EFSA
ecomole
vscht
  2. Rosemary (as plant) // Rosmarinus officinalis L.

Rosemary (as plant) // Rosmarinus officinalis L.

Family:
Lamiaceae
Approval state:
Approved
Number of articles retrieved:
8120
Number of processed references:
7
Compositions
#1: 1,8-cineole in essential oil #2: Camphor in essential oil #3: Piperitone in essential oil #4: Myrcene in essential oil #5: Rosmanol (a diterpene) in supercritical extract of leaves #6: Methyl Carnosate (a diterpene) in supercritical extract of leaves #7: Rosmanol Isomer (a diterpene) in supercritical extract of leaves #8: Carnosol (a phenolic diterpene) in supercritical extract #9: Carnosic acid (a phenolic diterpene) in supercritical extract #10: Verbenone in essential oil of leaves #11: 1,8-cineole in essential oil of aerial parts #12: Camphor in essential oil of aerial parts #13: Myrcene in essential oil of aerial parts
Endpoint Studies
#1: Gastrointestinal hemorrhage at high doses (no details - review) #2: Hepatic disease at high doses (no details - review) #3: Kidney disease at high doses (no details - review) #4: Epilepsy at high doses (no details - review) #5: One case of human poisoning in Morocco (no details - review)
Genotoxicity
#1: Genotoxicity in mice (in vivo comet assay) #2: Mutagenicity in mice (erythrocyte micronucleus test) #3: Mutagenicity in rats (erythrocyte micronucleus test) #4: Genotoxicity in rats (chromosome abberrations) #5: Genotoxicity of essential oil in human peripheral lymphocytes in vitro
Composition #1: Dimitrijevic, Suzana I., Mihajlovski, Katarina R., Antonovic, Dusan G., Milanovic-Stevanovic, Mirjana R., Mijin, Dusan Z. A study of the synergistic antilisterial effects of a sub-lethal dose of lactic acid and essential oils from Thymus vulgaris L., Rosmarinus officinalis L. and Origanum vulgare L.. food chemistry, 2007, vol. 104, no. 2, p. 774–782. DOI: 10.1016/j.foodchem.2006.12.028. [DOI link]
Composition #2: Dimitrijevic, Suzana I., Mihajlovski, Katarina R., Antonovic, Dusan G., Milanovic-Stevanovic, Mirjana R., Mijin, Dusan Z. A study of the synergistic antilisterial effects of a sub-lethal dose of lactic acid and essential oils from Thymus vulgaris L., Rosmarinus officinalis L. and Origanum vulgare L.. food chemistry, 2007, vol. 104, no. 2, p. 774–782. DOI: 10.1016/j.foodchem.2006.12.028. [DOI link]
Composition #3: Dimitrijevic, Suzana I., Mihajlovski, Katarina R., Antonovic, Dusan G., Milanovic-Stevanovic, Mirjana R., Mijin, Dusan Z. A study of the synergistic antilisterial effects of a sub-lethal dose of lactic acid and essential oils from Thymus vulgaris L., Rosmarinus officinalis L. and Origanum vulgare L.. food chemistry, 2007, vol. 104, no. 2, p. 774–782. DOI: 10.1016/j.foodchem.2006.12.028. [DOI link]
Composition #4: Dimitrijevic, Suzana I., Mihajlovski, Katarina R., Antonovic, Dusan G., Milanovic-Stevanovic, Mirjana R., Mijin, Dusan Z. A study of the synergistic antilisterial effects of a sub-lethal dose of lactic acid and essential oils from Thymus vulgaris L., Rosmarinus officinalis L. and Origanum vulgare L.. food chemistry, 2007, vol. 104, no. 2, p. 774–782. DOI: 10.1016/j.foodchem.2006.12.028. [DOI link]
Composition #5: Anadon, Arturo., Martinez-Larranaga, Maria R., Martinez, Maria A., Ares, Irma., Garcia-Risco, Monica R., Senorans, Francisco J., Reglero, Guillermo. Acute oral safety study of rosemary extracts in rats. journal of food protection, 2008, vol. 71, no. 4, p. 790–795. DOI: 10.4315/0362-028X-71.4.790. [DOI link]
