EFSA Compendium of Botanicals

Draft - work in progress

Ocimum campechianum Mill. // Ocimum micranthum Willd.

Family:: Lamiaceae
Approval state:: Approved
Number of articles retrieved:: 85
Number of processed references:: 8

Compositions

Endpoint Studies

Genotoxicity

Composition #1: Vina, Amparo., Murillo, Elizabeth. Essential oil composition from twelve varieties of basil (Ocimum spp) grown in Colombia. journal of the brazilian chemical society, 2003, vol. 14, no. 5, p. 744–749. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydrodistillation
Substance:

Estragole (RF-00003806-PAR)
Additional substance description:

"methyl chavicol"
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

12.33
Internal remarks:

Estragol (methyl chavicol) in aerial parts

Composition #2: Silva, M.G.D.V., Craveiro, A.A., Machado, M.I.L., Alencar, J.W., Matos, F.J.A., Aurélio, F.K.F. Essential oils from leaves and inflorescences of ocimum micranthum willd. from northeastern Brazil. journal of essential oil research, 1998, vol. 10, no. 1, p. 77–78. DOI: 10.1080/10412905.1998.9700843. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Microwave distillation
Substance:

elemicin (RF-00003787-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

Also 13C-NMR
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

32.9
Internal remarks:

Elemicin in essential oil of flowers

Composition #3: Silva, M.G.D.V., Craveiro, A.A., Machado, M.I.L., Alencar, J.W., Matos, F.J.A., Aurélio, F.K.F. Essential oils from leaves and inflorescences of ocimum micranthum willd. from northeastern Brazil. journal of essential oil research, 1998, vol. 10, no. 1, p. 77–78. DOI: 10.1080/10412905.1998.9700843. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Steam distillation
Substance:

Naphthalene derivatives (RF-00010833-PAR)
Additional substance description:

Eremophilene
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

Also 13C-NMR
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

5.8
Internal remarks:

Eremophilene (naphthalene derivative) in essential oil of leaves

Composition #4: Silva, M.G.D.V., Craveiro, A.A., Machado, M.I.L., Alencar, J.W., Matos, F.J.A., Aurélio, F.K.F. Essential oils from leaves and inflorescences of ocimum micranthum willd. from northeastern Brazil. journal of essential oil research, 1998, vol. 10, no. 1, p. 77–78. DOI: 10.1080/10412905.1998.9700843. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Microwave distillation
Substance:

Eugenol (RF-00003807-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

Also 13C-NMR
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

14.0
Internal remarks:

Eugenol in essential oil of flowers

Composition #5: Silva, M.G.D.V., Craveiro, A.A., Machado, M.I.L., Alencar, J.W., Matos, F.J.A., Aurélio, F.K.F. Essential oils from leaves and inflorescences of ocimum micranthum willd. from northeastern Brazil. journal of essential oil research, 1998, vol. 10, no. 1, p. 77–78. DOI: 10.1080/10412905.1998.9700843. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Microwave distillation
Substance:

methyleugenol (RF-00003931-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

Also 13C-NMR
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

6.2
Internal remarks:

Methyl eugenol in essential oil of flowers

Composition #6: Coe, F.G., Parikh, D.M., Johnson, C.A. Alkaloid presence and brine shrimp (Artemia salina) bioassay of medicinal species of eastern Nicaragua. pharmaceutical biology, 2010, vol. 48, no. 4, p. 439–445. DOI: 10.3109/13880200903168015. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

0.5-1 mL of 2:1 CHCl3-MeOH
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids in leaves

Composition #7: Silva, MGDV., Matos, FJA., Machado, MIL., Silva, FDO. Essential oil composition of the leaves of Ocimum micranthum Willd.. journal of essential oil research, 2004, vol. 16, no. 3, p. 189–190. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydrodistillation, then extraction with Ch2Cl2
Substance:

beta-selinene (RF-00011306-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.6-2.8
Internal remarks:

beta-Selinene in leaf oil

Composition #8: Silva, MGDV., Matos, FJA., Machado, MIL., Silva, FDO. Essential oil composition of the leaves of Ocimum micranthum Willd.. journal of essential oil research, 2004, vol. 16, no. 3, p. 189–190. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydrodistillation, then extraction with Ch2Cl2
Substance:

elemicin (RF-00003787-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

21.6
Internal remarks:

Elemicin in leaf oil

Composition #9: Silva, MGDV., Matos, FJA., Machado, MIL., Silva, FDO. Essential oil composition of the leaves of Ocimum micranthum Willd.. journal of essential oil research, 2004, vol. 16, no. 3, p. 189–190. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydrodistillation, then extraction with Ch2Cl2
Substance:

