EFSA Compendium of Botanicals

Draft - work in progress

Psychotria viridis Ruiz & Pav.

Family:: Rubiaceae
Approval state:: Approved
Number of articles retrieved:: 113
Number of processed references:: 2

Compositions

#1: 2-methyl-1,2,3,4-tetrahydro-beta-carboline #2: Dimethyltryptamine and N-monomethyltryptamine in leaves #3: N,N-dimethyltryptamine in leaves

Endpoint Studies

Genotoxicity

Composition #1: Rivier, L., Lindgren, J.-E. "Ayahuasca," the South American hallucinogenic drink: An ethnobotanical and chemical investigation. economic botany, 1972, vol. 26, no. 2, p. 101–129. DOI: 10.1007/BF02860772. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Methanol
Substance:

carboline alkaloids (RF-00004384-PAR)
Additional substance description:

2-methyl-1,2,3,4-tetrahydro-beta-carboline
Analytical method code:

Gaschromatography (GC) (F037A)
Analytical method - additional description:

GC, GC-MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

2-methyl-1,2,3,4-tetrahydro-beta-carboline

Composition #2: Rivier, L., Lindgren, J.-E. "Ayahuasca," the South American hallucinogenic drink: An ethnobotanical and chemical investigation. economic botany, 1972, vol. 26, no. 2, p. 101–129. DOI: 10.1007/BF02860772. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Methanol
Substance:

tryptamine alkaloids (RF-00004388-PAR)
Additional substance description:

N-monomethyltryptamine and Dimethyltryptamine
Analytical method code:

Gaschromatography (GC) (F037A)
Analytical method - additional description:

GC, GC-MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Dimethyltryptamine and N-monomethyltryptamine in leaves

Composition #3: Soares, Debora B. S., Duarte, Lucienir P., Cavalcanti, Andre D., Silva, Fernando C., Braga, Ariadne D., Lopes, Miriam T. P., Takahashi, Jacqueline A., Vieira-Filho, Sidney A. Psychotria viridis: Chemical constituents from leaves and biological properties . anais da academia brasileira de ciencias, 2017, vol. 89, no. 2, p. 927–938. DOI: 10.1590/0001-3765201720160411. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Methanol
Substance:

N,N-DIMETHYLTRYPTAMINE (RF-00004089-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Analytical method - additional description:

spectroscopic (IR, 1H and 13C NMR, HSQC, HMBC and NOESY) and spectrometric (CG-MS and LCMS-ESI-ITTOF) methods
Result unit:

Milligram (G155A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

52.9
Internal remarks:

N,N-dimethyltryptamine in leaves