EFSA
ecomole
vscht
  2. Petasites hybridus (L.) "G.Gaertn., B.Mey. & Scherb." // Petasites officinalis Moench

Petasites hybridus (L.) "G.Gaertn., B.Mey. & Scherb." // Petasites officinalis Moench

Family:
Asteraceae
Approval state:
Approved
Number of articles retrieved:
471
Number of processed references:
12
Compositions
#1: senkirkine #2: senecionine #3: Pyrrolizidine alkaloids: Senecionine, Seneciphylline, Senkirkine and Tussilagine in aerial parts #4: pyrrolizidine alkaloids #5: petasin - leaves #6: pyrrolizidine alkaloids - root #7: pyrrolizidine alkaloids - leaves #8: petasin - rhizomes #9: pyrrolizidine alkaloids #10: 1-(6-hydroxy-2-isopropenyl-1- benzofuran-yl)-1-ethanone (euparin) in roots #11: isopetasin in root #12: pyrrolizidine alkaloids in root #13: 8-beta-H-eremophilanolide in root #14: S-petasin in root #15: petasin in root #16: furanopetasin- root #17: Petasitenine in rhizomes #18: Pyrrolizidine alkaloids in rhizomes #19: integerrimine #20: senecionine-N-oxide #21: senkirkine #22: senecionine #23: senkirkine - leaves #24: senecionine - leaves #25: seneciphylline and seneciphylline-N-oxide in leaves #26: senecionine-N-oxide - leaves #27: integerrimine #28: senecionine #29: senecionine - rhizomes #30: senecionine - leaves
Endpoint Studies
Genotoxicity
Composition #1: Mroczek, Tomasz., Glowniak, Kazimierz., Wlaszczyk, Anna. Simultaneous determination of N-oxides and free bases of pyrrolizidine alkaloids by cation-exchange solid-phase extraction and ion-pair high-performance liquid chromatography. journal of chromatography a, 2002, vol. 949(1-2), p. 249–262. .
Composition #2: Mroczek, Tomasz., Glowniak, Kazimierz., Wlaszczyk, Anna. Simultaneous determination of N-oxides and free bases of pyrrolizidine alkaloids by cation-exchange solid-phase extraction and ion-pair high-performance liquid chromatography. journal of chromatography a, 2002, vol. 949(1-2), p. 249–262. .
Composition #3: Sener, Bilge., Ergun, Fatma. Pyrrolizidine alkaloids from Petasites hybridus (L.) Gaertner. journal of faculty of pharmacy of gazi university, 1996, vol. 13, no. 2, p. 171–173. .
Composition #4: Pank, F., Vender, C., Van Niekerk, L., Junghanns, W., Langbehn, J., Blüthner, W.-D., Novak, J., Franz, C. Distribution of pyrrolizidine alkaloids in crossing progenies of Petasites hybridus. journal of herbs, spices and medicinal plants, 2002, vol. 9, no. 2-3, p. 39–44. DOI: 10.1300/J044v09n02_05. [DOI link]
Composition #5: Wildi, E., Langer, T., Schaffner, W., Buter, KB. Quantitative analysis of petasin and pyrrolizidine alkaloids in leaves and rhizomes of in situ grown Petasites hybridus plants . planta medica, 1998, vol. 64, no. 3, p. 264–267. DOI: 10.1055/s-2006-957422. [DOI link]
Composition #6: Wildi, E., Langer, T., Schaffner, W., Buter, KB. Quantitative analysis of petasin and pyrrolizidine alkaloids in leaves and rhizomes of in situ grown Petasites hybridus plants . planta medica, 1998, vol. 64, no. 3, p. 264–267. DOI: 10.1055/s-2006-957422. [DOI link]
Composition #7: Wildi, E., Langer, T., Schaffner, W., Buter, KB. Quantitative analysis of petasin and pyrrolizidine alkaloids in leaves and rhizomes of in situ grown Petasites hybridus plants . planta medica, 1998, vol. 64, no. 3, p. 264–267. DOI: 10.1055/s-2006-957422. [DOI link]
Composition #8: Wildi, E., Langer, T., Schaffner, W., Buter, KB. Quantitative analysis of petasin and pyrrolizidine alkaloids in leaves and rhizomes of in situ grown Petasites hybridus plants . planta medica, 1998, vol. 64, no. 3, p. 264–267. DOI: 10.1055/s-2006-957422. [DOI link]
Composition #9: Chizzola, R., Ozelsberger, B., Langer, T. Variability in chemical constituents in Petasites hybridus from Austria. biochemical systematics and ecology, 2000, vol. 28, no. 5, p. 421–432. DOI: 10.1016/S0305-1978(99)00077-0. [DOI link]
Composition #10: Rostami-Charati, Faramarz., Hossaini, Zinatossadat., Khalilzadeh, Mohammad A. Novel Isocyanide-Based Three-Component Synthesis of Substituted 9H-furo 2,3-f chromene-8,9-Dicarboxylates in Water . combinatorial chemistry & high throughput screening, 2012, vol. 15, no. 5, p. 433–437. .
