Draft - work in progress
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- Peucedanum officinale L.
Peucedanum officinale L.
- Family:
- Apiaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 56
- Number of processed references:
- 7
Composition #1: Kubeczka, Karl Heinz., Ullmann, Isolde. The essential oil from Peucedanum officinale leaves. rivista italiana eppos, 1981, vol. 63, no. 5, p. 265–70. .
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Substance:
myristicin (RF-00003941-PAR)
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Additional substance description:
myristicin and trans-isomyristicin
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Analytical method code:
GC-MS (F046A)
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Analytical method - additional description:
IR, NMR
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Myristicin and trans-isomyristicin in leaf essential oil
Composition #2: Roman, I., Rusu, M.A., Puicǎ, C., Deliu, C. Some histoenzymological (Histochemical) and biochemical changes induced by peucedanum herbal extracts upon the liver and kidney in rats. annals of the romanian society for cell biology, 2011, vol. 16, no. 2, p. 69–73. .
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
ethylic alcohol (stems with leaves and flowers)
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Substance:
coumarins (RF-00004351-PAR)
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Analytical method code:
Unspecified (F598A)
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Result unit:
Microgram/millilitre (G052A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
230
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Internal remarks:
coumarins in aerial parts (stems with leaves and flowers)
Composition #3: Jaimand, K., Sharifi, E. Ashorabadi., Dini, M. Chemical constituents of the leaf and seed oils of Peucedanum officinale L. cultivated in Iran . journal of essential oil research, 2006, vol. 18, no. 6, p. 670–671. .
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Plant part:
Seed (as part-nature) (A066P)
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Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Additional extraction description:
hydrodistillation
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Substance:
alpha-thujone (RF-00003676-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
1.2
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Internal remarks:
Alpha-thujone in seeds
Composition #4: Jaimand, K., Sharifi, E. Ashorabadi., Dini, M. Chemical constituents of the leaf and seed oils of Peucedanum officinale L. cultivated in Iran . journal of essential oil research, 2006, vol. 18, no. 6, p. 670–671. .
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Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Additional extraction description:
hydrodistillation
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Substance:
Carvone (RF-0538-001-PPP)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
1.3
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Internal remarks:
Carvone in leaves
Composition #5: Jaimand, K., Sharifi, E. Ashorabadi., Dini, M. Chemical constituents of the leaf and seed oils of Peucedanum officinale L. cultivated in Iran . journal of essential oil research, 2006, vol. 18, no. 6, p. 670–671. .
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Plant part:
Seed (as part-nature) (A066P)
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Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Additional extraction description:
hydrodistillation
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Substance:
fenchone (RF-00003814-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
32
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Internal remarks:
Fenchone in seeds
Composition #6: Jaimand, K., Sharifi, E. Ashorabadi., Dini, M. Chemical constituents of the leaf and seed oils of Peucedanum officinale L. cultivated in Iran . journal of essential oil research, 2006, vol. 18, no. 6, p. 670–671. .
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Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Additional extraction description:
hydrodistillation
-
Substance:
fenchone (RF-00003814-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
27.7
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Internal remarks:
Fenchone in leaves
Composition #7: Jaimand, K., Sharifi, E. Ashorabadi., Dini, M. Chemical constituents of the leaf and seed oils of Peucedanum officinale L. cultivated in Iran . journal of essential oil research, 2006, vol. 18, no. 6, p. 670–671. .
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Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
-
Additional extraction description:
hydrodistillation
-
Substance:
alpha-thujone (RF-00003676-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
3.3
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Internal remarks:
Alpha-thujone in leaves
Composition #8: Jaimand, K., Sharifi, E. Ashorabadi., Dini, M. Chemical constituents of the leaf and seed oils of Peucedanum officinale L. cultivated in Iran . journal of essential oil research, 2006, vol. 18, no. 6, p. 670–671. .
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Additional extraction description:
hydrodistillation
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Substance:
elemicin (RF-00003787-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
3.9
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Internal remarks:
Elimicin in leaves
Composition #9: Kapetanos, Chrysostomos., Karioti, Anastasia., Bojovic, Srdjan., Marin, Petar., Veljic, Milan., Skaltsa, Helen. Chemical and principal-component analyses of the essential oils of apioideae taxa (Apiaceae) from central Balkan . chemistry & biodiversity, 2008, vol. 5, no. 1, p. 101–119. DOI: 10.1002/cbdv.200890000.
[
DOI link]
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Plant part:
Unspecified (A07XD)
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Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Additional extraction description:
hydrodistillation
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Substance:
myrcene (RF-00003503-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
5.3
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Internal remarks:
myrcene in essential oil
Composition #10: Figueredo, Gilles., Chalchat, Jean-Claude., Petrovic, Silvana., Maksimovic, Zoran., Gorunovic, Momcilo., Boza, Pal., Radic, Jelena. Composition of Essential Oils of Flowers, Leaves, Stems and Rhizome of Peucedanum officinale L. (Apiaceae) . journal of essential oil research, 2009, vol. 21, no. 2, p. 123–126. .
