EFSA Compendium of Botanicals

Draft - work in progress

Ranunculus sceleratus L.

Family:: Ranunculaceae
Approval state:: Approved
Number of articles retrieved:: 263
Number of processed references:: 4

Endpoint Studies

Genotoxicity

Composition #1: Mahran, Gamal H., El-Alfy, T. S., Saber, A. Hifny. New simple method for the determination of protoanemonin in Ranunculus sceleratus. bulletin of the faculty of pharmacy (cairo university), 1969, vol. 1968, 7, no. 1, p. 135–41. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

steam distillation
Substance:

ranunculin (RF-00011193-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Protoanemonin

Composition #2: Mahran, Gamal H., El-Alfy, T. S., Saber, A. Hifny. New simple method for the determination of protoanemonin in Ranunculus sceleratus. bulletin of the faculty of pharmacy (cairo university), 1969, vol. 1968, 7, no. 1, p. 135–41. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

steam distillation
Substance:

anemonin (RF-00011185-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Anemonin

Composition #3: Mahran, Gamal H., El-Alfy, T. S., Saber, A. Hifny. New simple method for the determination of protoanemonin in Ranunculus sceleratus. bulletin of the faculty of pharmacy (cairo university), 1969, vol. 1968, 7, no. 1, p. 135–41. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

steam distillation
Substance:

Protoanemonin (RF-00003593-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Protoanemonin

Composition #4: Gao Xiao-zhong., Zhou Chang-xin., Zhang Shui-li., Yao Wei., Zhao Yu. Studies on the chemical constituents in herb of Ranunculus sceleratus. zhongguo zhongyao zazhi, 2005, vol. 30, no. 2, p. 124–126. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

3,4-Dihydroxybenzoic acid (RF-00008853-PAR)
Additional substance description:

protocatechuic acid
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

EI-MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Protocatechuic acid

Composition #5: Gao Xiao-zhong., Zhou Chang-xin., Zhang Shui-li., Yao Wei., Zhao Yu. Studies on the chemical constituents in herb of Ranunculus sceleratus. zhongguo zhongyao zazhi, 2005, vol. 30, no. 2, p. 124–126. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

Isoscopoletin (RF-00010985-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

EI-MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Isoscopoletin

Composition #6: Gao Xiao-zhong., Zhou Chang-xin., Zhang Shui-li., Yao Wei., Zhao Yu. Studies on the chemical constituents in herb of Ranunculus sceleratus. zhongguo zhongyao zazhi, 2005, vol. 30, no. 2, p. 124–126. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

scoparone (RF-00004047-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

EI-MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Scoparone

Composition #7: Gao Xiao-zhong., Zhou Chang-xin., Zhang Shui-li., Yao Wei., Zhao Yu. Studies on the chemical constituents in herb of Ranunculus sceleratus. zhongguo zhongyao zazhi, 2005, vol. 30, no. 2, p. 124–126. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

3,4-Dihydroxybenzaldehyde (RF-00001977-PAR)
Additional substance description:

protocatechuic aldehyde
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

EI-MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Protocatechuic aldehyde

Composition #8: BHARGAVA, KP., KISHOR, K., PANT, MC., SAXENA, PR. IDENTIFICATION OF TRYPTAMINE DERIVATIVES IN RANUNCULUS SCELERATUS L. british journal of pharmacology and chemotherapy, 1965, vol. 25, no. 3, p. 743–&. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetone
Substance:

Tryptamine (RF-00000009-BGA)
Additional substance description:

tryptamine derivatives
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

tryptamine derivatives in leaves and stems

Composition #9: MAHRAN, GH., SABER, AH., ELALFY, T. SPECTROPHOTOMETRIC DETERMINATION OF PROTOANEMONIN ANEMONIN AND RANUNCULIN IN RANUNCULUS SCELERATUS L . planta medica, 1968, vol. 16, no. 3, p. 323–&. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Additional extraction description:

distillation
Substance:

Protoanemonin (RF-00003593-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.241-0.249
Internal remarks:

protoanemonin in leaves

Composition #10: MAHRAN, GH., SABER, AH., ELALFY, T. SPECTROPHOTOMETRIC DETERMINATION OF PROTOANEMONIN ANEMONIN AND RANUNCULIN IN RANUNCULUS SCELERATUS L . planta medica, 1968, vol. 16, no. 3, p. 323–&. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Additional extraction description:

distillation
Substance:

Protoanemonin (RF-00003593-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.291-0.295
Internal remarks:

protoanemonin in roots

Composition #11: MAHRAN, GH., SABER, AH., ELALFY, T. SPECTROPHOTOMETRIC DETERMINATION OF PROTOANEMONIN ANEMONIN AND RANUNCULIN IN RANUNCULUS SCELERATUS L . planta medica, 1968, vol. 16, no. 3, p. 323–&. .

