EFSA Compendium of Botanicals

Draft - work in progress

Rosa gallica L.

Family:: Rosaceae
Approval state:: Approved
Number of articles retrieved:: 168
Number of processed references:: 2

Compositions

#1: Ellagitannins (hydrolysable tannins) in flowers #2: gallicoside A, B, C in flowers

Endpoint Studies

#1: inhibitory effects of 50% ethanol extracts against a-amylase and a-glucosidase

Genotoxicity

Composition #1: Ochir, Sarangowa., Nishizawa, Makoto., Park, Byoung Jae., Ishii, Kouta., Kanazawa, Tsutomu., Funaki, Minoru., Yamagishi, Takashi. Inhibitory effects of Rosa gallica on the digestive enzymes. journal of natural medicines, 2010, vol. 64, no. 3, p. 275–280. DOI: 10.1007/s11418-010-0402-0. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

50% aqueous ethanol extracts
Substance:

Ellagitannins (hydrolysable tannins) Ellagitannins (hydrolysable tannins) (RF-00004379-PAR)
Additional substance description:

tellimagrandin I, tellimagrandin II, rugosin A rugosin D, casuarictin, strictinin, isostrictinin, valoneoic acid
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Ellagitannins (hydrolysable tannins) in flowers

Composition #2: BUGORSKY, PS., MELNIKOV, VN. TRITERPENE AND STEROIDAL GLYCOSIDES ROSA-GALLICA. khimiya prirodnykh soedinenii, 1977, no. 3, p. 420–421. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol
Substance:

steroidal glycosides (RF-00011482-PAR)
Additional substance description:

gallicoside A, B, C
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

silica gel chromatography
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

gallicoside A, B, C in flowers

Endpoint study #1: Ochir, Sarangowa., Nishizawa, Makoto., Park, Byoung Jae., Ishii, Kouta., Kanazawa, Tsutomu., Funaki, Minoru., Yamagishi, Takashi. Inhibitory effects of Rosa gallica on the digestive enzymes. journal of natural medicines, 2010, vol. 64, no. 3, p. 275–280. DOI: 10.1007/s11418-010-0402-0. [DOI link]

Study relevance:

Human health
Plant part:

Flower (as part-nature) (A067B)
Preparation/Extraction method:

Solvent extraction (A0BZR)
Additional plant/substance description:

ethanol
Type of toxicological test:

in vitro (CHD061TT)
Endpoint measured:

Enzyme inhibition (CHD067EP)
Concentration unit:

Percent (G138A)
Effect concentration:

50
Critical effect:

Digestive (TOX18A)
Target tissue:

Digestive (TT002A)
Effect description:

inhibition of alpha amylase activity and alpha glucosidase
Effect or parameter linked to the endpoint:

enzyme inhibition (CHD032BE)
Internal remarks:

inhibitory effects of 50% ethanol extracts against a-amylase and a-glucosidase