Composition #11: Avula, Bharathi., Wang, Yan-Hong., Wang, Mei., Smillie, Troy J., Khan, Ikhlas A. Simultaneous determination of sesquiterpenes and pyrrolizidine alkaloids from the rhizomes of Petasites hybridus (L.) GM et Sch and dietary supplements using UPLC-UV and HPLC-TOF-MS methods . journal of pharmaceutical and biomedical analysis, 2012, vol. 70, p. 53–63. DOI: 10.1016/j.jpba.2012.05.021. [DOI link]
Composition #12: Avula, Bharathi., Wang, Yan-Hong., Wang, Mei., Smillie, Troy J., Khan, Ikhlas A. Simultaneous determination of sesquiterpenes and pyrrolizidine alkaloids from the rhizomes of Petasites hybridus (L.) GM et Sch and dietary supplements using UPLC-UV and HPLC-TOF-MS methods . journal of pharmaceutical and biomedical analysis, 2012, vol. 70, p. 53–63. DOI: 10.1016/j.jpba.2012.05.021. [DOI link]
Composition #13: Avula, Bharathi., Wang, Yan-Hong., Wang, Mei., Smillie, Troy J., Khan, Ikhlas A. Simultaneous determination of sesquiterpenes and pyrrolizidine alkaloids from the rhizomes of Petasites hybridus (L.) GM et Sch and dietary supplements using UPLC-UV and HPLC-TOF-MS methods . journal of pharmaceutical and biomedical analysis, 2012, vol. 70, p. 53–63. DOI: 10.1016/j.jpba.2012.05.021. [DOI link]
Composition #14: Avula, Bharathi., Wang, Yan-Hong., Wang, Mei., Smillie, Troy J., Khan, Ikhlas A. Simultaneous determination of sesquiterpenes and pyrrolizidine alkaloids from the rhizomes of Petasites hybridus (L.) GM et Sch and dietary supplements using UPLC-UV and HPLC-TOF-MS methods . journal of pharmaceutical and biomedical analysis, 2012, vol. 70, p. 53–63. DOI: 10.1016/j.jpba.2012.05.021. [DOI link]
Composition #15: Avula, Bharathi., Wang, Yan-Hong., Wang, Mei., Smillie, Troy J., Khan, Ikhlas A. Simultaneous determination of sesquiterpenes and pyrrolizidine alkaloids from the rhizomes of Petasites hybridus (L.) GM et Sch and dietary supplements using UPLC-UV and HPLC-TOF-MS methods . journal of pharmaceutical and biomedical analysis, 2012, vol. 70, p. 53–63. DOI: 10.1016/j.jpba.2012.05.021. [DOI link]
Composition #16: Avula, Bharathi., Wang, Yan-Hong., Wang, Mei., Smillie, Troy J., Khan, Ikhlas A. Simultaneous determination of sesquiterpenes and pyrrolizidine alkaloids from the rhizomes of Petasites hybridus (L.) GM et Sch and dietary supplements using UPLC-UV and HPLC-TOF-MS methods . journal of pharmaceutical and biomedical analysis, 2012, vol. 70, p. 53–63. DOI: 10.1016/j.jpba.2012.05.021. [DOI link]
Composition #17: Aydin, Ahmet Alper., Letzel, Thomas. Simultaneous investigation of sesquiterpenes, pyrrolizidine alkaloids and N-oxides in Butterbur (Petasites hybridus) with an offline 2D-combination of HPLC-UV and LC-MMI-ToF-MS . journal of pharmaceutical and biomedical analysis, 2013, vol. 85, p. 74–82. DOI: 10.1016/j.jpba.2013.06.022. [DOI link]
Composition #18: Aydin, Ahmet Alper., Letzel, Thomas. Simultaneous investigation of sesquiterpenes, pyrrolizidine alkaloids and N-oxides in Butterbur (Petasites hybridus) with an offline 2D-combination of HPLC-UV and LC-MMI-ToF-MS . journal of pharmaceutical and biomedical analysis, 2013, vol. 85, p. 74–82. DOI: 10.1016/j.jpba.2013.06.022. [DOI link]
Composition #19: Avula, Bharathi., Sagi, Satyanarayanaraju., Wang, Yan-Hong., Zweigenbaum, Jerry., Wang, Mei., Khan, Ikhlas A. Characterization and screening of pyrrolizidine alkaloids and N-oxides from botanicals and dietary supplements using UHPLC-high resolution mass spectrometry . food chemistry, 2015, vol. 178, p. 136–148. DOI: 10.1016/j.foodchem.2015.01.053. [DOI link]