Eugenol (RF-00003807-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

84.0-97.0
Internal remarks:

Eugenol in leaf oil

Composition #10: Rosas, JF., Zoghbi, MDB., Andrade, EHA., van den Berg, ME. Chemical composition of a methyl-(E)-cinnamate Ocimum micranthum Willd. from the Amazon . flavour and fragrance journal, 2005, vol. 20, no. 2, p. 161–163. DOI: 10.1002/ffj.1374. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydrodistillation
Substance:

Carvone (RF-0538-001-PPP)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

16.1
Internal remarks:

Carvone in essential oil of aerial parts

Composition #11: Rosas, JF., Zoghbi, MDB., Andrade, EHA., van den Berg, ME. Chemical composition of a methyl-(E)-cinnamate Ocimum micranthum Willd. from the Amazon . flavour and fragrance journal, 2005, vol. 20, no. 2, p. 161–163. DOI: 10.1002/ffj.1374. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydrodistillation
Substance:

fenchone (RF-00003814-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.1
Internal remarks:

Fenchone in essential oil of aerial parts

Composition #12: Zoghbi, Maria das Gracas B., Oliveira, Jorge., Andrade, Eloisa Helena A., Trigo, Jose Roberto., Fonseca, Roberta Carolina M., Rocha, Antonio Elielson S. Variation in volatiles of Ocimum campechianum Mill. and Ocimum gratissimum L. cultivated in the North of Brazil . journal of essential oil bearing plants, 2007, vol. 10, no. 3, p. 229–240. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydrodistillation
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-FID-MS (F607A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.9-19.7
Internal remarks:

1,8-cineole in aerial parts

Composition #13: Zoghbi, Maria das Gracas B., Oliveira, Jorge., Andrade, Eloisa Helena A., Trigo, Jose Roberto., Fonseca, Roberta Carolina M., Rocha, Antonio Elielson S. Variation in volatiles of Ocimum campechianum Mill. and Ocimum gratissimum L. cultivated in the North of Brazil . journal of essential oil bearing plants, 2007, vol. 10, no. 3, p. 229–240. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydrodistillation
Substance:

elemicin (RF-00003787-PAR)
Analytical method code:

GC-FID-MS (F607A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=65.9
Internal remarks:

Elemicin in aerial parts

Composition #14: Zoghbi, Maria das Gracas B., Oliveira, Jorge., Andrade, Eloisa Helena A., Trigo, Jose Roberto., Fonseca, Roberta Carolina M., Rocha, Antonio Elielson S. Variation in volatiles of Ocimum campechianum Mill. and Ocimum gratissimum L. cultivated in the North of Brazil . journal of essential oil bearing plants, 2007, vol. 10, no. 3, p. 229–240. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydrodistillation
Substance:

beta-selinene (RF-00011306-PAR)
Analytical method code:

GC-FID-MS (F607A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.5-7.0
Internal remarks:

beta-Selinene in aerial parts

Composition #15: Zoghbi, Maria das Gracas B., Oliveira, Jorge., Andrade, Eloisa Helena A., Trigo, Jose Roberto., Fonseca, Roberta Carolina M., Rocha, Antonio Elielson S. Variation in volatiles of Ocimum campechianum Mill. and Ocimum gratissimum L. cultivated in the North of Brazil . journal of essential oil bearing plants, 2007, vol. 10, no. 3, p. 229–240. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydrodistillation
Substance:

methyleugenol (RF-00003931-PAR)
Analytical method code:

GC-FID-MS (F607A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=69.5
Internal remarks:

Methyl Eugenol in aerial parts

Composition #16: Zoghbi, Maria das Gracas B., Oliveira, Jorge., Andrade, Eloisa Helena A., Trigo, Jose Roberto., Fonseca, Roberta Carolina M., Rocha, Antonio Elielson S. Variation in volatiles of Ocimum campechianum Mill. and Ocimum gratissimum L. cultivated in the North of Brazil . journal of essential oil bearing plants, 2007, vol. 10, no. 3, p. 229–240. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydrodistillation
Substance:

alpha-Selinene (RF-00010780-PAR)
Analytical method code:

GC-FID-MS (F607A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.2-4.0
Internal remarks:

alpha-Selinene in aerial parts

Composition #17: Zoghbi, Maria das Gracas B., Oliveira, Jorge., Andrade, Eloisa Helena A., Trigo, Jose Roberto., Fonseca, Roberta Carolina M., Rocha, Antonio Elielson S. Variation in volatiles of Ocimum campechianum Mill. and Ocimum gratissimum L. cultivated in the North of Brazil . journal of essential oil bearing plants, 2007, vol. 10, no. 3, p. 229–240. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydrodistillation
Substance:

Eugenol (RF-00003807-PAR)
Analytical method code:

GC-FID-MS (F607A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=60.6
Internal remarks:

Eugenol in aerial parts

Composition #18: Pino Benitez, Nayive., Melendez Leon, Erika M., Stashenko, Elena E. Eugenol and Methyl Eugenol Chemotypes of Essential Oil of Species Ocimum gratissimum L. and Ocimum campechianum Mill. from Colombia . journal of chromatographic science, 2009, vol. 47, no. 9, p. 800–803. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Microwave-assisted hydrodistillation
Substance:

sesquiterpene lactones type eudesmanolide sesquiterpene lactones type eudesmanolide (RF-00004395-PAR)
Additional substance description:

"alpha-Guaiene" and "alpha-bulnesene"
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

5.6-7.1
Internal remarks:

alpha-Guaiene and alpha-bulnesene (eudesmanaloid sesquiterpenes) in essential oil of leaves

Composition #19: Mota, M. S. C. S., Silva, R. S., Silva, G. A., Picanco, M. C., Mesquita, A. L. M., Pereira, R. C. A. Potential of allelochemicals from basil (Ocimum micranthum Willd) to control whitefly (Aleurodicus cocois (Curtis, 1846)) in cashew nut crop (Anacardium occidentale L.) . allelopathy journal, 2017, vol. 40, no. 2, p. 197–210. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydrodistillation
Substance:

beta-selinene (RF-00011306-PAR)
Analytical method code:

GC-ITMS (F045A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.20
Internal remarks:

beta-Selinene in essential oil of leaves

Composition #20: Mota, M. S. C. S., Silva, R. S., Silva, G. A., Picanco, M. C., Mesquita, A. L. M., Pereira, R. C. A. Potential of allelochemicals from basil (Ocimum micranthum Willd) to control whitefly (Aleurodicus cocois (Curtis, 1846)) in cashew nut crop (Anacardium occidentale L.) . allelopathy journal, 2017, vol. 40, no. 2, p. 197–210. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydrodistillation
Substance:

elemicin (RF-00003787-PAR)
Analytical method code:

GC-ITMS (F045A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

16.09
Internal remarks:

Elemicin in essential oil of leaves

Composition #21: Mota, M. S. C. S., Silva, R. S., Silva, G. A., Picanco, M. C., Mesquita, A. L. M., Pereira, R. C. A. Potential of allelochemicals from basil (Ocimum micranthum Willd) to control whitefly (Aleurodicus cocois (Curtis, 1846)) in cashew nut crop (Anacardium occidentale L.) . allelopathy journal, 2017, vol. 40, no. 2, p. 197–210. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydrodistillation
Substance:

Eugenol (RF-00003807-PAR)
Analytical method code:

GC-ITMS (F045A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

41.05
Internal remarks:

Eugenol in essential oil of leaves

Composition #22: Mota, M. S. C. S., Silva, R. S., Silva, G. A., Picanco, M. C., Mesquita, A. L. M., Pereira, R. C. A. Potential of allelochemicals from basil (Ocimum micranthum Willd) to control whitefly (Aleurodicus cocois (Curtis, 1846)) in cashew nut crop (Anacardium occidentale L.) . allelopathy journal, 2017, vol. 40, no. 2, p. 197–210. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydrodistillation
Substance:

methyleugenol (RF-00003931-PAR)
Analytical method code:

GC-ITMS (F045A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.31
Internal remarks:

Methyl eugenol in essential oil of leaves