Language:

English (en)
Plant part:

Fruit peel (as part-nature) (A067G)
Additional extraction description:

distillation
Substance:

ranunculin (RF-00011193-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.739-0.742
Internal remarks:

ranunculin in fruits

Composition #12: MAHRAN, GH., SABER, AH., ELALFY, T. SPECTROPHOTOMETRIC DETERMINATION OF PROTOANEMONIN ANEMONIN AND RANUNCULIN IN RANUNCULUS SCELERATUS L . planta medica, 1968, vol. 16, no. 3, p. 323–&. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Additional extraction description:

distillation
Substance:

anemonin (RF-00011185-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.051-0.059
Internal remarks:

anemonin in herb

Composition #13: MAHRAN, GH., SABER, AH., ELALFY, T. SPECTROPHOTOMETRIC DETERMINATION OF PROTOANEMONIN ANEMONIN AND RANUNCULIN IN RANUNCULUS SCELERATUS L . planta medica, 1968, vol. 16, no. 3, p. 323–&. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Additional extraction description:

distillation
Substance:

Protoanemonin (RF-00003593-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.237-0.239
Internal remarks:

protoanemonin in stem

Composition #14: MAHRAN, GH., SABER, AH., ELALFY, T. SPECTROPHOTOMETRIC DETERMINATION OF PROTOANEMONIN ANEMONIN AND RANUNCULIN IN RANUNCULUS SCELERATUS L . planta medica, 1968, vol. 16, no. 3, p. 323–&. .

Language:

English (en)
Plant part:

Fruit peel (as part-nature) (A067G)
Additional extraction description:

distillation
Substance:

Protoanemonin (RF-00003593-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.273-0.277
Internal remarks:

protoanemonin in fruits

Composition #15: MAHRAN, GH., SABER, AH., ELALFY, T. SPECTROPHOTOMETRIC DETERMINATION OF PROTOANEMONIN ANEMONIN AND RANUNCULIN IN RANUNCULUS SCELERATUS L . planta medica, 1968, vol. 16, no. 3, p. 323–&. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Additional extraction description:

distillation
Substance:

Protoanemonin (RF-00003593-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.250-0.253
Internal remarks:

protoanemonin in herb

Composition #16: MAHRAN, GH., SABER, AH., ELALFY, T. SPECTROPHOTOMETRIC DETERMINATION OF PROTOANEMONIN ANEMONIN AND RANUNCULIN IN RANUNCULUS SCELERATUS L . planta medica, 1968, vol. 16, no. 3, p. 323–&. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Additional extraction description:

distillation
Substance:

ranunculin (RF-00011193-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.648-0.662
Internal remarks:

ranunculin in leaves

Composition #17: MAHRAN, GH., SABER, AH., ELALFY, T. SPECTROPHOTOMETRIC DETERMINATION OF PROTOANEMONIN ANEMONIN AND RANUNCULIN IN RANUNCULUS SCELERATUS L . planta medica, 1968, vol. 16, no. 3, p. 323–&. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Additional extraction description:

distillation
Substance:

anemonin (RF-00011185-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.044-0.049
Internal remarks:

anemonin in stem

Composition #18: MAHRAN, GH., SABER, AH., ELALFY, T. SPECTROPHOTOMETRIC DETERMINATION OF PROTOANEMONIN ANEMONIN AND RANUNCULIN IN RANUNCULUS SCELERATUS L . planta medica, 1968, vol. 16, no. 3, p. 323–&. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Additional extraction description:

distillation
Substance:

ranunculin (RF-00011193-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.785-0.790
Internal remarks:

ranunculin in roots

Composition #19: MAHRAN, GH., SABER, AH., ELALFY, T. SPECTROPHOTOMETRIC DETERMINATION OF PROTOANEMONIN ANEMONIN AND RANUNCULIN IN RANUNCULUS SCELERATUS L . planta medica, 1968, vol. 16, no. 3, p. 323–&. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Additional extraction description:

distillation
Substance:

anemonin (RF-00011185-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.053-0.055
Internal remarks:

anemonin in roots

Composition #20: MAHRAN, GH., SABER, AH., ELALFY, T. SPECTROPHOTOMETRIC DETERMINATION OF PROTOANEMONIN ANEMONIN AND RANUNCULIN IN RANUNCULUS SCELERATUS L . planta medica, 1968, vol. 16, no. 3, p. 323–&. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Additional extraction description:

distillation
Substance:

ranunculin (RF-00011193-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.642-0.648
Internal remarks:

ranunculin in stem

Composition #21: MAHRAN, GH., SABER, AH., ELALFY, T. SPECTROPHOTOMETRIC DETERMINATION OF PROTOANEMONIN ANEMONIN AND RANUNCULIN IN RANUNCULUS SCELERATUS L . planta medica, 1968, vol. 16, no. 3, p. 323–&. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Additional extraction description:

distillation
Substance:

anemonin (RF-00011185-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.040-0.049
Internal remarks:

anemonin in leaves

Composition #22: MAHRAN, GH., SABER, AH., ELALFY, T. SPECTROPHOTOMETRIC DETERMINATION OF PROTOANEMONIN ANEMONIN AND RANUNCULIN IN RANUNCULUS SCELERATUS L . planta medica, 1968, vol. 16, no. 3, p. 323–&. .

Language:

English (en)
Plant part:

Fruit peel (as part-nature) (A067G)
Additional extraction description:

distillation
Substance:

anemonin (RF-00011185-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.050-0.055
Internal remarks:

anemonin in fruits

Composition #23: MAHRAN, GH., SABER, AH., ELALFY, T. SPECTROPHOTOMETRIC DETERMINATION OF PROTOANEMONIN ANEMONIN AND RANUNCULIN IN RANUNCULUS SCELERATUS L . planta medica, 1968, vol. 16, no. 3, p. 323–&. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Additional extraction description:

distillation
Substance:

ranunculin (RF-00011193-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.671-0.679
Internal remarks:

ranunculin in herb