EFSA
ecomole
vscht
  2. Narcissus pseudonarcissus L.

Narcissus pseudonarcissus L.

Family:
Amaryllidaceae
Approval state:
Approved
Number of articles retrieved:
518
Number of processed references:
12
Compositions
#1: lycorine, 11-hydroxyvittatine, hippeastrine and 8-O-demethylmaritidine, ismine, tazettine, pretazettine, galanthamine and haemanthidin, homolycorine, 7-O-methyloduline, 7-O-methyllycorenine, 9-O-demethylhomolycorine, haemanthamine in bulb #2: puerarin in leaves #3: daidzein in bulb #4: daidzin in bulb #5: glycitin in bulb #6: Formononetin in bulb #7: genistin in leaves #8: ononin in leaves #9: galanthine in bulbs #10: methylpseudolycorine in bulbs #11: galanthamine in bulbs #12: haemanthamine in bulbs #13: lycorenine in bulbs #14: homolycorine in bulbs #15: N-demethylgalantharnine (narcissamine) in bulbs #16: pseudolycorine in bulbs #17: caranine in bulbs #18: galanthamine in bulbs #19: Haemanthamine in bulbs #20: narwedine in bulbs #21: norpluviine in bulbs #22: narciclasine in bulb #23: galanthamine in bulb #24: haemanthamine in roots #25: galanthamine in leaves #26: haemanthamine in bulb #27: galanthamine in roots #28: haemanthamine in leaves #29: narciclasine in leaves #30: haemanthamine derivates in bulbs #31: Galanthamine in bulbs #32: Narwedine in bulbs #33: Oduline in bulbs #34: O-methyllycorenine in bulbs #35: lectins in bulbs #36: Galanthamine, lycoramine, N-demethyl-galanthamine, epi-norlycoramine, O-methyloduline, vittatine, narwedine, 1-O-acetyl-10-Odemethylpluviine, 10-O-demethylpluviine, oduline, lycorenine, haemanthamine, masonine, homolycorine and N-demethyl-masonine in bulbs #37: N-demethylmasonine in bulbs #38: O-Methyloduline in bulbs #39: O-Acetylgalanthamine in bulb #40: 10-norpluviine, l-O-acetyl-10-norpluviine and 1,10-diacetyl-10-norpluviine in bulb
Endpoint Studies
#1: lethargy and vomiting in cat (severely hypothermic (33.0°C), with bradycardia (78 beats/min) and hypotension) #2: Case report: Liver and lung as target organs in oral toxicity; described case was mortal
Genotoxicity
Composition #1: Hammoda, Hala M., Abou-Donia, Amina H., Toaima, Soaad M., Shawky, Eman A. Acetylcholinesterase inhibitory activity of some amaryllidaceae plant extracts and alkaloidal isolates. alexandria journal of pharmaceutical sciences, 2011, vol. 25, no. 1, p. 26–28. .
Composition #2: Miksatkova, Petra., Lankova, Petra., Huml, Lukas., Lapcik, Oldrich. Isoflavonoids in the Amaryllidaceae family. natural product research, 2014, vol. 28, no. 10, p. 690–697. .
Composition #3: Miksatkova, Petra., Lankova, Petra., Huml, Lukas., Lapcik, Oldrich. Isoflavonoids in the Amaryllidaceae family. natural product research, 2014, vol. 28, no. 10, p. 690–697. .
Composition #4: Miksatkova, Petra., Lankova, Petra., Huml, Lukas., Lapcik, Oldrich. Isoflavonoids in the Amaryllidaceae family. natural product research, 2014, vol. 28, no. 10, p. 690–697. .
Composition #5: Miksatkova, Petra., Lankova, Petra., Huml, Lukas., Lapcik, Oldrich. Isoflavonoids in the Amaryllidaceae family. natural product research, 2014, vol. 28, no. 10, p. 690–697. .
Composition #6: Miksatkova, Petra., Lankova, Petra., Huml, Lukas., Lapcik, Oldrich. Isoflavonoids in the Amaryllidaceae family. natural product research, 2014, vol. 28, no. 10, p. 690–697. .
Composition #7: Miksatkova, Petra., Lankova, Petra., Huml, Lukas., Lapcik, Oldrich. Isoflavonoids in the Amaryllidaceae family. natural product research, 2014, vol. 28, no. 10, p. 690–697. .
