EFSA Compendium of Botanicals

Draft - work in progress

Ocotea odorifera (Vell.) Rohwer // Ocotea pretiosa Mez

Family:: Lauraceae
Approval state:: Approved
Number of articles retrieved:: 91
Number of processed references:: 4

Compositions

#1: Fraxetin in seeds (integument) #2: Methyleugenol in essential oil from leaves #3: Safrole in essential oil from leaves #4: camphor in essential oil from leaves #5: Eucalyptol (syn. of 1,8-cineole) in essential oil from leaves #6: Eugenol in essential oil from leaves #7: Globulol in essential oil from leaves #8: beta-Eudesmol in essential oil from leaves #9: safrole in essential oil from leaves #10: Ellagitannin (Tellimagrandin II) in leaves.

Endpoint Studies

Genotoxicity

Composition #1: Marques, Marcia O. M., Yoshida, Massayoshi. Structure of propacin. quimica nova, 1990, vol. 13, no. 4, p. 245–6. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol
Substance:

Fraxetin (RF-00010996-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Fraxetin in seeds (integument)

Composition #2: Lima, Rafaela Karin., Cardoso, Maria das Gracas., Moraes, Jair Campos., Carvalho, Stephan Malfitano., Melo, Bruno Almeida., Vieira, Sara Silveira. Chemical composition and toxicity of essential oils to the green-aphid Schizaphis graminum (Rondani, 1852) . arquivos do instituto biologico sao paulo, 2014, vol. 81, no. 1, p. 22–29. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

methyleugenol (RF-00003931-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

81.2
Internal remarks:

Methyleugenol in essential oil from leaves

Composition #3: Lima, Rafaela Karin., Cardoso, Maria das Gracas., Moraes, Jair Campos., Carvalho, Stephan Malfitano., Melo, Bruno Almeida., Vieira, Sara Silveira. Chemical composition and toxicity of essential oils to the green-aphid Schizaphis graminum (Rondani, 1852) . arquivos do instituto biologico sao paulo, 2014, vol. 81, no. 1, p. 22–29. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

Safrole (RF-00003651-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

10.6
Internal remarks:

Safrole in essential oil from leaves

Composition #4: Alcoba, Ana E T., Melo, Daiana C de., de Andrade, Priscila M., Dias, Herbert J., Pagotti, Mariana C., Magalhaes, Lizandra G., Junior, Walnir G F., Crotti, Antonio E M., Miranda, Mayker L D. Chemical composition and in vitro antileishmanial and cytotoxic activities of the essential oils of Ocotea dispersa (Nees) Mez and Ocotea odorifera (Vell) Rohwer (Lauraceae). . natural product research, 2017, p. 1–4. DOI: 10.1080/14786419.2017.1385007. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

6.5
Internal remarks:

camphor in essential oil from leaves

Composition #5: Alcoba, Ana E T., Melo, Daiana C de., de Andrade, Priscila M., Dias, Herbert J., Pagotti, Mariana C., Magalhaes, Lizandra G., Junior, Walnir G F., Crotti, Antonio E M., Miranda, Mayker L D. Chemical composition and in vitro antileishmanial and cytotoxic activities of the essential oils of Ocotea dispersa (Nees) Mez and Ocotea odorifera (Vell) Rohwer (Lauraceae). . natural product research, 2017, p. 1–4. DOI: 10.1080/14786419.2017.1385007. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

1,8-cineole (RF-00003470-PAR)
Additional substance description:

Eucalyptol (syn. of 1,8-cineole)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.7
Internal remarks:

Eucalyptol (syn. of 1,8-cineole) in essential oil from leaves

Composition #6: Alcoba, Ana E T., Melo, Daiana C de., de Andrade, Priscila M., Dias, Herbert J., Pagotti, Mariana C., Magalhaes, Lizandra G., Junior, Walnir G F., Crotti, Antonio E M., Miranda, Mayker L D. Chemical composition and in vitro antileishmanial and cytotoxic activities of the essential oils of Ocotea dispersa (Nees) Mez and Ocotea odorifera (Vell) Rohwer (Lauraceae). . natural product research, 2017, p. 1–4. DOI: 10.1080/14786419.2017.1385007. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Eugenol (RF-00003807-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.8
Internal remarks:

Eugenol in essential oil from leaves

Composition #7: Alcoba, Ana E T., Melo, Daiana C de., de Andrade, Priscila M., Dias, Herbert J., Pagotti, Mariana C., Magalhaes, Lizandra G., Junior, Walnir G F., Crotti, Antonio E M., Miranda, Mayker L D. Chemical composition and in vitro antileishmanial and cytotoxic activities of the essential oils of Ocotea dispersa (Nees) Mez and Ocotea odorifera (Vell) Rohwer (Lauraceae). . natural product research, 2017, p. 1–4. DOI: 10.1080/14786419.2017.1385007. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

(-)-globulol (RF-00003756-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.4
Internal remarks:

Globulol in essential oil from leaves

Composition #8: Alcoba, Ana E T., Melo, Daiana C de., de Andrade, Priscila M., Dias, Herbert J., Pagotti, Mariana C., Magalhaes, Lizandra G., Junior, Walnir G F., Crotti, Antonio E M., Miranda, Mayker L D. Chemical composition and in vitro antileishmanial and cytotoxic activities of the essential oils of Ocotea dispersa (Nees) Mez and Ocotea odorifera (Vell) Rohwer (Lauraceae). . natural product research, 2017, p. 1–4. DOI: 10.1080/14786419.2017.1385007. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

beta-Eudesmol (RF-00010708-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.7
Internal remarks:

beta-Eudesmol in essential oil from leaves

Composition #9: Alcoba, Ana E T., Melo, Daiana C de., de Andrade, Priscila M., Dias, Herbert J., Pagotti, Mariana C., Magalhaes, Lizandra G., Junior, Walnir G F., Crotti, Antonio E M., Miranda, Mayker L D. Chemical composition and in vitro antileishmanial and cytotoxic activities of the essential oils of Ocotea dispersa (Nees) Mez and Ocotea odorifera (Vell) Rohwer (Lauraceae). . natural product research, 2017, p. 1–4. DOI: 10.1080/14786419.2017.1385007. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Safrole (RF-00003651-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

36.3
Internal remarks:

safrole in essential oil from leaves

Composition #10: Yamaguchi, Mirian Ueda., Garcia, Francielle Pelegrin., Garcia Cortez, Diogenes Aparicio., Ueda-Nakamura, Tania., Dias Filho, Benedito Prado., Nakamura, Celso Vataru. Antifungal effects of Ellagitannin isolated from leaves of Ocotea odorifera (Lauraceae) . antonie van leeuwenhoek international journal of general and molecular microbiology, 2011, vol. 99, no. 3, p. 507–514. DOI: 10.1007/s10482-010-9516-3. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Ellagitannins (hydrolysable tannins) Ellagitannins (hydrolysable tannins) (RF-00004379-PAR)
Additional substance description:

Tellimagrandin II
Analytical method code:

Chromatographic tests (F015A)
Analytical method - additional description:

NMR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Ellagitannin (Tellimagrandin II) in leaves.