Draft - work in progress
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- Basil // Ocimum basilicum L.
Basil // Ocimum basilicum L.
- Family:
- Lamiaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 6330
- Number of processed references:
- 7
Composition #1: Tateo, F., Santamaria, L., Bianchi, L., Bianchi, A. Basil oil and tarragon oil: Composition and genotoxicity evaluation. journal of essential oil research, 1989, vol. 1, no. 3, p. 111–118. DOI: 10.1080/10412905.1989.9697766.
[
DOI link]
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Additional extraction description:
hydrodistillation
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Substance:
Eugenol (RF-00003807-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
2.5
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Internal remarks:
eugenol in essential oil
Composition #2: Tateo, F., Santamaria, L., Bianchi, L., Bianchi, A. Basil oil and tarragon oil: Composition and genotoxicity evaluation. journal of essential oil research, 1989, vol. 1, no. 3, p. 111–118. DOI: 10.1080/10412905.1989.9697766.
[
DOI link]
-
-
Plant part:
Aerial part of plants (as part-nature) (A166F)
-
Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Additional extraction description:
hydrodistillation
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Substance:
Estragole (RF-00003806-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
8.1 - 16.5
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Internal remarks:
estragole in essential oil
Composition #3: Tateo, F., Santamaria, L., Bianchi, L., Bianchi, A. Basil oil and tarragon oil: Composition and genotoxicity evaluation. journal of essential oil research, 1989, vol. 1, no. 3, p. 111–118. DOI: 10.1080/10412905.1989.9697766.
[
DOI link]
-
-
Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Additional extraction description:
hydrodistillation
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Substance:
methyleugenol (RF-00003931-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
0.5 - 1.6
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Internal remarks:
methyleugenol in essential oil
Composition #4: Siano, F., Ghizzoni, C., Gionfriddo, F., Colombo, E., Servillo, L., Castaldo, D. Determination of estragole, safrole and eugenol methyl ether in food products. food chemistry, 2003, vol. 81, no. 3, p. 469–475. DOI: 10.1016/S0308-8146(03)00004-9.
[
DOI link]
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Additional extraction description:
unspecified
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Substance:
Eugenol (RF-00003807-PAR)
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Additional substance description:
Eugenol methyl ether
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Analytical method code:
GC-MS (F046A)
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Result unit:
Milligram/kilogram (G061A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
0.49 - 0.75
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Internal remarks:
Eugenol methyl ether in aerial parts
Composition #5: Siano, F., Ghizzoni, C., Gionfriddo, F., Colombo, E., Servillo, L., Castaldo, D. Determination of estragole, safrole and eugenol methyl ether in food products. food chemistry, 2003, vol. 81, no. 3, p. 469–475. DOI: 10.1016/S0308-8146(03)00004-9.
[
DOI link]
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Additional extraction description:
unspecified
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Substance:
Estragole (RF-00003806-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Milligram/kilogram (G061A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
10.21 - 16.05
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Internal remarks:
estragol in aerial parts
Composition #6: Stajkovic, Olivera., Beric-Bjedov, Tanja., Mitic-Culafic, Dragana., Stankovic, Slavisa., Vukovic-Gacic, Branka., Simic, Draga., Knezevic-Vukcevic, Jelena. Antimutagenic properties of basil (Ocimum basilicum L.) in Salmonella typhimurium TA100. food technology and biotechnology, 2007, vol. 45, no. 2, p. 213–217. .
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-
Plant part:
Aerial part of plants (as part-nature) (A166F)
-
Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
-
Additional extraction description:
hydrodistillation
-
Substance:
Estragole (RF-00003806-PAR)
-
Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
-
Value (concentration, content):
2.4
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Internal remarks:
estragol in essential oil
Composition #7: Stajkovic, Olivera., Beric-Bjedov, Tanja., Mitic-Culafic, Dragana., Stankovic, Slavisa., Vukovic-Gacic, Branka., Simic, Draga., Knezevic-Vukcevic, Jelena. Antimutagenic properties of basil (Ocimum basilicum L.) in Salmonella typhimurium TA100. food technology and biotechnology, 2007, vol. 45, no. 2, p. 213–217. .
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-
Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Additional extraction description:
hydrodistillation
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Substance:
alpha-Selinene (RF-00010780-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
1.67
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Internal remarks:
alpha-selinene in essential oil
Composition #8: Stajkovic, Olivera., Beric-Bjedov, Tanja., Mitic-Culafic, Dragana., Stankovic, Slavisa., Vukovic-Gacic, Branka., Simic, Draga., Knezevic-Vukcevic, Jelena. Antimutagenic properties of basil (Ocimum basilicum L.) in Salmonella typhimurium TA100. food technology and biotechnology, 2007, vol. 45, no. 2, p. 213–217. .
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-
Plant part:
Aerial part of plants (as part-nature) (A166F)
-
Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
-
Additional extraction description:
hydrodistillation
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Substance:
beta-selinene (RF-00011306-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
1.04
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Internal remarks:
beta-selinene in essential oil
Composition #9: Stajkovic, Olivera., Beric-Bjedov, Tanja., Mitic-Culafic, Dragana., Stankovic, Slavisa., Vukovic-Gacic, Branka., Simic, Draga., Knezevic-Vukcevic, Jelena. Antimutagenic properties of basil (Ocimum basilicum L.) in Salmonella typhimurium TA100. food technology and biotechnology, 2007, vol. 45, no. 2, p. 213–217. .