Composition #8: Miksatkova, Petra., Lankova, Petra., Huml, Lukas., Lapcik, Oldrich. Isoflavonoids in the Amaryllidaceae family. natural product research, 2014, vol. 28, no. 10, p. 690–697. .
Composition #9: Fales, H.M., Giuffrida, L.D., Wildman, W.C. Alkaloids of the amaryllidaceae. VIII. The structures of narcissamine, pseudolycorine and methylpseudolycorine. journal of the american chemical society, 1956, vol. 78, no. 16, p. 4145–4150. DOI: 10.1021/ja01597a078. [DOI link]
Composition #10: Fales, H.M., Giuffrida, L.D., Wildman, W.C. Alkaloids of the amaryllidaceae. VIII. The structures of narcissamine, pseudolycorine and methylpseudolycorine. journal of the american chemical society, 1956, vol. 78, no. 16, p. 4145–4150. DOI: 10.1021/ja01597a078. [DOI link]
Composition #11: Fales, H.M., Giuffrida, L.D., Wildman, W.C. Alkaloids of the amaryllidaceae. VIII. The structures of narcissamine, pseudolycorine and methylpseudolycorine. journal of the american chemical society, 1956, vol. 78, no. 16, p. 4145–4150. DOI: 10.1021/ja01597a078. [DOI link]
Composition #12: Fales, H.M., Giuffrida, L.D., Wildman, W.C. Alkaloids of the amaryllidaceae. VIII. The structures of narcissamine, pseudolycorine and methylpseudolycorine. journal of the american chemical society, 1956, vol. 78, no. 16, p. 4145–4150. DOI: 10.1021/ja01597a078. [DOI link]
Composition #13: Fales, H.M., Giuffrida, L.D., Wildman, W.C. Alkaloids of the amaryllidaceae. VIII. The structures of narcissamine, pseudolycorine and methylpseudolycorine. journal of the american chemical society, 1956, vol. 78, no. 16, p. 4145–4150. DOI: 10.1021/ja01597a078. [DOI link]
Composition #14: Fales, H.M., Giuffrida, L.D., Wildman, W.C. Alkaloids of the amaryllidaceae. VIII. The structures of narcissamine, pseudolycorine and methylpseudolycorine. journal of the american chemical society, 1956, vol. 78, no. 16, p. 4145–4150. DOI: 10.1021/ja01597a078. [DOI link]
Composition #15: Fales, H.M., Giuffrida, L.D., Wildman, W.C. Alkaloids of the amaryllidaceae. VIII. The structures of narcissamine, pseudolycorine and methylpseudolycorine. journal of the american chemical society, 1956, vol. 78, no. 16, p. 4145–4150. DOI: 10.1021/ja01597a078. [DOI link]
Composition #16: Fales, H.M., Giuffrida, L.D., Wildman, W.C. Alkaloids of the amaryllidaceae. VIII. The structures of narcissamine, pseudolycorine and methylpseudolycorine. journal of the american chemical society, 1956, vol. 78, no. 16, p. 4145–4150. DOI: 10.1021/ja01597a078. [DOI link]
Composition #17: Cahlíková, L., Ločárek, M., Benešová, N., Kučera, R., Chlebek, J., Novák, Z., Opletal, L. Isolation and cholinesterase inhibitory activity of Narcissus extracts and amaryllidaceae alkaloid. natural product communications, 2013, vol. 8, no. 6, p. 781–785. .
Composition #18: Cahlíková, L., Ločárek, M., Benešová, N., Kučera, R., Chlebek, J., Novák, Z., Opletal, L. Isolation and cholinesterase inhibitory activity of Narcissus extracts and amaryllidaceae alkaloid. natural product communications, 2013, vol. 8, no. 6, p. 781–785. .
Composition #19: Cahlíková, L., Ločárek, M., Benešová, N., Kučera, R., Chlebek, J., Novák, Z., Opletal, L. Isolation and cholinesterase inhibitory activity of Narcissus extracts and amaryllidaceae alkaloid. natural product communications, 2013, vol. 8, no. 6, p. 781–785. .
