EFSA Compendium of Botanicals

Draft - work in progress

Nymphaea alba L. // Castalia alba (L.) Greene // Castalia speciosa Salisb.

Family:: Nymphaeaceae
Approval state:: Approved
Number of articles retrieved:: 461
Number of processed references:: 5

Compositions

#1: alkaloids in blossoms #2: Galloyl quinic acid in rhizomes #3: gallic acid in rhizomes #4: tannins in rhizomes #5: methyl and ethyl ester of gallic acid in rhizomes #6: saponins in rhizome #7: alkaloids in rhizome #8: armepavine in leaves #9: gallic acid in flowers

Endpoint Studies

Genotoxicity

Composition #1: Modrakowski, Jerzy. Alkaloids from flowers of nymphaea alba. berichte ueber die gesamte physiologie und experimentelle pharmakologie, 1935, vol. 95, p. 123. .

Language:

English (en)
Plant part:

Flowering top (as part-nature) (A166H)
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

alkaloids in blossoms

Composition #2: Bakr, Riham Omar., Wasfi, Reham., Swilam, Noha., Sallam, Ibrahim Ezz. Characterization of the bioactive constituents of Nymphaea alba rhizomes and evaluation of anti-biofilm as well as antioxidant and cytotoxic properties. journal of medicinal plants research, 2016, vol. 10, no. 26, p. 390–401. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

70% ethanol extract from rhizomes
Substance:

quinic acid (RF-00000381-NTR)
Additional substance description:

Galloyl quinic acid
Analytical method code:

UHPLC-MS-MS (F608A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Galloyl quinic acid in rhizomes

Composition #3: Bakr, Riham Omar., Wasfi, Reham., Swilam, Noha., Sallam, Ibrahim Ezz. Characterization of the bioactive constituents of Nymphaea alba rhizomes and evaluation of anti-biofilm as well as antioxidant and cytotoxic properties. journal of medicinal plants research, 2016, vol. 10, no. 26, p. 390–401. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

70% ethanol extract from rhizomes
Substance:

gallic acid (RF-00003821-PAR)
Analytical method code:

UHPLC-MS-MS (F608A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

gallic acid in rhizomes

Composition #4: Bakr, Riham Omar., Wasfi, Reham., Swilam, Noha., Sallam, Ibrahim Ezz. Characterization of the bioactive constituents of Nymphaea alba rhizomes and evaluation of anti-biofilm as well as antioxidant and cytotoxic properties. journal of medicinal plants research, 2016, vol. 10, no. 26, p. 390–401. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

70% ethanol extract from rhizomes
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

UHPLC-MS-MS (F608A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

tannins in rhizomes

Composition #5: Bakr, Riham Omar., Wasfi, Reham., Swilam, Noha., Sallam, Ibrahim Ezz. Characterization of the bioactive constituents of Nymphaea alba rhizomes and evaluation of anti-biofilm as well as antioxidant and cytotoxic properties. journal of medicinal plants research, 2016, vol. 10, no. 26, p. 390–401. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

70% ethanol extract from rhizomes
Substance:

gallic acid (RF-00003821-PAR)
Additional substance description:

methyl and ethyl ester of gallic acid
Analytical method code:

UHPLC-MS-MS (F608A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

methyl and ethyl ester of gallic acid in rhizomes

Composition #6: Bose, A., Sahoo, M., Rout, S.S., Si, S.C. Uterotonic properties of nymphaea alba on isolated myometrium model. international journal of pharmacy and pharmaceutical sciences, 2014, vol. 6, no. 6, p. 490–493. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol 90%
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

saponins in rhizome

Composition #7: Bose, A., Sahoo, M., Rout, S.S., Si, S.C. Uterotonic properties of nymphaea alba on isolated myometrium model. international journal of pharmacy and pharmaceutical sciences, 2014, vol. 6, no. 6, p. 490–493. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol 90%
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

alkaloids in rhizome

Composition #8: Goleniewska-Furmanowa, M. Comparative leaf anatomy and alkaloid content in the nymphaeaceae bentham and hooker. monographiae botanicae, 1970, vol. 31, p. 1–56. DOI: 10.5586/MB.1970.001. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

95% ethanol
Substance:

Armepavine (RF-00011153-PAR)
Analytical method code:

Chromatographic tests (F015A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

armepavine in leaves

Composition #9: Jambor, J., Skrzypczak, L. Phenolic acids from the flowers of Nymphaea alba L.. acta societatis botanicorum poloniae, 1991, vol. 60, no. 1-2, p. 127–132. DOI: 10.5586/asbp.1991.011. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Methanol and ether
Substance:

gallic acid (RF-00003821-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) and Electron Spin Resonance (ESR) spectroscopy (F060A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

gallic acid in flowers