EFSA Compendium of Botanicals

Draft - work in progress

Picramnia antidesma Sw.

Family:: Picramniaceae
Approval state:: Approved
Number of articles retrieved:: 11
Number of processed references:: 5

Compositions

#1: anthraquinone derivatives #2: Chrysophanol in roots #3: Emodin in roots #4: 7-hydroxycoumarin in roots #5: oxanthrones: mayoside and saroside in stem #6: anthraquinone derivatives in roots #7: Picramniosides in leaves #8: Aloe-emodin and derivatives in leaves

Endpoint Studies

Genotoxicity

Composition #1: Jacobo-Herrera, N.J., Jacobo-Herrera, F.E., Zentella-Dehesa, A., Andrade-Cetto, A., Heinrich, M., Pérez-Plasencia, C. Medicinal plants used in Mexican traditional medicine for the treatment of colorectal cancer. journal of ethnopharmacology, 2016, vol. 179, p. 391–402. DOI: 10.1016/j.jep.2015.12.042. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

anthraquinones (RF-00004343-PAR)
Additional substance description:

Uveoside and derivatives, Picramniosides D and E
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

anthraquinone derivatives

Composition #2: Hernandez-Medel, MD., Garcia-Salmones, I., Santillan, R., Trigos, A. An anthrone from Picramnia antidesma. phytochemistry, 1998, vol. 49, no. 8, p. 2599–2601. DOI: 10.1016/S0031-9422(98)00383-5. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

chloroform
Substance:

chrysophanol (RF-00003737-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

column chromathography on silica gel
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Chrysophanol in roots

Composition #3: Hernandez-Medel, MD., Garcia-Salmones, I., Santillan, R., Trigos, A. An anthrone from Picramnia antidesma. phytochemistry, 1998, vol. 49, no. 8, p. 2599–2601. DOI: 10.1016/S0031-9422(98)00383-5. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

chloroform
Substance:

Emodin (RF-00003798-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

column chromathography on silica gel
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Emodin in roots

Composition #4: Hernandez-Medel, MD., Garcia-Salmones, I., Santillan, R., Trigos, A. An anthrone from Picramnia antidesma. phytochemistry, 1998, vol. 49, no. 8, p. 2599–2601. DOI: 10.1016/S0031-9422(98)00383-5. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

chloroform
Substance:

Coumarin (RF-00000370-TOX)
Additional substance description:

7-hydroxycoumarin
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

column chromathography on silica gel
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

7-hydroxycoumarin in roots

Composition #5: Hernandez-Medel, MD., Ramirez-Corzas, CO., Rivera-Dominguez, MN., Ramirez-Mendez, J., Santillan, R., Rojas-Lima, S. Diastereomeric C-glycosyloxanthrones from picramnia antidesma. phytochemistry, 1999, vol. 50, no. 8, p. 1379–1383. DOI: 10.1016/S0031-9422(98)00354-9. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

anthrones (RF-00010811-PAR)
Additional substance description:

oxanthrones: mayoside and saroside
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Analytical method - additional description:

X-ray
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

oxanthrones: mayoside and saroside in stem

Composition #6: Hernandez-Medel, MD., Pereda-Miranda, R. Cytotoxic anthraquinone derivatives from Picramnia antidesma. planta medica, 2002, vol. 68, no. 6, p. 556–558. DOI: 10.1055/s-2002-32562. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Et2O, MeOH; extraction from root bark
Substance:

anthraquinones (RF-00004343-PAR)
Additional substance description:

anthraquinone derivatives: saroside, mayoside
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

anthraquinone derivatives in roots

Composition #7: SOLIS, PN., RAVELO, AG., GONZALEZ, AG., GUPTA, MP., PHILLIPSON, JD. BIOACTIVE ANTHRAQUINONE GLYCOSIDES FROM PICRAMNIA-ANTIDESMA SSP FESSONIA. phytochemistry, 1995, vol. 38, no. 2, p. 477–480. DOI: 10.1016/0031-9422(94)00598-N. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

picramnioside A (RF-00003539-PAR)
Additional substance description:

Picramniosides A, B and C
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Picramniosides in leaves

Composition #8: SOLIS, PN., RAVELO, AG., GONZALEZ, AG., GUPTA, MP., PHILLIPSON, JD. BIOACTIVE ANTHRAQUINONE GLYCOSIDES FROM PICRAMNIA-ANTIDESMA SSP FESSONIA. phytochemistry, 1995, vol. 38, no. 2, p. 477–480. DOI: 10.1016/0031-9422(94)00598-N. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Aloe-emodin (RF-00003670-PAR)
Additional substance description:

aloe-emodin and aloe-emodin anthrone
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Aloe-emodin and derivatives in leaves