Composition #20: Cahlíková, L., Ločárek, M., Benešová, N., Kučera, R., Chlebek, J., Novák, Z., Opletal, L. Isolation and cholinesterase inhibitory activity of Narcissus extracts and amaryllidaceae alkaloid. natural product communications, 2013, vol. 8, no. 6, p. 781–785. .
Composition #21: Cahlíková, L., Ločárek, M., Benešová, N., Kučera, R., Chlebek, J., Novák, Z., Opletal, L. Isolation and cholinesterase inhibitory activity of Narcissus extracts and amaryllidaceae alkaloid. natural product communications, 2013, vol. 8, no. 6, p. 781–785. .
Composition #22: Lubbe, Andrea., Gude, Henk., Verpoorte, Robert., Choi, Young Hae. Seasonal accumulation of major alkaloids in organs of pharmaceutical crop Narcissus Carlton . phytochemistry, 2013, vol. 88, p. 43–53. DOI: 10.1016/j.phytochem.2012.12.008. [DOI link]
Composition #23: Lubbe, Andrea., Gude, Henk., Verpoorte, Robert., Choi, Young Hae. Seasonal accumulation of major alkaloids in organs of pharmaceutical crop Narcissus Carlton . phytochemistry, 2013, vol. 88, p. 43–53. DOI: 10.1016/j.phytochem.2012.12.008. [DOI link]
Composition #24: Lubbe, Andrea., Gude, Henk., Verpoorte, Robert., Choi, Young Hae. Seasonal accumulation of major alkaloids in organs of pharmaceutical crop Narcissus Carlton . phytochemistry, 2013, vol. 88, p. 43–53. DOI: 10.1016/j.phytochem.2012.12.008. [DOI link]
Composition #25: Lubbe, Andrea., Gude, Henk., Verpoorte, Robert., Choi, Young Hae. Seasonal accumulation of major alkaloids in organs of pharmaceutical crop Narcissus Carlton . phytochemistry, 2013, vol. 88, p. 43–53. DOI: 10.1016/j.phytochem.2012.12.008. [DOI link]
Composition #26: Lubbe, Andrea., Gude, Henk., Verpoorte, Robert., Choi, Young Hae. Seasonal accumulation of major alkaloids in organs of pharmaceutical crop Narcissus Carlton . phytochemistry, 2013, vol. 88, p. 43–53. DOI: 10.1016/j.phytochem.2012.12.008. [DOI link]
Composition #27: Lubbe, Andrea., Gude, Henk., Verpoorte, Robert., Choi, Young Hae. Seasonal accumulation of major alkaloids in organs of pharmaceutical crop Narcissus Carlton . phytochemistry, 2013, vol. 88, p. 43–53. DOI: 10.1016/j.phytochem.2012.12.008. [DOI link]
Composition #28: Lubbe, Andrea., Gude, Henk., Verpoorte, Robert., Choi, Young Hae. Seasonal accumulation of major alkaloids in organs of pharmaceutical crop Narcissus Carlton . phytochemistry, 2013, vol. 88, p. 43–53. DOI: 10.1016/j.phytochem.2012.12.008. [DOI link]
Composition #29: Lubbe, Andrea., Gude, Henk., Verpoorte, Robert., Choi, Young Hae. Seasonal accumulation of major alkaloids in organs of pharmaceutical crop Narcissus Carlton . phytochemistry, 2013, vol. 88, p. 43–53. DOI: 10.1016/j.phytochem.2012.12.008. [DOI link]
Composition #30: Rachmaniah, Orchidea., Choi, Young Hae., Arruabarrena, Inaki., Vermeulen, Bas., van Spronsen, Jaap., Verpoorte, Robert., Witkarnp, Geert-Jan. Environmentally benign supercritical CO2 extraction of galanthamine from floricultural crop waste of Narcissus pseudo narcissus . journal of supercritical fluids, 2014, vol. 93, p. 7–19. DOI: 10.1016/j.supflu.2014.05.023. [DOI link]
