
Sorrel (as plant) // Rumex acetosa L.
- Family:
- Polygonaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 1276
- Number of processed references:
- 6
Composition #1: Sharma, Mrs. Manju., Rangaswami, S. Chemical components of the roots of Rumex acetosa: isolation of ω-acetoxyaloe emodin, a new 1,8-dihydroxyanthraquinone derivative. indian journal of chemistry, section b: organic chemistry including medicinal chemistry, 1977, vol. 15B, no. 10, p. 884–5. .
-
-
Substance:
Emodin (RF-00003798-PAR)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
Composition #2: Sharma, Mrs. Manju., Rangaswami, S. Chemical components of the roots of Rumex acetosa: isolation of ω-acetoxyaloe emodin, a new 1,8-dihydroxyanthraquinone derivative. indian journal of chemistry, section b: organic chemistry including medicinal chemistry, 1977, vol. 15B, no. 10, p. 884–5. .
-
-
Substance:
chrysophanol (RF-00003737-PAR)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
Composition #3: Sharma, Mrs. Manju., Rangaswami, S. Chemical components of the roots of Rumex acetosa: isolation of ω-acetoxyaloe emodin, a new 1,8-dihydroxyanthraquinone derivative. indian journal of chemistry, section b: organic chemistry including medicinal chemistry, 1977, vol. 15B, no. 10, p. 884–5. .
-
-
Substance:
Aloe-emodin (RF-00003670-PAR)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
Composition #4: Hsiao, Pei-Ken., Ho, Li-I., Chen, Pi-Chu., Kuo, Hang-Chou. Botanical and chemical studies of Chinese herbal medicine "Yangti". yaoxue tongbao, 1980, vol. 15, no. 7, p. 48. .
-
-
Plant part:
Unspecified (A07XD)
-
Substance:
Nepodin (RF-00011305-PAR)
-
Analytical method code:
Unspecified (F598A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Nepodin in the plant (plant part unspecified)
Composition #5: Lee, NJ., Choi, JH., Koo, BS., Ryu, SY., Han, YH., Lee, SI., Lee, DU. Antimutagenicity and cytotoxicity of the constituents from the aerial parts of Rumex acetosa . biological & pharmaceutical bulletin, 2005, vol. 28, no. 11, p. 2158–2161. DOI: 10.1248/bpb.28.2158.
[
DOI link]
-
-
Plant part:
Aerial part of plants (as part-nature) (A166F)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
ethanol 80%
-
Substance:
anthraquinones (RF-00004343-PAR)
-
Additional substance description:
memodin-8-O-beta -D-glucopyranoside
-
Analytical method code:
Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
-
Analytical method - additional description:
silica gel chromatography
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
emodin-8-O-beta -D-glucopyranoside in aerial parts
Composition #6: Lee, NJ., Choi, JH., Koo, BS., Ryu, SY., Han, YH., Lee, SI., Lee, DU. Antimutagenicity and cytotoxicity of the constituents from the aerial parts of Rumex acetosa . biological & pharmaceutical bulletin, 2005, vol. 28, no. 11, p. 2158–2161. DOI: 10.1248/bpb.28.2158.
[
DOI link]
-
-
Plant part:
Aerial part of plants (as part-nature) (A166F)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
methanol 80%
-
Substance:
chrysophanol (RF-00003737-PAR)
-
Analytical method code:
Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
-
Analytical method - additional description:
silica gel chromatography
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
chrysophanol in aerial parts
Composition #7: Lee, NJ., Choi, JH., Koo, BS., Ryu, SY., Han, YH., Lee, SI., Lee, DU. Antimutagenicity and cytotoxicity of the constituents from the aerial parts of Rumex acetosa . biological & pharmaceutical bulletin, 2005, vol. 28, no. 11, p. 2158–2161. DOI: 10.1248/bpb.28.2158.
[
DOI link]
-
-
Plant part:
Aerial part of plants (as part-nature) (A166F)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
methanol 80%
-
Substance:
physcion (RF-00003993-PAR)
-
Analytical method code:
Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
-
Analytical method - additional description:
silica gel chromatography
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
physcion in aerial parts
Composition #8: Lee, NJ., Choi, JH., Koo, BS., Ryu, SY., Han, YH., Lee, SI., Lee, DU. Antimutagenicity and cytotoxicity of the constituents from the aerial parts of Rumex acetosa . biological & pharmaceutical bulletin, 2005, vol. 28, no. 11, p. 2158–2161. DOI: 10.1248/bpb.28.2158.
