EFSA Compendium of Botanicals

Draft - work in progress

Ptelea trifoliata L.

Family:: Rutaceae
Approval state:: Approved
Number of articles retrieved:: 155
Number of processed references:: 7

Compositions

#1: (-)-marmesin in leaves #2: isopimpinellin in leaves #3: phellopterin in leaves #4: Quinoline alkaloid (3-isopentenyl4-methoxy-7,8-methylenedioxy-2-quinolone) in leaves #5: furoquinoline alkaloids in leaves ( lsoptelefolonium, Ptelefolidonium, Hydroxyluninium) #6: myrcene in leaves #7: myrcene in bark #8: kokusaginine in roots #9: Furoquinoline alkaloids (ptelefolonium and isoptelefolonium) in leaves and fruits #10: Alkaloids (ptelefolonium, isoptelefolonium, hydroxyluninium, ptelefolidonium) in leaves

Endpoint Studies

Genotoxicity

Composition #1: Dreyer, David L. Chemotaxonomy of the Rutaceae. V. Coumarins and alkaloids of the genus Ptelea. phytochemistry (elsevier), 1969, vol. 8, no. 6, p. 1013–20. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetone
Substance:

marmesin (RF-00003917-PAR)
Additional substance description:

(-)-marmesin
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

(-)-marmesin in leaves

Composition #2: Dreyer, David L. Chemotaxonomy of the Rutaceae. V. Coumarins and alkaloids of the genus Ptelea. phytochemistry (elsevier), 1969, vol. 8, no. 6, p. 1013–20. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetone
Substance:

Isopimpinellin (RF-00003784-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

isopimpinellin in leaves

Composition #3: Dreyer, David L. Chemotaxonomy of the Rutaceae. V. Coumarins and alkaloids of the genus Ptelea. phytochemistry (elsevier), 1969, vol. 8, no. 6, p. 1013–20. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetone
Substance:

Phellopterin (RF-00003560-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

phellopterin in leaves

Composition #4: Dreyer, David L. Chemotaxonomy of the Rutaceae. V. Coumarins and alkaloids of the genus Ptelea. phytochemistry (elsevier), 1969, vol. 8, no. 6, p. 1013–20. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetone
Substance:

Quinoline alkaloids (RF-00004326-PAR)
Additional substance description:

3-isopentenyl-4-methoxy-7,8-methylenedioxy-2-quinolone
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Quinoline alkaloid (3-isopentenyl4-methoxy-7,8-methylenedioxy-2-quinolone) in leaves

Composition #5: Pothier, Jacques., Petit-Paly, Genevieve., Montagu, Monique., Galand, Nicole., Chenieux, Jean Claude., Rideau, Marc., Viel, Claude. Separation of quinolizidine and dihydrofuro 2,3-b quinolinium alkaloids by overpressured layer chromatography (OPLC). journal of planar chromatography--modern tlc, 1990, vol. 3(July-Aug.), p. 356–8. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

furoquinoline alkaloids (RF-00004382-PAR)
Additional substance description:

lsoptelefolonium, Ptelefolidonium, Hydroxyluninium
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

furoquinoline alkaloids in leaves ( lsoptelefolonium, Ptelefolidonium, Hydroxyluninium)

Composition #6: Takaku, Sayaka., Setzer, William N. Chemical composition of the leaf essential oil of Ptelea trifoliata. journal of essential oil bearing plants, 2007, vol. 10, no. 2, p. 104–108. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

8.7-18.7
Internal remarks:

myrcene in leaves

Composition #7: Steinberg, Kelly Marie., Satyal, Prabodh., Setzer, William N. Bark Essential Oils of Zanthoxylum clava-herculis and Ptelea trifoliata: Enantiomeric Distribution of Monoterpenoids . natural product communications, 2017, vol. 12, no. 6, p. 961–963. .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.9
Internal remarks:

myrcene in bark

Composition #8: MULVEY, RK., ZALEWSKI, CJ. KOKUSAGININE - PLANT SOURCES AND ITS ISOLATION FROM PTELEA TRIFOLIATA ROOT BARK . economic botany, 1969, vol. 23, no. 1, p. 75–&. DOI: 10.1007/BF02862974. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

petroleum ether
Substance:

kokusaginine (RF-00003890-PAR)
Analytical method code:

Chromatographic tests (F015A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.015
Internal remarks:

kokusaginine in roots

Composition #9: RIDEAU, M., VERCHERE, C., HIBON, P., CHENIEUX, JC., MAUPAS, P., VIEL, C. DIHYDROFUROQUINOLINE ALKALOIDS FROM RUTACEAE - ISOLATION, STRUCTURE, BIOLOGICAL PROPERTIES . phytochemistry, 1979, vol. 18, no. 1, p. 155–159. DOI: 10.1016/S0031-9422(00)90936-1. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH (leaves and fruits)
Substance:

furoquinoline alkaloids (RF-00004382-PAR)
Additional substance description:

ptelefolonium and isoptelefolonium
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Furoquinoline alkaloids (ptelefolonium and isoptelefolonium) in leaves and fruits

Composition #10: PETITPALY, G., MONTAGU, M., MERIENNE, C., AMBROSE, JD., RIDEAU, M., VIEL, C., CHENIEUX, JC. NEW ALKALOIDS FROM PTELEA-TRIFOLIATA. planta medica, 1989, no. 2, p. 209–210. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

ptelefolonium, isoptelefolonium, hydroxyluninium, ptelefolidonium
Analytical method code:

Element spectroscopy (F051A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids (ptelefolonium, isoptelefolonium, hydroxyluninium, ptelefolidonium) in leaves