EFSA Compendium of Botanicals

Draft - work in progress

Burnet saxifrage (as plant) // Pimpinella saxifraga L.

Family:: Apiaceae
Approval state:: Approved
Number of articles retrieved:: 172
Number of processed references:: 3

Compositions

#1: Prunetin - leaves #2: genistein - leaves #3: sissotrin - leaves #4: Myrcene in fruits #5: pimpinellin - root #6: xanthotoxin - root #7: umbelliferone - root #8: isopimpinellin - root #9: bergapten - root

Endpoint Studies

Genotoxicity

Composition #1: Abdulmanea, Khaled., Prokudina, Elena A., Lankova, Petra., Vanickova, Lucie., Koblovska, Radka., Zeleny, Vaclav., Lapcik, Oldrich. Immunochemical and HPLC identification of isoflavonoids in the Apiaceae family. biochemical systematics and ecology, 2012, vol. 45, p. 237–243. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Prunetin (RF-00011016-PAR)
Analytical method code:

Mass Spectroscopy and hyphenated methods without chromatography (F063A)
Analytical method - additional description:

HPLC-MS
Result unit:

Milligram/kilogram (G061A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

6.1
Internal remarks:

Prunetin - leaves

Composition #2: Abdulmanea, Khaled., Prokudina, Elena A., Lankova, Petra., Vanickova, Lucie., Koblovska, Radka., Zeleny, Vaclav., Lapcik, Oldrich. Immunochemical and HPLC identification of isoflavonoids in the Apiaceae family. biochemical systematics and ecology, 2012, vol. 45, p. 237–243. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

genistein (RF-00000297-NTR)
Analytical method code:

Mass Spectroscopy and hyphenated methods without chromatography (F063A)
Analytical method - additional description:

HPLC-MS
Result unit:

Milligram/kilogram (G061A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

40.1
Internal remarks:

genistein - leaves

Composition #3: Abdulmanea, Khaled., Prokudina, Elena A., Lankova, Petra., Vanickova, Lucie., Koblovska, Radka., Zeleny, Vaclav., Lapcik, Oldrich. Immunochemical and HPLC identification of isoflavonoids in the Apiaceae family. biochemical systematics and ecology, 2012, vol. 45, p. 237–243. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Sissotrin (RF-00011021-PAR)
Analytical method code:

Mass Spectroscopy and hyphenated methods without chromatography (F063A)
Analytical method - additional description:

HPLC-MS
Result unit:

Milligram/kilogram (G061A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

7.2
Internal remarks:

sissotrin - leaves

Composition #4: Tabanca, N., Demirci, B., Ozek, T., Kirimer, N., Baser, KHC., Bedir, E., Khan, IA., Wedge, DE. Gas chromatographic-mass spectrometric analysis of essential oils from Pimpinella species gathered from Central and Northern Turkey . journal of chromatography a, 2006, vol. 1117, no. 2, p. 194–205. DOI: 10.1016/j.chroma.2006.03.075. [DOI link]

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

14.1
Internal remarks:

Myrcene in fruits

Composition #5: Oniszczuk, A., Waksmundzka-Hajnos, M., Podgorski, R., Nowak, R., Zukiewicz-Sobczak, W., Blicharski, T. Comparison of Matrix Solid-Phase Dispersion and Liquid-Solid Extraction Methods Followed by Solid-Phase Extraction in the Analysis of Selected Furanocoumarins from Pimpinella Roots by HPLC-DAD . acta chromatographica, 2015, vol. 27, no. 4, p. 687–696. DOI: 10.1556/AChrom.27.2015.4.7. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

pimpinellin (RF-00003997-PAR)
Analytical method code:

HPLC-DAD (F587A)
Result unit:

Microgram/gram (G049A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1113.65-1560.58
Internal remarks:

pimpinellin - root

Composition #6: Oniszczuk, A., Waksmundzka-Hajnos, M., Podgorski, R., Nowak, R., Zukiewicz-Sobczak, W., Blicharski, T. Comparison of Matrix Solid-Phase Dispersion and Liquid-Solid Extraction Methods Followed by Solid-Phase Extraction in the Analysis of Selected Furanocoumarins from Pimpinella Roots by HPLC-DAD . acta chromatographica, 2015, vol. 27, no. 4, p. 687–696. DOI: 10.1556/AChrom.27.2015.4.7. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Xanthotoxol (RF-00011114-PAR)
Additional substance description:

Xanthotoxin
Analytical method code:

HPLC-DAD (F587A)
Result unit:

Microgram/gram (G049A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

137.99-205.44
Internal remarks:

xanthotoxin - root

Composition #7: Oniszczuk, A., Waksmundzka-Hajnos, M., Podgorski, R., Nowak, R., Zukiewicz-Sobczak, W., Blicharski, T. Comparison of Matrix Solid-Phase Dispersion and Liquid-Solid Extraction Methods Followed by Solid-Phase Extraction in the Analysis of Selected Furanocoumarins from Pimpinella Roots by HPLC-DAD . acta chromatographica, 2015, vol. 27, no. 4, p. 687–696. DOI: 10.1556/AChrom.27.2015.4.7. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

umbelliferone (RF-00004096-PAR)
Analytical method code:

HPLC-DAD (F587A)
Result unit:

Microgram/gram (G049A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

708.48-1155.16
Internal remarks:

umbelliferone - root

Composition #8: Oniszczuk, A., Waksmundzka-Hajnos, M., Podgorski, R., Nowak, R., Zukiewicz-Sobczak, W., Blicharski, T. Comparison of Matrix Solid-Phase Dispersion and Liquid-Solid Extraction Methods Followed by Solid-Phase Extraction in the Analysis of Selected Furanocoumarins from Pimpinella Roots by HPLC-DAD . acta chromatographica, 2015, vol. 27, no. 4, p. 687–696. DOI: 10.1556/AChrom.27.2015.4.7. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Isopimpinellin (RF-00003784-PAR)
Analytical method code:

HPLC-DAD (F587A)
Result unit:

Microgram/gram (G049A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1416.37-1971.2
Internal remarks:

isopimpinellin - root

Composition #9: Oniszczuk, A., Waksmundzka-Hajnos, M., Podgorski, R., Nowak, R., Zukiewicz-Sobczak, W., Blicharski, T. Comparison of Matrix Solid-Phase Dispersion and Liquid-Solid Extraction Methods Followed by Solid-Phase Extraction in the Analysis of Selected Furanocoumarins from Pimpinella Roots by HPLC-DAD . acta chromatographica, 2015, vol. 27, no. 4, p. 687–696. DOI: 10.1556/AChrom.27.2015.4.7. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Bergapten (RF-00003837-PAR)
Analytical method code:

HPLC-DAD (F587A)
Result unit:

Microgram/gram (G049A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

520.68-730.7
Internal remarks:

bergapten - root