Composition #6: Anadon, Arturo., Martinez-Larranaga, Maria R., Martinez, Maria A., Ares, Irma., Garcia-Risco, Monica R., Senorans, Francisco J., Reglero, Guillermo. Acute oral safety study of rosemary extracts in rats. journal of food protection, 2008, vol. 71, no. 4, p. 790–795. DOI: 10.4315/0362-028X-71.4.790. [DOI link]
Composition #7: Anadon, Arturo., Martinez-Larranaga, Maria R., Martinez, Maria A., Ares, Irma., Garcia-Risco, Monica R., Senorans, Francisco J., Reglero, Guillermo. Acute oral safety study of rosemary extracts in rats. journal of food protection, 2008, vol. 71, no. 4, p. 790–795. DOI: 10.4315/0362-028X-71.4.790. [DOI link]
Composition #8: Anadon, Arturo., Martinez, Maria A., Ares, Irma., Castellano, Victor., Martinez-Larranaga, Maria R., Corzo, Nieves., Olano, Agustin., Montilla, Antonia., Recio, Isidra., Martinez-Maqueda, Daniel., Miralles, Beatriz., Fornari, Tiziana., Garcia-Risco, Monica R., Gonzalez, Monserrat., Reglero, Guillermo. Acute and Repeated Dose (28 Days) Oral Safety Studies of ALIBIRD in Rats. journal of food protection, 2013, vol. 76, no. 7, p. 1226–1239. DOI: 10.4315/0362-028X.JFP-13-032. [DOI link]
Composition #9: Anadon, Arturo., Martinez, Maria A., Ares, Irma., Castellano, Victor., Martinez-Larranaga, Maria R., Corzo, Nieves., Olano, Agustin., Montilla, Antonia., Recio, Isidra., Martinez-Maqueda, Daniel., Miralles, Beatriz., Fornari, Tiziana., Garcia-Risco, Monica R., Gonzalez, Monserrat., Reglero, Guillermo. Acute and Repeated Dose (28 Days) Oral Safety Studies of ALIBIRD in Rats. journal of food protection, 2013, vol. 76, no. 7, p. 1226–1239. DOI: 10.4315/0362-028X.JFP-13-032. [DOI link]
Composition #10: Gudek, Melek., Cetin, Huseyin. Fumigant Toxicity on Adults of Callosobruchus maculatus (F.) (Coleoptera: Chrysomelidae) of Essential Oil from Rosmarinus officinalis L. and its Side Effects on Chickpea Grains. journal of essential oil bearing plants, 2017, vol. 20, no. 1, p. 272–281. .
Composition #11: Contini, Adele., Di Bello, Domenica., Azzara, Alessia., Giovanelli, Silvia., D'Urso, Giuseppina., Piaggi, Simona., Pinto, Barbara., Pistelli, Luisa., Scarpato, Roberto., Testi, Serena. Assessing the cytotoxic/genotoxic activity and estrogenic/antiestrogenic potential of essential oils from seven aromatic plants. food and chemical toxicology, 2020, vol. 138 . DOI: 10.1016/j.fct.2020.111205. [DOI link]
Composition #12: Contini, Adele., Di Bello, Domenica., Azzara, Alessia., Giovanelli, Silvia., D'Urso, Giuseppina., Piaggi, Simona., Pinto, Barbara., Pistelli, Luisa., Scarpato, Roberto., Testi, Serena. Assessing the cytotoxic/genotoxic activity and estrogenic/antiestrogenic potential of essential oils from seven aromatic plants. food and chemical toxicology, 2020, vol. 138 . DOI: 10.1016/j.fct.2020.111205. [DOI link]
Composition #13: Contini, Adele., Di Bello, Domenica., Azzara, Alessia., Giovanelli, Silvia., D'Urso, Giuseppina., Piaggi, Simona., Pinto, Barbara., Pistelli, Luisa., Scarpato, Roberto., Testi, Serena. Assessing the cytotoxic/genotoxic activity and estrogenic/antiestrogenic potential of essential oils from seven aromatic plants. food and chemical toxicology, 2020, vol. 138 . DOI: 10.1016/j.fct.2020.111205. [DOI link]
Endpoint study #1: Loutfia, Toilabiya., Hinde, Hami., Abdelmajid, Soulaymani., Naima, Rhalem., Laheen, Ouammi., Doha, Benali., Adbelrhani, Mokhtari., Rachida, Soulaymani-Bencheikh. Poisoning by plants in the Taza-Al Hoceima-Taounate region in Morocco. pakistan journal of scientific and industrial research, series b: biological sciences, 2013, vol. 56, no. 1, p. 23–28. .