[
DOI link]
-
-
Plant part:
Aerial part of plants (as part-nature) (A166F)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
methanol 80%
-
Substance:
Emodin (RF-00003798-PAR)
-
Analytical method code:
Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
-
Analytical method - additional description:
silica gel chromatography
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
emodin in aerial parts
Composition #9: Wegiera, Magdalena., Smolarz, Helena D., Wianowska, Dorota., Dawidowicz, Andrzej L. Anthracene derivatives in some species of Rumex L. genus. acta societatis botanicorum poloniae, 2007, vol. 76, no. 2, p. 103–108. .
-
-
Plant part:
Live plants (as part-nature) (A0BA0)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
methanol 80%
-
Substance:
aloin A (RF-00003672-PAR)
-
Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
-
Analytical method - additional description:
RP-HPLC
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
aloin in fruits, leaves and roots
Composition #10: Wegiera, Magdalena., Smolarz, Helena D., Wianowska, Dorota., Dawidowicz, Andrzej L. Anthracene derivatives in some species of Rumex L. genus. acta societatis botanicorum poloniae, 2007, vol. 76, no. 2, p. 103–108. .
-
-
Plant part:
Fruit unspecified (as part-nature) (A067D)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
methanol 80%
-
Substance:
anthracene derivatives (RF-00004342-PAR)
-
Additional substance description:
aloe-emodin, aloin, chrysophanol, emodin, physcion, rhein,sennoside A, sennoside B
-
Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
-
Analytical method - additional description:
RP-HPLC
-
Result unit:
Milligram/gram (G060A)
-
Result expression:
Dry matter (B002A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
0.83
-
Internal remarks:
anthracene derivatives in fruits
Composition #11: Wegiera, Magdalena., Smolarz, Helena D., Wianowska, Dorota., Dawidowicz, Andrzej L. Anthracene derivatives in some species of Rumex L. genus. acta societatis botanicorum poloniae, 2007, vol. 76, no. 2, p. 103–108. .
-
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
methanol 80%
-
Substance:
anthracene derivatives (RF-00004342-PAR)
-
Additional substance description:
aloe-emodin, aloin, chrysophanol, emodin, physcion, rhein,sennoside A, sennoside B
-
Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
-
Analytical method - additional description:
RP-HPLC
-
Result unit:
Milligram/gram (G060A)
-
Result expression:
Dry matter (B002A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
1.59
-
Internal remarks:
anthracene derivatives in leaves
Composition #12: Wegiera, Magdalena., Smolarz, Helena D., Wianowska, Dorota., Dawidowicz, Andrzej L. Anthracene derivatives in some species of Rumex L. genus. acta societatis botanicorum poloniae, 2007, vol. 76, no. 2, p. 103–108. .
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
methanol 80%
-
Substance:
anthracene derivatives (RF-00004342-PAR)
-
Additional substance description:
aloe-emodin, aloin, chrysophanol, emodin, physcion, rhein,sennoside A, sennoside B
-
Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
-
Analytical method - additional description:
RP-HPLC
-
Result unit:
Milligram/gram (G060A)
-
Result expression:
Dry matter (B002A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
3.76
-
Internal remarks:
anthracene derivatives in roots
Composition #13: Wegiera, Magdalena., Smolarz, Helena D., Wianowska, Dorota., Dawidowicz, Andrzej L. Anthracene derivatives in some species of Rumex L. genus. acta societatis botanicorum poloniae, 2007, vol. 76, no. 2, p. 103–108. .
-
-
Plant part:
Live plants (as part-nature) (A0BA0)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
methanol 80%
-
Substance:
sennoside A (RF-00004051-PAR)
-
Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
-
Analytical method - additional description:
RP-HPLC
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
sennoside A in fruits, leaves and roots
Composition #14: Wegiera, Magdalena., Smolarz, Helena D., Wianowska, Dorota., Dawidowicz, Andrzej L. Anthracene derivatives in some species of Rumex L. genus. acta societatis botanicorum poloniae, 2007, vol. 76, no. 2, p. 103–108. .
-
-
Plant part:
Live plants (as part-nature) (A0BA0)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
methanol 80%
-
Substance:
chrysophanol (RF-00003737-PAR)
-
Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
-
Analytical method - additional description:
RP-HPLC
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
chrysophanol in fruits, leaves and roots
Composition #15: Wegiera, Magdalena., Smolarz, Helena D., Wianowska, Dorota., Dawidowicz, Andrzej L. Anthracene derivatives in some species of Rumex L. genus. acta societatis botanicorum poloniae, 2007, vol. 76, no. 2, p. 103–108. .