Composition #31: Rachmaniah, Orchidea., Choi, Young Hae., Arruabarrena, Inaki., Vermeulen, Bas., van Spronsen, Jaap., Verpoorte, Robert., Witkarnp, Geert-Jan. Environmentally benign supercritical CO2 extraction of galanthamine from floricultural crop waste of Narcissus pseudo narcissus . journal of supercritical fluids, 2014, vol. 93, p. 7–19. DOI: 10.1016/j.supflu.2014.05.023. [DOI link]
Composition #32: Rachmaniah, Orchidea., Choi, Young Hae., Arruabarrena, Inaki., Vermeulen, Bas., van Spronsen, Jaap., Verpoorte, Robert., Witkarnp, Geert-Jan. Environmentally benign supercritical CO2 extraction of galanthamine from floricultural crop waste of Narcissus pseudo narcissus . journal of supercritical fluids, 2014, vol. 93, p. 7–19. DOI: 10.1016/j.supflu.2014.05.023. [DOI link]
Composition #33: Rachmaniah, Orchidea., Choi, Young Hae., Arruabarrena, Inaki., Vermeulen, Bas., van Spronsen, Jaap., Verpoorte, Robert., Witkarnp, Geert-Jan. Environmentally benign supercritical CO2 extraction of galanthamine from floricultural crop waste of Narcissus pseudo narcissus . journal of supercritical fluids, 2014, vol. 93, p. 7–19. DOI: 10.1016/j.supflu.2014.05.023. [DOI link]
Composition #34: Rachmaniah, Orchidea., Choi, Young Hae., Arruabarrena, Inaki., Vermeulen, Bas., van Spronsen, Jaap., Verpoorte, Robert., Witkarnp, Geert-Jan. Environmentally benign supercritical CO2 extraction of galanthamine from floricultural crop waste of Narcissus pseudo narcissus . journal of supercritical fluids, 2014, vol. 93, p. 7–19. DOI: 10.1016/j.supflu.2014.05.023. [DOI link]
Composition #35: KAKU, H., GOLDSTEIN, IJ. INTERACTION OF LINEAR MANNO-OLIGOSACCHARIDES WITH 3 MANNOSE-SPECIFIC BULB LECTINS - COMPARISON WITH MANNOSE GLUCOSE-BINDING LECTINS . carbohydrate research, 1992, vol. 229, no. 2, p. 337–346. DOI: 10.1016/S0008-6215(00)90579-2. [DOI link]
Composition #36: KREH, M., MATUSCH, R., WITTE, L. CAPILLARY GAS-CHROMATOGRAPHY MASS-SPECTROMETRY OF AMARYLLIDACEAE ALKALOIDS . phytochemistry, 1995, vol. 38, no. 3, p. 773–776. DOI: 10.1016/0031-9422(94)00725-9. [DOI link]
Composition #37: KREH, M., MATUSCH, R. O-METHYLODULINE AND N-DEMETHYLMASONINE, ALKALOIDS FROM NARCISSUS-PSEUDONARCISSUS . phytochemistry, 1995, vol. 38, no. 6, p. 1533–1535. DOI: 10.1016/0031-9422(94)00827-G. [DOI link]
Composition #38: KREH, M., MATUSCH, R. O-METHYLODULINE AND N-DEMETHYLMASONINE, ALKALOIDS FROM NARCISSUS-PSEUDONARCISSUS . phytochemistry, 1995, vol. 38, no. 6, p. 1533–1535. DOI: 10.1016/0031-9422(94)00827-G. [DOI link]
Composition #39: KREH, M., MATUSCH, R., WITTE, L. ACETYLATED ALKALOIDS FROM NARCISSUS-PSEUDONARCISSUS. phytochemistry, 1995, vol. 40, no. 4, p. 1303–1306. DOI: 10.1016/0031-9422(95)00465-J. [DOI link]
Composition #40: KREH, M., MATUSCH, R., WITTE, L. ACETYLATED ALKALOIDS FROM NARCISSUS-PSEUDONARCISSUS. phytochemistry, 1995, vol. 40, no. 4, p. 1303–1306. DOI: 10.1016/0031-9422(95)00465-J. [DOI link]
Endpoint study #1: Saxon-Buri, S. Daffodil toxicosis in an adult cat. canadian veterinary journal, 2004, vol. 45, no. 3, p. 248–250. .
Endpoint study #2: JaspersenSchib, R., Theus, L., GuirguisOeschger, M., Gossweiler, B., MeierAbt, PJ. Acute poisonings with toxic giants in Switzerland between 1966 and 1994. schweizerische medizinische wochenschrift, 1996, vol. 126, no. 25, p. 1085–1098. .