-
-
Plant part:
Aerial part of plants (as part-nature) (A166F)
-
Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
-
Additional extraction description:
hydrodistillation
-
Substance:
Eugenol (RF-00003807-PAR)
-
Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
-
Value (concentration, content):
1.4
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Internal remarks:
eugenol in essential oil
Composition #10: Eliopoulos, P. A., Hassiotis, C. N., Andreadis, S. S., Porichi, A. -E. E. Fumigant Toxicity of Essential Oils from Basil and Spearmint Against Two Major Pyralid Pests of Stored Products. journal of economic entomology, 2015, vol. 108, no. 2, p. 805–810. DOI: 10.1093/jee/tov029.
[
DOI link]
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Substance:
1,8-cineole (RF-00003470-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
16.7
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Internal remarks:
1,8-cineole in essential oil
Composition #11: Eliopoulos, P. A., Hassiotis, C. N., Andreadis, S. S., Porichi, A. -E. E. Fumigant Toxicity of Essential Oils from Basil and Spearmint Against Two Major Pyralid Pests of Stored Products. journal of economic entomology, 2015, vol. 108, no. 2, p. 805–810. DOI: 10.1093/jee/tov029.
[
DOI link]
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Substance:
Camphor (RF-00003986-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
1.2
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Internal remarks:
Camphor in essential oil
Composition #12: Eliopoulos, P. A., Hassiotis, C. N., Andreadis, S. S., Porichi, A. -E. E. Fumigant Toxicity of Essential Oils from Basil and Spearmint Against Two Major Pyralid Pests of Stored Products. journal of economic entomology, 2015, vol. 108, no. 2, p. 805–810. DOI: 10.1093/jee/tov029.
[
DOI link]
-
-
Plant part:
Aerial part of plants (as part-nature) (A166F)
-
Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
-
Substance:
Eugenol (RF-00003807-PAR)
-
Analytical method code:
GC-MS (F046A)
-
Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
-
Value (concentration, content):
10.3
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Internal remarks:
Eugenol in essential oil
Composition #13: Nascimento de Araujo, Alice Maria., D'Antonino Faroni, Leda Rita., de Oliveira, Jose Vargas., do Amaral Ferraz Navarro, Daniela Maria., Rafael e Silva Barbosa, Douglas., Breda, Mariana Oliveira., de Franca, Solange Maria. Lethal and sublethal responses of Sitophilus zeamais populations to essential oils. journal of pest science, 2017, vol. 90, no. 2, p. 589–600. DOI: 10.1007/s10340-016-0822-z.
[
DOI link]
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-
Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
-
Additional extraction description:
hydrodistillation
-
Substance:
1,8-cineole (RF-00003470-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
3.74
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Internal remarks:
1,8-cineole in essential oil
Endpoint study
#1: Parra, AL., Yhebra, RS., Sardinas, IG., Buela, LI. Comparative study of the assay of Artemia salina L. and the estimate of the medium lethal dose (LD50 value) in mice, to determine oral acute toxicity of plant extracts. phytomedicine, 2001, vol. 8, no. 5, p. 395–400. .
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Study relevance:
Human health
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Preparation/Extraction method:
Essential oil (as part-nature) (A166Q)
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Type of toxicological test:
acute toxicity (CHD016TT)
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Tested organism:
House mouse (as animal) (A0CNT)
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-
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Unit of exposure duration:
Hour (G099A)
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Control groups used:
no data
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Endpoint measured:
Dose producing lethality in 50% of experimental organisms (CHD024EP)
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Concentration unit:
Milligram/kilogram (G061A)
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Effect concentration:
956.50
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Critical effect:
Other toxicities (TOX19A)
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Effect description:
LD50 values obtained following the “in vivo” test in mice (956.5 milligram/ kg). Such values were estimated using the mortality results obtained 24 hours after oral administration.
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Effect or parameter linked to the endpoint:
mortality (CHD010BE)
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Internal remarks:
Lethal dose in mice
Endpoint study
#2: Venancio, Antonio Medeiros., Casimiro Onofre, Alexandre Sherlley., Lira, Amintas Figueiredo., Alves, Pericles Barreto., Blank, Arie Fitzgerald., Antoniolli, Angelo Roberto., Marchioro, Murilo., Estevam, Charles dos Santos., de Araujo, Brancilene Santos. Chemical Composition, Acute Toxicity, and Antinociceptive Activity of the Essential Oil of a Plant Breeding Cultivar of Basil (Ocimum basilicum L.). planta medica, 2011, vol. 77, no. 8, p. 825–829. DOI: 10.1055/s-0030-1250607.
[
DOI link]
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Study relevance:
Human health
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Plant part:
Leaves (as part-nature) (A0EKT)
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Preparation/Extraction method:
Essential oil (as part-nature) (A166Q)
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Additional plant/substance description:
hydrodistillation
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Type of toxicological test:
acute toxicity (CHD016TT)
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Tested organism:
House mouse (as animal) (A0CNT)
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Route of exposure:
ORAL: UNSPECIFIED (OECD2234PL)
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Unit of exposure duration:
Hour (G099A)
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Endpoint measured:
Lethal dose rate in 50% of experimental organisms (CHD029EP)
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Concentration unit:
Milligrams per kilogram body weight (G225A)
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Effect concentration:
532
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Critical effect:
Other toxicities (TOX19A)
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Effect description:
Lethal dose to cause 50% death (LD50) was calculated from a dose-response curve (100–5000mg/ kg body wt.; n = 6) as 532 mg/kg body wt.
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Effect or parameter linked to the endpoint:
mortality (CHD010BE)
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Internal remarks:
Lethal dose in mice