Draft - work in progress
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- Field bean (fresh seeds) // Phaseolus vulgaris L.
Field bean (fresh seeds) // Phaseolus vulgaris L.
- Family:
- Fabaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 51697
- Number of processed references:
- 7
Composition #1: Kupper, Jacqueline., Reichert, Cornelia. Intoxications with plants .. therapeutische umschau. revue therapeutique, 2009, vol. 66, no. 5, p. 343–8. DOI: 10.1024/0040-5930.66.5.343.
[
DOI link]
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Plant part:
Unspecified (A07XD)
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Substance:
phasin (RF-00003987-PAR)
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Analytical method code:
Unspecified (F598A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Phasin in unspecified plant part
Composition #2: Aparicio-Fernandez, X., Manzo-Bonilla, L., Loarca-Pina, GF. Comparison of antimutagenic activity of phenolic compounds in newly harvested and stored common beans Phaseolus vulgaris against aflatoxin B1. journal of food science, 2005, vol. 70, no. 1, p. S73–S78. DOI: 10.1111/j.1365-2621.2005.tb09068.x.
[
DOI link]
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Plant part:
Seed (as part-nature) (A066P)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
methanol
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Substance:
Tannins (RF-00004337-PAR)
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Substance used for equivalence:
Catechin (RF-00010400-PAR)
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Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
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Result unit:
Milligram/gram (G060A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
586-859.84
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Internal remarks:
tannin in seed extract
Composition #3: Aparicio-Fernandez, X., Manzo-Bonilla, L., Loarca-Pina, GF. Comparison of antimutagenic activity of phenolic compounds in newly harvested and stored common beans Phaseolus vulgaris against aflatoxin B1. journal of food science, 2005, vol. 70, no. 1, p. S73–S78. DOI: 10.1111/j.1365-2621.2005.tb09068.x.
[
DOI link]
-
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Plant part:
Seed (as part-nature) (A066P)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
methanol
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Substance:
Tannins (RF-00004337-PAR)
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Substance used for equivalence:
Catechin (RF-00010400-PAR)
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Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
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Result unit:
Milligram/gram (G060A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
59.74-222.41
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Internal remarks:
tannin in seeds coat
Endpoint study
#1: Jayne-Williams, D. J., Burgess, C. D. Toxicity of navy beans (Phaseolus vulgaris) for Japanese quail (Coturnix coturnix). journal of applied bacteriology, 1974, vol. 37, no. 1, p. 149–69. .
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Study relevance:
Animal (target species) health
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Plant part:
Seed (as part-nature) (A066P)
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Type of toxicological test:
short-term toxicity (CHD017TT)
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Tested organism:
Japanese Quail (as animal) (A0CNJ)
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Route of exposure:
ORAL: FEED (OECD2230PL)
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Unit of exposure duration:
Day (G134A)
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Number of organisms dosed:
11
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Endpoint measured:
Dose level (CHD014EP)
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Concentration unit:
Percent (G138A)
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Effect description:
Birds died already 1 day after exposure, all birds died by the fifth day
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Effect or parameter linked to the endpoint:
mortality (CHD010BE)
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Internal remarks:
Mortality in quail
Endpoint study
#2: Assis, T.S., Medeiros, R.M., de Araújo, J.A.S., Dantas, A.F.M., Riet-Correa, F. Plant poisonings in ruminants and equidae in the Sertão of Paraiba, Brazil Intoxicações por plantas em ruminantes e equídeos no Sertão Paraibano. pesquisa veterinaria brasileira, 2009, vol. 29, no. 11, p. 919–924. .
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Study relevance:
Animal (target species) health
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Plant part:
Seed (as part-nature) (A066P)
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Type of toxicological test:
not reported (CHD015TT)
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Tested organism:
Cattle (as animal) (A057E)
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Control groups used:
no data
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Endpoint measured:
Dose not reported (CHD066EP)
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Critical effect:
Digestive (TOX18A)
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Target tissue:
digestive: Stomach (TT027A)
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Effect description:
Peels of beans associated with ruminal impactation in cattle
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Effect or parameter linked to the endpoint:
other (CHD003BE)
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Internal remarks:
Peels of beans associated with ruminal impactation in cattle
Endpoint study
#3: Kuete, V. Physical, Hematological, and Histopathological Signs of Toxicity Induced by African Medicinal Plants. toxicological survey of african medicinal plants, 2014, p. 635–657. DOI: 10.1016/B978-0-12-800018-2.00022-4.
[
DOI link]
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Study relevance:
Human health
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Plant part:
Seed (as part-nature) (A066P)
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Additional plant/substance description:
phytohemagglutinin
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Type of toxicological test:
not reported (CHD015TT)
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Tested organism:
Human (as organism) (A056J)
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Endpoint measured:
Dose not reported (CHD066EP)
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Target tissue:
Digestive (TT002A)
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Effect description:
nausea, vomiting, and diarrhea
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Effect or parameter linked to the endpoint:
other (CHD003BE)
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Internal remarks:
nausea, vomiting, and diarrhea after the ingestion of beans
Endpoint study
#4: Tuxen, M K., Nielsen, H V., Birgens, H. Poisoning by kidney beans (Phaseolus vulgaris) .. ugeskrift for laeger, 1991, vol. 153, no. 51, p. 3628–9. .
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Study relevance:
Human health
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Plant part:
Seed (as part-nature) (A066P)
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Type of toxicological test:
case report (CHD060TT)
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Tested organism:
Human (as organism) (A056J)
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Number of organisms dosed:
2
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Endpoint measured:
Dose not reported (CHD066EP)
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Critical effect:
Digestive (TOX18A)
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Target tissue:
Digestive (TT002A)
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Effect description:
poisoning including diarrhoea, vomiting, muscular pain, rhabdomyolysis and toxic myocarditis
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Effect or parameter linked to the endpoint:
other (CHD003BE)
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Internal remarks:
poisoning including diarrhoea, vomiting, muscular pain, rhabdomyolysis and toxic myocarditis after consumption of raw beans
Endpoint study
#5: Liener, I E. Naturally occurring toxicants in foods and their significance in the human diet.. archives of toxicology. supplement. = archiv fur toxikologie. supplement, 1983, vol. 6, p. 153–66. .
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Study relevance:
Human health
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Plant part:
Seed (as part-nature) (A066P)
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Additional plant/substance description:
PHYTOHEMAGGLUTININ
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Type of toxicological test:
not reported (CHD015TT)
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Tested organism:
Rat (as animal) (A0CNV)
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Control groups used:
no data
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Endpoint measured:
Concentration level (CHD013EP)
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Concentration unit:
Percent (G138A)
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Effect concentration:
0.5-2
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Effect description:
Inhibitory effect on growth
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Effect or parameter linked to the endpoint:
growth (CHD009BE)
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Internal remarks:
inhibitory effect of the lectin on the growth of rats