Composition #20: Avula, Bharathi., Sagi, Satyanarayanaraju., Wang, Yan-Hong., Zweigenbaum, Jerry., Wang, Mei., Khan, Ikhlas A. Characterization and screening of pyrrolizidine alkaloids and N-oxides from botanicals and dietary supplements using UHPLC-high resolution mass spectrometry . food chemistry, 2015, vol. 178, p. 136–148. DOI: 10.1016/j.foodchem.2015.01.053. [DOI link]
Composition #21: Avula, Bharathi., Sagi, Satyanarayanaraju., Wang, Yan-Hong., Zweigenbaum, Jerry., Wang, Mei., Khan, Ikhlas A. Characterization and screening of pyrrolizidine alkaloids and N-oxides from botanicals and dietary supplements using UHPLC-high resolution mass spectrometry . food chemistry, 2015, vol. 178, p. 136–148. DOI: 10.1016/j.foodchem.2015.01.053. [DOI link]
Composition #22: Avula, Bharathi., Sagi, Satyanarayanaraju., Wang, Yan-Hong., Zweigenbaum, Jerry., Wang, Mei., Khan, Ikhlas A. Characterization and screening of pyrrolizidine alkaloids and N-oxides from botanicals and dietary supplements using UHPLC-high resolution mass spectrometry . food chemistry, 2015, vol. 178, p. 136–148. DOI: 10.1016/j.foodchem.2015.01.053. [DOI link]
Composition #23: Schenk, Alexander., Siewert, Beate., Toff, Stephan., Drewe, Juergen. UPLC TOF MS for sensitive quantification of naturally occurring pyrrolizidine alkaloids in Petasites hybridus extract (Ze 339) . journal of chromatography b-analytical technologies in the biomedical and life sciences, 2015, vol. 997, p. 23–29. DOI: 10.1016/j.jchromb.2015.05.027. [DOI link]
Composition #24: Schenk, Alexander., Siewert, Beate., Toff, Stephan., Drewe, Juergen. UPLC TOF MS for sensitive quantification of naturally occurring pyrrolizidine alkaloids in Petasites hybridus extract (Ze 339) . journal of chromatography b-analytical technologies in the biomedical and life sciences, 2015, vol. 997, p. 23–29. DOI: 10.1016/j.jchromb.2015.05.027. [DOI link]
Composition #25: Schenk, Alexander., Siewert, Beate., Toff, Stephan., Drewe, Juergen. UPLC TOF MS for sensitive quantification of naturally occurring pyrrolizidine alkaloids in Petasites hybridus extract (Ze 339) . journal of chromatography b-analytical technologies in the biomedical and life sciences, 2015, vol. 997, p. 23–29. DOI: 10.1016/j.jchromb.2015.05.027. [DOI link]
Composition #26: Schenk, Alexander., Siewert, Beate., Toff, Stephan., Drewe, Juergen. UPLC TOF MS for sensitive quantification of naturally occurring pyrrolizidine alkaloids in Petasites hybridus extract (Ze 339) . journal of chromatography b-analytical technologies in the biomedical and life sciences, 2015, vol. 997, p. 23–29. DOI: 10.1016/j.jchromb.2015.05.027. [DOI link]
Composition #27: CHIZZOLA, R. RAPID SAMPLE PREPARATION TECHNIQUE FOR THE DETERMINATION OF PYRROLIZIDINE ALKALOIDS IN PLANT-EXTRACTS . journal of chromatography a, 1994, vol. 668, no. 2, p. 427–433. DOI: 10.1016/0021-9673(94)80135-5. [DOI link]
Composition #28: CHIZZOLA, R. RAPID SAMPLE PREPARATION TECHNIQUE FOR THE DETERMINATION OF PYRROLIZIDINE ALKALOIDS IN PLANT-EXTRACTS . journal of chromatography a, 1994, vol. 668, no. 2, p. 427–433. DOI: 10.1016/0021-9673(94)80135-5. [DOI link]
Composition #29: Langer, T., Mostl, E., Chizzola, R., Gutleb, R. A competitive enzyme immunoassay for the pyrrolizidine alkaloids of the senecionine type . planta medica, 1996, vol. 62, no. 3, p. 267–271. DOI: 10.1055/s-2006-957875. [DOI link]
Composition #30: Langer, T., Mostl, E., Chizzola, R., Gutleb, R. A competitive enzyme immunoassay for the pyrrolizidine alkaloids of the senecionine type . planta medica, 1996, vol. 62, no. 3, p. 267–271. DOI: 10.1055/s-2006-957875. [DOI link]