Endpoint study #2: Loutfia, Toilabiya., Hinde, Hami., Abdelmajid, Soulaymani., Naima, Rhalem., Laheen, Ouammi., Doha, Benali., Adbelrhani, Mokhtari., Rachida, Soulaymani-Bencheikh. Poisoning by plants in the Taza-Al Hoceima-Taounate region in Morocco. pakistan journal of scientific and industrial research, series b: biological sciences, 2013, vol. 56, no. 1, p. 23–28. .
Endpoint study #3: Loutfia, Toilabiya., Hinde, Hami., Abdelmajid, Soulaymani., Naima, Rhalem., Laheen, Ouammi., Doha, Benali., Adbelrhani, Mokhtari., Rachida, Soulaymani-Bencheikh. Poisoning by plants in the Taza-Al Hoceima-Taounate region in Morocco. pakistan journal of scientific and industrial research, series b: biological sciences, 2013, vol. 56, no. 1, p. 23–28. .
Endpoint study #4: Loutfia, Toilabiya., Hinde, Hami., Abdelmajid, Soulaymani., Naima, Rhalem., Laheen, Ouammi., Doha, Benali., Adbelrhani, Mokhtari., Rachida, Soulaymani-Bencheikh. Poisoning by plants in the Taza-Al Hoceima-Taounate region in Morocco. pakistan journal of scientific and industrial research, series b: biological sciences, 2013, vol. 56, no. 1, p. 23–28. .
Endpoint study #5: Loutfia, Toilabiya., Hinde, Hami., Abdelmajid, Soulaymani., Naima, Rhalem., Laheen, Ouammi., Doha, Benali., Adbelrhani, Mokhtari., Rachida, Soulaymani-Bencheikh. Poisoning by plants in the Taza-Al Hoceima-Taounate region in Morocco. pakistan journal of scientific and industrial research, series b: biological sciences, 2013, vol. 56, no. 1, p. 23–28. .
Genotox #1: Maistro, E. L., Mota, S. F., Lima, E. B., Bernardes, B. M., Goulart, F. C. Genotoxicity and mutagenicity of Rosmarinus officinalis (Labiatae) essential oil in mammalian cells in vivo. genetics and molecular research, 2010, vol. 9, no. 4, p. 2113–2122. DOI: 10.4238/vol9-4gmr857. [DOI link]
Genotox #2: Maistro, E. L., Mota, S. F., Lima, E. B., Bernardes, B. M., Goulart, F. C. Genotoxicity and mutagenicity of Rosmarinus officinalis (Labiatae) essential oil in mammalian cells in vivo. genetics and molecular research, 2010, vol. 9, no. 4, p. 2113–2122. DOI: 10.4238/vol9-4gmr857. [DOI link]
Genotox #3: Maistro, E. L., Mota, S. F., Lima, E. B., Bernardes, B. M., Goulart, F. C. Genotoxicity and mutagenicity of Rosmarinus officinalis (Labiatae) essential oil in mammalian cells in vivo. genetics and molecular research, 2010, vol. 9, no. 4, p. 2113–2122. DOI: 10.4238/vol9-4gmr857. [DOI link]
Genotox #4: Maistro, E. L., Mota, S. F., Lima, E. B., Bernardes, B. M., Goulart, F. C. Genotoxicity and mutagenicity of Rosmarinus officinalis (Labiatae) essential oil in mammalian cells in vivo. genetics and molecular research, 2010, vol. 9, no. 4, p. 2113–2122. DOI: 10.4238/vol9-4gmr857. [DOI link]
Genotox #5: Contini, Adele., Di Bello, Domenica., Azzara, Alessia., Giovanelli, Silvia., D'Urso, Giuseppina., Piaggi, Simona., Pinto, Barbara., Pistelli, Luisa., Scarpato, Roberto., Testi, Serena. Assessing the cytotoxic/genotoxic activity and estrogenic/antiestrogenic potential of essential oils from seven aromatic plants. food and chemical toxicology, 2020, vol. 138 . DOI: 10.1016/j.fct.2020.111205. [DOI link]