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Plant part:
Stem / stalk (as part-nature) (A067S)
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Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Additional extraction description:
hydrodistillation
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Substance:
myrcene (RF-00003503-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
11.7
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Internal remarks:
Myrcene in stems
Composition #11: Figueredo, Gilles., Chalchat, Jean-Claude., Petrovic, Silvana., Maksimovic, Zoran., Gorunovic, Momcilo., Boza, Pal., Radic, Jelena. Composition of Essential Oils of Flowers, Leaves, Stems and Rhizome of Peucedanum officinale L. (Apiaceae) . journal of essential oil research, 2009, vol. 21, no. 2, p. 123–126. .
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Plant part:
Flower (as part-nature) (A067B)
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Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Additional extraction description:
hydrodistillation
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Substance:
myrcene (RF-00003503-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
22
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Internal remarks:
Myrcene in flowers
Composition #12: Figueredo, Gilles., Chalchat, Jean-Claude., Petrovic, Silvana., Maksimovic, Zoran., Gorunovic, Momcilo., Boza, Pal., Radic, Jelena. Composition of Essential Oils of Flowers, Leaves, Stems and Rhizome of Peucedanum officinale L. (Apiaceae) . journal of essential oil research, 2009, vol. 21, no. 2, p. 123–126. .
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Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
-
Additional extraction description:
hydrodistillation
-
Substance:
myrcene (RF-00003503-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
9.5
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Internal remarks:
Myrcene in leaves
Composition #13: Gird, Cerasela Elena., Costea, Teodora., Nencu, Ioana., Popescu, Maria Lidia., Dutu, Ligia Elena. PHYTOCHEMICAL AND PHYTOBIOLOGICAL RESEARCH UPON AERIAL PARTS AND SEEDS FROM PEUCEDANUM OFFICINALE L. . farmacia, 2015, vol. 63, no. 2, p. 247–253. .
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
ether and ethanol
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Substance:
Bergapten (RF-00003837-PAR)
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Additional substance description:
Bergapten and 8-methoxypsoralen
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Analytical method code:
Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Bergapten and 8-methoxypsoralen in aerial parts
Composition #14: Gird, Cerasela Elena., Costea, Teodora., Nencu, Ioana., Popescu, Maria Lidia., Dutu, Ligia Elena. PHYTOCHEMICAL AND PHYTOBIOLOGICAL RESEARCH UPON AERIAL PARTS AND SEEDS FROM PEUCEDANUM OFFICINALE L. . farmacia, 2015, vol. 63, no. 2, p. 247–253. .
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
ether and ethanol
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Substance:
Bergapten (RF-00003837-PAR)
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Analytical method code:
Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Bergapten in aerial parts
Composition #15: HADACEK, F., MULLER, C., WERNER, A., GREGER, H., PROKSCH, P. ANALYSIS, ISOLATION AND INSECTICIDAL ACTIVITY OF LINEAR FURANOCOUMARINS AND OTHER COUMARIN DERIVATIVES FROM PEUCEDANUM (APIACEAE, APIOIDEAE) . journal of chemical ecology, 1994, vol. 20, no. 8, p. 2035–2054. DOI: 10.1007/BF02066241.
[
DOI link]
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
petroleum ether-diethyl ether OR hexane-diethyl ether-methanol
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Substance:
8-methoxy-peucedanin (RF-00003853-PAR)
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Analytical method code:
HPLC-UV (F021A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
8 methoxy-peucedanin in roots
Composition #16: HADACEK, F., MULLER, C., WERNER, A., GREGER, H., PROKSCH, P. ANALYSIS, ISOLATION AND INSECTICIDAL ACTIVITY OF LINEAR FURANOCOUMARINS AND OTHER COUMARIN DERIVATIVES FROM PEUCEDANUM (APIACEAE, APIOIDEAE) . journal of chemical ecology, 1994, vol. 20, no. 8, p. 2035–2054. DOI: 10.1007/BF02066241.
[
DOI link]
-
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
petroleum ether-diethyl ether OR hexane-diethyl ether-methanol
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Substance:
isoimperatorin (RF-00003880-PAR)
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Analytical method code:
HPLC-UV (F021A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
isoimperatorin in roots
Composition #17: HADACEK, F., MULLER, C., WERNER, A., GREGER, H., PROKSCH, P. ANALYSIS, ISOLATION AND INSECTICIDAL ACTIVITY OF LINEAR FURANOCOUMARINS AND OTHER COUMARIN DERIVATIVES FROM PEUCEDANUM (APIACEAE, APIOIDEAE) . journal of chemical ecology, 1994, vol. 20, no. 8, p. 2035–2054. DOI: 10.1007/BF02066241.
