EFSA Compendium of Botanicals

Draft - work in progress

Polygala sibirica L.

Family:: Polygalaceae
Approval state:: Approved
Number of articles retrieved:: 91
Number of processed references:: 3

Compositions

#1: 4-hydroxy-3,4-dimethoxybenzaldehyde in the aerial parts #2: salicylic acid in the aerial parts #3: triterpene saponines, aerial parts,nmr #4: sibirophenone A, benzophenone derivatives, roots, hplc #5: phenylpropanoids ( 3,4,5-trimethoxycinnamic acid) , roots, hplc

Endpoint Studies

Genotoxicity

Composition #1: Song, Yuelin., Jiang, Yong., Zhou, Sixiang., Tu, Pengfei. Chemical constituents of aerial parts of Polygala sibirica. zhongcaoyao, 2010, vol. 41, no. 1, p. 27–29. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

4-Hydroxy-3,5-dimethoxybenzaldehyde (RF-00001987-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

column chromatography
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

4-hydroxy-3,4-dimethoxybenzaldehyde in the aerial parts

Composition #2: Song, Yuelin., Jiang, Yong., Zhou, Sixiang., Tu, Pengfei. Chemical constituents of aerial parts of Polygala sibirica. zhongcaoyao, 2010, vol. 41, no. 1, p. 27–29. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

Salicylic acid (RF-00000241-VET)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

column chromatography
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

salicylic acid in the aerial parts

Composition #3: Song, Yue-Lin., Zeng, Ke-Wu., Shi, Tian-Xing., Jiang, Yong., Tu, Peng-Fei. Sibiricasaponins A-E, five new triterpenoid saponins from the aerial parts of Polygala sibirica L. . fitoterapia, 2013, vol. 84, p. 295–301. DOI: 10.1016/j.fitote.2012.12.017. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Triterpene saponins Triterpene saponins (RF-00004338-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

triterpene saponines, aerial parts,nmr

Composition #4: Zhou Yu-Hong., Zhang Shui-Ying., Guo Qiang., Chai Xing-Yun., Jiang Yong., Tu Peng-Fei. Chemical investigation of the roots of Polygala sibirica L.. chinese journal of natural medicines, 2014, vol. 12, no. 3, p. 225–228. DOI: 10.3724/SP.J.1009.2014.00225. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Benzophenone derivatives (RF-00010824-PAR)
Additional substance description:

sibirophenone A
Analytical method code:

HPLC with standard detection methods (F019A)
Analytical method - additional description:

NMR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

sibirophenone A, benzophenone derivatives, roots, hplc

Composition #5: Zhou Yu-Hong., Zhang Shui-Ying., Guo Qiang., Chai Xing-Yun., Jiang Yong., Tu Peng-Fei. Chemical investigation of the roots of Polygala sibirica L.. chinese journal of natural medicines, 2014, vol. 12, no. 3, p. 225–228. DOI: 10.3724/SP.J.1009.2014.00225. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

phenylpropanoids (RF-00004367-PAR)
Additional substance description:

3,4,5-trimethoxycinnamic acid
Analytical method code:

HPLC with standard detection methods (F019A)
Analytical method - additional description:

NMR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

phenylpropanoids ( 3,4,5-trimethoxycinnamic acid) , roots, hplc