-
-
Plant part:
Live plants (as part-nature) (A0BA0)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
methanol 80%
-
Substance:
physcion (RF-00003993-PAR)
-
Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
-
Analytical method - additional description:
RP-HPLC
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
physcion in fruits, leaves and roots
Composition #16: Wegiera, Magdalena., Smolarz, Helena D., Wianowska, Dorota., Dawidowicz, Andrzej L. Anthracene derivatives in some species of Rumex L. genus. acta societatis botanicorum poloniae, 2007, vol. 76, no. 2, p. 103–108. .
-
-
Plant part:
Live plants (as part-nature) (A0BA0)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
methanol 80%
-
Substance:
rhein (RF-00004027-PAR)
-
Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
-
Analytical method - additional description:
RP-HPLC
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
rhein in leaves and roots
Composition #17: Wegiera, Magdalena., Smolarz, Helena D., Wianowska, Dorota., Dawidowicz, Andrzej L. Anthracene derivatives in some species of Rumex L. genus. acta societatis botanicorum poloniae, 2007, vol. 76, no. 2, p. 103–108. .
-
-
Plant part:
Live plants (as part-nature) (A0BA0)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
methanol 80%
-
Substance:
Aloe-emodin (RF-00003670-PAR)
-
Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
-
Analytical method - additional description:
RP-HPLC
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
aloe-emodin in fruits, leaves and roots
Composition #18: Wegiera, Magdalena., Smolarz, Helena D., Wianowska, Dorota., Dawidowicz, Andrzej L. Anthracene derivatives in some species of Rumex L. genus. acta societatis botanicorum poloniae, 2007, vol. 76, no. 2, p. 103–108. .
-
-
Plant part:
Live plants (as part-nature) (A0BA0)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
methanol 80%
-
Substance:
Emodin (RF-00003798-PAR)
-
Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
-
Analytical method - additional description:
RP-HPLC
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
emodin in fruits, leaves and roots
Composition #19: Wegiera, Magdalena., Smolarz, Helena D., Wianowska, Dorota., Dawidowicz, Andrzej L. Anthracene derivatives in some species of Rumex L. genus. acta societatis botanicorum poloniae, 2007, vol. 76, no. 2, p. 103–108. .
-
-
Plant part:
Live plants (as part-nature) (A0BA0)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
methanol 80%
-
Substance:
sennoside B (RF-00004052-PAR)
-
Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
-
Analytical method - additional description:
RP-HPLC
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
sennoside B in fruits, leaves and roots
Composition #20: Mithril, Charlotte., Dragsted, Lars Ove. Safety evaluation of some wild plants in the New Nordic Diet. food and chemical toxicology, 2012, vol. 50, no. 12, p. 4461–4467. DOI: 10.1016/j.fct.2012.09.016.
[
DOI link]
-
-
Plant part:
Unspecified (A07XD)
-
Additional extraction description:
unspecified
-
Substance:
oxalic acid (RF-00000356-NTR)
-
Analytical method - additional description:
unspecified
-
-
Result expression:
Whole weight (B001A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
3000
-
Internal remarks:
oxalic acids in leaves
Endpoint study
#1: Suckling, C.W. The recent case of poisoning by common sorrel (rumex acetosa). british medical journal, 1886, vol. 2, no. 1339, p. 436. DOI: 10.1136/bmj.2.1339.436.
[
DOI link]
-
Study relevance:
Human health
-
Plant part:
Stem / stalk (as part-nature) (A067S)
-
Type of toxicological test:
case report (CHD060TT)
-
Limit test:
Not applicable
-
Tested organism:
Human (as organism) (A056J)
-
-
Route of exposure:
ORAL: UNSPECIFIED (OECD2234PL)
-
Unit of exposure duration:
single (food/feed) (G203A)
-
Number of organisms dosed:
1
-
-
Endpoint measured:
Dose not reported (CHD066EP)
-
Critical effect:
SYSTEMIC (TOX01A)
-
Target tissue:
Neurologic (TT004A)
-
Effect description:
unconsciousness, face cold and pale, forehead wet, limbs cold, breathing slow, frequent and death
-
Effect or parameter linked to the endpoint:
mortality (CHD010BE)
-
Internal remarks:
case report - mortality, unconsciousness