EFSA Compendium of Botanicals

Draft - work in progress

Platycladus orientalis (L.) Franco // Thuja orientalis L.

Family:: Cupressaceae
Approval state:: Approved
Number of articles retrieved:: 1918
Number of processed references:: 5

Compositions

#1: alfa-thujone, aerial parts #2: beta-thujone, aerial parts #3: camphor,aerial parts #4: fenchone, aerial parts #5: labdane diterpenes, seeds #6: pinusolide, leaves #7: alpha-cedrol,fruit #8: myrcene, fruit #9: myrcene, fruit #10: alpha-cedrol, leaves #11: alpha-cedrol, stem #12: cedrol, leaves #13: myrcene, leaves #14: myrcene, stem

Endpoint Studies

Genotoxicity

Composition #1: Chizzola, R., Hochsteiner, W., Hajek, S. GC analysis of essential oils in the rumen fluid after incubation of Thuja orientalis twigs in the Rusitec system . research in veterinary science, 2004, vol. 76, no. 1, p. 77–82. DOI: 10.1016/j.rvsc.2003.07.001. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

alpha-thujone (RF-00003676-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Numerical Value (VAL)
Value (concentration, content):

52.28
Internal remarks:

alfa-thujone, aerial parts

Composition #2: Chizzola, R., Hochsteiner, W., Hajek, S. GC analysis of essential oils in the rumen fluid after incubation of Thuja orientalis twigs in the Rusitec system . research in veterinary science, 2004, vol. 76, no. 1, p. 77–82. DOI: 10.1016/j.rvsc.2003.07.001. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

beta-thujone (RF-00003712-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Numerical Value (VAL)
Value (concentration, content):

10.3
Internal remarks:

beta-thujone, aerial parts

Composition #3: Chizzola, R., Hochsteiner, W., Hajek, S. GC analysis of essential oils in the rumen fluid after incubation of Thuja orientalis twigs in the Rusitec system . research in veterinary science, 2004, vol. 76, no. 1, p. 77–82. DOI: 10.1016/j.rvsc.2003.07.001. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

(-)-camphor (RF-00003469-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.3
Internal remarks:

camphor,aerial parts

Composition #4: Chizzola, R., Hochsteiner, W., Hajek, S. GC analysis of essential oils in the rumen fluid after incubation of Thuja orientalis twigs in the Rusitec system . research in veterinary science, 2004, vol. 76, no. 1, p. 77–82. DOI: 10.1016/j.rvsc.2003.07.001. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

fenchone (RF-00003814-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Numerical Value (VAL)
Value (concentration, content):

12.25
Internal remarks:

fenchone, aerial parts

Composition #5: Ren, X. -Y., Ye, Y. Labdane diterpenes from the seeds of Platycladus orientalis. journal of asian natural products research, 2006, vol. 8, no. 8, p. 677–682. DOI: 10.1080/10286020500246584. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

petroleum ether
Substance:

labdane diterpenes (RF-00004392-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Analytical method - additional description:

NMR, MS, IR, X-ray crystallography
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

labdane diterpenes, seeds

Composition #6: Kim, Jin-Young., Kim, Hyun Jung., Kim, Sung-Moo., Park, Kyung-Ran., Jang, Hyeung-Jin., Lee, Eun Ha., Jung, Sang Hoon., Ahn, Kwang Seok. Methylene chloride fraction of the leaves of Thuja orientalis inhibits in vitro inflammatory biomarkers by blocking NF-kappa B and p38 MAPK signaling and protects mice from lethal endotoxemia . journal of ethnopharmacology, 2011, vol. 133, no. 2, p. 687–695. DOI: 10.1016/j.jep.2010.10.051. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

labdane diterpenes (RF-00004392-PAR)
Additional substance description:

pinusolide (Diterpene lactone)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Analytical method - additional description:

HPLC-DAD-MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

pinusolide, leaves

Composition #7: Hashemi, Seyed Mehdi., Safavi, Seyed Ali. CHEMICAL CONSTITUENTS AND TOXICITY OF ESSENTIAL OILS OF ORIENTAL ARBORVITAE, Platycladus orientalis (L.) FRANCO, AGAINST THREE STORED-PRODUCT BEETLES . chilean journal of agricultural research, 2012, vol. 72, no. 2, p. 188–194. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

alpha-cedrol (RF-00003645-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Numerical Value (VAL)
Value (concentration, content):

6.9
Internal remarks:

alpha-cedrol,fruit

Composition #8: Hashemi, Seyed Mehdi., Safavi, Seyed Ali. CHEMICAL CONSTITUENTS AND TOXICITY OF ESSENTIAL OILS OF ORIENTAL ARBORVITAE, Platycladus orientalis (L.) FRANCO, AGAINST THREE STORED-PRODUCT BEETLES . chilean journal of agricultural research, 2012, vol. 72, no. 2, p. 188–194. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.8
Internal remarks:

myrcene, fruit

Composition #9: Hashemi, Seyed Mehdi., Safavi, Seyed Ali. CHEMICAL CONSTITUENTS AND TOXICITY OF ESSENTIAL OILS OF ORIENTAL ARBORVITAE, Platycladus orientalis (L.) FRANCO, AGAINST THREE STORED-PRODUCT BEETLES . chilean journal of agricultural research, 2012, vol. 72, no. 2, p. 188–194. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.8
Internal remarks:

myrcene, fruit

Composition #10: Hashemi, Seyed Mehdi., Safavi, Seyed Ali. CHEMICAL CONSTITUENTS AND TOXICITY OF ESSENTIAL OILS OF ORIENTAL ARBORVITAE, Platycladus orientalis (L.) FRANCO, AGAINST THREE STORED-PRODUCT BEETLES . chilean journal of agricultural research, 2012, vol. 72, no. 2, p. 188–194. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

alpha-cedrol (RF-00003645-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Numerical Value (VAL)
Value (concentration, content):

14.9
Internal remarks:

alpha-cedrol, leaves

Composition #11: Kim, Min-Gi., Lee, Hoi-Seon. Growth-inhibiting effects and chemical composition of essential oils extracted from Platycladus orientalis leaves and stems toward human intestinal bacteria . food science and biotechnology, 2015, vol. 24, no. 2, p. 427–431. DOI: 10.1007/s10068-015-0056-5. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

alpha-cedrol (RF-00003645-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Numerical Value (VAL)
Value (concentration, content):

6.1
Internal remarks:

alpha-cedrol, stem

Composition #12: Kim, Min-Gi., Lee, Hoi-Seon. Growth-inhibiting effects and chemical composition of essential oils extracted from Platycladus orientalis leaves and stems toward human intestinal bacteria . food science and biotechnology, 2015, vol. 24, no. 2, p. 427–431. DOI: 10.1007/s10068-015-0056-5. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

alpha-cedrol (RF-00003645-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Numerical Value (VAL)
Value (concentration, content):

11.3
Internal remarks:

cedrol, leaves

Composition #13: Kim, Min-Gi., Lee, Hoi-Seon. Growth-inhibiting effects and chemical composition of essential oils extracted from Platycladus orientalis leaves and stems toward human intestinal bacteria . food science and biotechnology, 2015, vol. 24, no. 2, p. 427–431. DOI: 10.1007/s10068-015-0056-5. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.5
Internal remarks:

myrcene, leaves

Composition #14: Kim, Min-Gi., Lee, Hoi-Seon. Growth-inhibiting effects and chemical composition of essential oils extracted from Platycladus orientalis leaves and stems toward human intestinal bacteria . food science and biotechnology, 2015, vol. 24, no. 2, p. 427–431. DOI: 10.1007/s10068-015-0056-5. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.6
Internal remarks:

myrcene, stem