[
DOI link]
-
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Plant part:
Fruit unspecified (as part-nature) (A067D)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
petroleum ether-diethyl ether OR hexane-diethyl ether-methanol
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Substance:
Bergapten (RF-00003837-PAR)
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Analytical method code:
HPLC-UV (F021A)
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
bergabten in fruits
Composition #18: HADACEK, F., MULLER, C., WERNER, A., GREGER, H., PROKSCH, P. ANALYSIS, ISOLATION AND INSECTICIDAL ACTIVITY OF LINEAR FURANOCOUMARINS AND OTHER COUMARIN DERIVATIVES FROM PEUCEDANUM (APIACEAE, APIOIDEAE) . journal of chemical ecology, 1994, vol. 20, no. 8, p. 2035–2054. DOI: 10.1007/BF02066241.
[
DOI link]
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
petroleum ether-diethyl ether OR hexane-diethyl ether-methanol
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Substance:
peucedanin (RF-00003984-PAR)
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Analytical method code:
HPLC-UV (F021A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
peucedanin in roots
Composition #19: HADACEK, F., MULLER, C., WERNER, A., GREGER, H., PROKSCH, P. ANALYSIS, ISOLATION AND INSECTICIDAL ACTIVITY OF LINEAR FURANOCOUMARINS AND OTHER COUMARIN DERIVATIVES FROM PEUCEDANUM (APIACEAE, APIOIDEAE) . journal of chemical ecology, 1994, vol. 20, no. 8, p. 2035–2054. DOI: 10.1007/BF02066241.
[
DOI link]
-
-
Plant part:
Fruit unspecified (as part-nature) (A067D)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
petroleum ether-diethyl ether OR hexane-diethyl ether-methanol
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Substance:
Isopimpinellin (RF-00003784-PAR)
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Analytical method code:
HPLC-UV (F021A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
isopimpinellin in fruits
Composition #20: HADACEK, F., MULLER, C., WERNER, A., GREGER, H., PROKSCH, P. ANALYSIS, ISOLATION AND INSECTICIDAL ACTIVITY OF LINEAR FURANOCOUMARINS AND OTHER COUMARIN DERIVATIVES FROM PEUCEDANUM (APIACEAE, APIOIDEAE) . journal of chemical ecology, 1994, vol. 20, no. 8, p. 2035–2054. DOI: 10.1007/BF02066241.
[
DOI link]
-
-
Plant part:
Fruit unspecified (as part-nature) (A067D)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
petroleum ether-diethyl ether OR hexane-diethyl ether-methanol
-
Substance:
peucedanin (RF-00003984-PAR)
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Analytical method code:
HPLC-UV (F021A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
peucedanin in fruits
Composition #21: HADACEK, F., MULLER, C., WERNER, A., GREGER, H., PROKSCH, P. ANALYSIS, ISOLATION AND INSECTICIDAL ACTIVITY OF LINEAR FURANOCOUMARINS AND OTHER COUMARIN DERIVATIVES FROM PEUCEDANUM (APIACEAE, APIOIDEAE) . journal of chemical ecology, 1994, vol. 20, no. 8, p. 2035–2054. DOI: 10.1007/BF02066241.
[
DOI link]
-
-
Plant part:
Fruit unspecified (as part-nature) (A067D)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
petroleum ether-diethyl ether OR hexane-diethyl ether-methanol
-
Substance:
isoimperatorin (RF-00003880-PAR)
-
Analytical method code:
HPLC-UV (F021A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
isoimperatorin in fruits
Composition #22: HADACEK, F., MULLER, C., WERNER, A., GREGER, H., PROKSCH, P. ANALYSIS, ISOLATION AND INSECTICIDAL ACTIVITY OF LINEAR FURANOCOUMARINS AND OTHER COUMARIN DERIVATIVES FROM PEUCEDANUM (APIACEAE, APIOIDEAE) . journal of chemical ecology, 1994, vol. 20, no. 8, p. 2035–2054. DOI: 10.1007/BF02066241.
[
DOI link]
-
-
Plant part:
Fruit unspecified (as part-nature) (A067D)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
petroleum ether-diethyl ether OR hexane-diethyl ether-methanol
-
Substance:
coumarins (RF-00004351-PAR)
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Additional substance description:
xanthotoxin
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Analytical method code:
HPLC-UV (F021A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
xanthotoxin in fruits
Endpoint study
#1: Roman, I., Rusu, M.A., Puicǎ, C., Deliu, C. Some histoenzymological (Histochemical) and biochemical changes induced by peucedanum herbal extracts upon the liver and kidney in rats. annals of the romanian society for cell biology, 2011, vol. 16, no. 2, p. 69–73. .
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Study relevance:
Human health
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Type of toxicological test:
short-term toxicity (CHD017TT)
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Tested organism:
Rat (as animal) (A0CNV)
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-
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Unit of exposure duration:
Day (G134A)
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Number of organisms dosed:
8
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Endpoint measured:
Dose not reported (CHD066EP)
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Critical effect:
NONE (TOX14A)
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Target tissue:
digestive: Liver (TT023A)
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Effect description:
a moderate increase of LDH, SDH and CyOx activities in liver and kidneys but doesn’t produce pathological modifications in the organs
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Effect or parameter linked to the endpoint:
no data (CHD002BE)
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Internal remarks:
a moderate increase of LDH, SDH and CyOx activities in liver and kidneys, but doesn’t produce pathological modifications in the organs