Draft - work in progress
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- Seneca snakeroot (as plant) // Polygala senega L.
Seneca snakeroot (as plant) // Polygala senega L.
- Family:
- Polygalaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 194
- Number of processed references:
- 7
Composition #1: Pelletier, S. William., Nakamura, Shoshiro. Prosapogenin from Polygala senega and Polygala tenuifolia. tetrahedron letters, 1967, vol. (52), p. 5303–6. .
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Plant part:
Unspecified (A07XD)
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Additional extraction description:
Unspecified
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Substance:
prosapogenin A (RF-00004008-PAR)
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Analytical method code:
Unspecified (F598A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Prosapogenin
Composition #2: Estrada, A., Katselis, GS., Laarveld, B., Barl, B. Isolation and evaluation of immunological adjuvant activities of saponins from Polygala senega L. . comparative immunology microbiology and infectious diseases, 2000, vol. 23, no. 1, p. 27–43. DOI: 10.1016/S0147-9571(99)00020-X.
[
DOI link]
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Methanol, butanol
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Substance:
Saponins (RF-00004333-PAR)
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Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
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Analytical method - additional description:
TLC + HPLC
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
4.5
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Internal remarks:
Saponins (roots)
Composition #3: Ishida, H., Inaoka, Y., Okada, M., Fukushima, M., Fukazawa, H., Tsuji, K. Studies of the active substances in herbs used for hair treatment. III. Isolation of hair-regrowth substances from Polygara senega var. latifolia TORR-et GRAY . biological & pharmaceutical bulletin, 1999, vol. 22, no. 11, p. 1249–1250. .
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
MeOH, BuOH
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Substance:
pentacyclic triterpene saponins (RF-00004334-PAR)
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Additional substance description:
senegin II, senegin III, and senegasaponin b
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Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
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Analytical method - additional description:
NMR, MS, IR, UV
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
senegin II, senegin III, and senegasaponin b in roots
Composition #4: Sun, Hong-Xiang., Xie, Yong., Ye, Yi-Ping. Advances in saponin-based adjuvants. vaccine, 2009, vol. 27, no. 12, p. 1787–1796. DOI: 10.1016/j.vaccine.2009.01.091.
[
DOI link]
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Unspecified
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Substance:
Saponins (RF-00004333-PAR)
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Additional substance description:
Onjisaponin B
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Analytical method code:
Unspecified (F598A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Onjisaponin B
Composition #5: Sun, Hong-Xiang., Xie, Yong., Ye, Yi-Ping. Advances in saponin-based adjuvants. vaccine, 2009, vol. 27, no. 12, p. 1787–1796. DOI: 10.1016/j.vaccine.2009.01.091.
[
DOI link]
-
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Unspecified
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Substance:
Saponins (RF-00004333-PAR)
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Additional substance description:
Onjisaponin A
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Analytical method code:
Unspecified (F598A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Onjisaponin A
Composition #6: Arai, Masayoshi., Hayashi, Asami., Sobou, Mari., Ishida, Shunsuke., Kawachi, Takashi., Kotoku, Naoyuki., Kobayashi, Motomasa. Anti-angiogenic effect of triterpenoidal saponins from Polygala senega. journal of natural medicines, 2011, vol. 65, no. 1, p. 149–156. DOI: 10.1007/s11418-010-0477-7.
[
DOI link]
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Methanol, butanol
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Substance:
pentacyclic triterpene saponins (RF-00004334-PAR)
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Additional substance description:
senegin IV
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Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
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Analytical method - additional description:
NMR, MS
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
senegin IV
Composition #7: Arai, Masayoshi., Hayashi, Asami., Sobou, Mari., Ishida, Shunsuke., Kawachi, Takashi., Kotoku, Naoyuki., Kobayashi, Motomasa. Anti-angiogenic effect of triterpenoidal saponins from Polygala senega. journal of natural medicines, 2011, vol. 65, no. 1, p. 149–156. DOI: 10.1007/s11418-010-0477-7.
[
DOI link]
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Methanol, butanol
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Substance:
pentacyclic triterpene saponins (RF-00004334-PAR)
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Additional substance description:
senegasaponin b
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Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
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Analytical method - additional description:
NMR, MS
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
senegasaponin b
Composition #8: Arai, Masayoshi., Hayashi, Asami., Sobou, Mari., Ishida, Shunsuke., Kawachi, Takashi., Kotoku, Naoyuki., Kobayashi, Motomasa. Anti-angiogenic effect of triterpenoidal saponins from Polygala senega. journal of natural medicines, 2011, vol. 65, no. 1, p. 149–156. DOI: 10.1007/s11418-010-0477-7.
[
DOI link]
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Methanol, butanol
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Substance:
pentacyclic triterpene saponins (RF-00004334-PAR)
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Additional substance description:
senegin III
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Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
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Analytical method - additional description:
NMR, MS
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
senegin III
Composition #9: Arai, Masayoshi., Hayashi, Asami., Sobou, Mari., Ishida, Shunsuke., Kawachi, Takashi., Kotoku, Naoyuki., Kobayashi, Motomasa. Anti-angiogenic effect of triterpenoidal saponins from Polygala senega. journal of natural medicines, 2011, vol. 65, no. 1, p. 149–156. DOI: 10.1007/s11418-010-0477-7.
[
DOI link]
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Methanol, butanol
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Substance:
pentacyclic triterpene saponins (RF-00004334-PAR)
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Additional substance description:
senegin II
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Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
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Analytical method - additional description:
NMR, MS
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
senegin II
Composition #10: Arai, Masayoshi., Hayashi, Asami., Sobou, Mari., Ishida, Shunsuke., Kawachi, Takashi., Kotoku, Naoyuki., Kobayashi, Motomasa. Anti-angiogenic effect of triterpenoidal saponins from Polygala senega. journal of natural medicines, 2011, vol. 65, no. 1, p. 149–156. DOI: 10.1007/s11418-010-0477-7.
[
DOI link]
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Methanol, butanol
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Substance:
pentacyclic triterpene saponins (RF-00004334-PAR)
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Additional substance description:
senegasaponin a
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Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
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Analytical method - additional description:
NMR, MS
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
senegasaponin a
Composition #11: TSUKITANI, Y., KAWANISHI, S., SHOJI, J. STUDIES ON CONSTITUENTS OF SENEGAE RADIX .2. STRUCTURE OF SENEGIN-II, A SAPONIN FROM POLYGALA-SENEGA LINNE VAR LATIFOLIA TORRY AND GRAY . chemical & pharmaceutical bulletin, 1973, vol. 21, no. 4, p. 791–799. .
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
MeOH, BuOH
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Substance:
pentacyclic triterpene saponins (RF-00004334-PAR)
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Additional substance description:
senegin II
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Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
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Analytical method - additional description:
UV, elemental analysis
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
senegin II in roots
Composition #12: TSUKITANI, Y., SHOJI, J. STUDIES ON CONSTITUENTS OF SENEGAE RADIX .3. STRUCTURES OF SENEGIN-III AND SENEGIN-IV, SAPONINS FROM POLYGALA SENEGA LINNE VAR LATIFOLIA TORRY ET GRAY . chemical & pharmaceutical bulletin, 1973, vol. 21, no. 7, p. 1564–1574. .
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
MeOH, BuOH
-
Substance:
pentacyclic triterpene saponins (RF-00004334-PAR)
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Additional substance description:
senegin III and senegin IV
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Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
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Analytical method - additional description:
NMR, UV
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
senegin III and senegin IV in roots