EFSA Compendium of Botanicals

Draft - work in progress

Magnolia kobus DC.

Family:: Magnoliaceae
Approval state:: Approved
Number of articles retrieved:: 224
Number of processed references:: 10

Compositions

#1: cineole in leaves and branches #2: estragole (methylchavicol) in leaves and branches #3: eugenol in leaves and branches #4: kobusin in flos #5: epieudesmine in flos #6: Yangambin (lirioresinol B dimethyl ether) in flos #7: aschantin in flos #8: magnolin in flos #9: epimagnolin in flos #10: fargesin in flos #11: burchellin in flos #12: silicifoline in stems #13: pinoresinol #14: asimilobine in leaves #15: alkaloids in leaves #16: liriodenine in leaves #17: anonaine in leaves #18: syringaresinol in leaves #19: liriodenine in branches #20: anonaine in leaves #21: eudesmin in seeds #22: oplopanone, zingibertriol in seeds #23: kobusin in seeds #24: faegesol, magnostellin, sesamine in seeds #25: parthenolide in seeds #26: kobusin in bark #27: magnolin in bark #28: isoquinoline alkaloids in bark #29: yangambin in bark #30: isobisparthenolidine, ibispathenolidine n roots #31: constunolide in roots #32: parthenolide in roots #33: magnocurarine in leaves #34: magnoflorine in stem barks and twigs

Endpoint Studies

Genotoxicity

Composition #1: Fujita, Yasuji. Constituents of essential oils from Magnolia kobus and M. salicifolia. j. japan. botan, 1955, vol. 30, p. 188–90. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydrodistillation
Substance:

1,8-cineole (RF-00003470-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

cineole in leaves and branches

Composition #2: Fujita, Yasuji. Constituents of essential oils from Magnolia kobus and M. salicifolia. j. japan. botan, 1955, vol. 30, p. 188–90. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydrodistillation
Substance:

Estragole (RF-00003806-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

estragole (methylchavicol) in leaves and branches

Composition #3: Fujita, Yasuji. Constituents of essential oils from Magnolia kobus and M. salicifolia. j. japan. botan, 1955, vol. 30, p. 188–90. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydrodistillation
Substance:

Eugenol (RF-00003807-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

eugenol in leaves and branches

Composition #4: Fang, Zhe., Shen, Chang Min., Moon, Dong Cheul., Son, Kun Ho., Son, Jong Keun., Woo, Mi Hee. Quantitative and pattern recognition analyses for the quality evaluation of Magnoliae Flos by HPLC. bulletin of the korean chemical society, 2010, vol. 31, no. 11, p. 3371–3381. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methylene chloride
Substance:

Kobusin (RF-00013327-PAR)
Analytical method code:

HPLC-UV (F021A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.0913-0.1338
Internal remarks:

kobusin in flos

Composition #5: Fang, Zhe., Shen, Chang Min., Moon, Dong Cheul., Son, Kun Ho., Son, Jong Keun., Woo, Mi Hee. Quantitative and pattern recognition analyses for the quality evaluation of Magnoliae Flos by HPLC. bulletin of the korean chemical society, 2010, vol. 31, no. 11, p. 3371–3381. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methylene chloride
Substance:

(+)-Epieudesmine (RF-00011057-PAR)
Analytical method code:

HPLC-UV (F021A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.0024-0.0127
Internal remarks:

epieudesmine in flos

Composition #6: Fang, Zhe., Shen, Chang Min., Moon, Dong Cheul., Son, Kun Ho., Son, Jong Keun., Woo, Mi Hee. Quantitative and pattern recognition analyses for the quality evaluation of Magnoliae Flos by HPLC. bulletin of the korean chemical society, 2010, vol. 31, no. 11, p. 3371–3381. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methylene chloride
Substance:

Yangambin (RF-00011058-PAR)
Additional substance description:

synon. for lirioresinol B dimethyl ether
Analytical method code:

HPLC-UV (F021A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.3415-0.8976
Internal remarks:

Yangambin (lirioresinol B dimethyl ether) in flos

Composition #7: Fang, Zhe., Shen, Chang Min., Moon, Dong Cheul., Son, Kun Ho., Son, Jong Keun., Woo, Mi Hee. Quantitative and pattern recognition analyses for the quality evaluation of Magnoliae Flos by HPLC. bulletin of the korean chemical society, 2010, vol. 31, no. 11, p. 3371–3381. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methylene chloride
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

aschantin
Analytical method code:

HPLC-UV (F021A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.0003-0.0004
Internal remarks:

aschantin in flos

Composition #8: Fang, Zhe., Shen, Chang Min., Moon, Dong Cheul., Son, Kun Ho., Son, Jong Keun., Woo, Mi Hee. Quantitative and pattern recognition analyses for the quality evaluation of Magnoliae Flos by HPLC. bulletin of the korean chemical society, 2010, vol. 31, no. 11, p. 3371–3381. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methylene chloride
Substance:

Magnoline (RF-00011167-PAR)
Analytical method code:

HPLC-UV (F021A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.0091-0.0316
Internal remarks:

magnolin in flos

Composition #9: Fang, Zhe., Shen, Chang Min., Moon, Dong Cheul., Son, Kun Ho., Son, Jong Keun., Woo, Mi Hee. Quantitative and pattern recognition analyses for the quality evaluation of Magnoliae Flos by HPLC. bulletin of the korean chemical society, 2010, vol. 31, no. 11, p. 3371–3381. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methylene chloride
Substance:

epi-Magnolin A (RF-00011385-PAR)
Additional substance description:

epimagnolin
Analytical method code:

HPLC-UV (F021A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.0014-0.0016
Internal remarks:

epimagnolin in flos

Composition #10: Fang, Zhe., Shen, Chang Min., Moon, Dong Cheul., Son, Kun Ho., Son, Jong Keun., Woo, Mi Hee. Quantitative and pattern recognition analyses for the quality evaluation of Magnoliae Flos by HPLC. bulletin of the korean chemical society, 2010, vol. 31, no. 11, p. 3371–3381. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methylene chloride
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

fargesin
Analytical method code:

HPLC-UV (F021A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.0124-0.0267
Internal remarks:

fargesin in flos

Composition #11: Fang, Zhe., Shen, Chang Min., Moon, Dong Cheul., Son, Kun Ho., Son, Jong Keun., Woo, Mi Hee. Quantitative and pattern recognition analyses for the quality evaluation of Magnoliae Flos by HPLC. bulletin of the korean chemical society, 2010, vol. 31, no. 11, p. 3371–3381. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methylene chloride
Substance:

Benzofurans (RF-00010791-PAR)
Additional substance description:

burchellin
Analytical method code:

HPLC-UV (F021A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.1167-1.0263
Internal remarks:

burchellin in flos

Composition #12: Okumura Wakaba., Aoki Dan., Matsushita Yasuyuki., Yoshida Masato., Fukushima Kazuhiko. Distribution of salicifoline in freeze-fixed stems of Magnolia kobus as observed by cryo-TOF-SIMS. scientific reports, 2017, vol. 7, no. 1, p. 5939. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Raw, no heat treatment (A07HS)
Substance:

salicifoline (RF-00004036-PAR)
Additional substance description:

freeze-fixed stem
Analytical method code:

Microscopic detection (F536A)
Analytical method - additional description:

Cryo-TOF-SIMS/SEM analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

silicifoline in stems

Composition #13: Miyauchi, T., Ozawa, S. Formation of (+)-eudesmin in Magnolia kobus DC. var. Borealis sarg.. phytochemistry, 1998, vol. 47, no. 4, p. 665–670. DOI: 10.1016/S0031-9422(97)00458-5. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

Pinoresinol (RF-00011088-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

pinoresinol

Composition #14: Ziyaev, R., Shtonda, NI., Sturua, MD., Abdusamatov, A., Tsakadze, DM. Alkaloids of some Magnolia species. chemistry of natural compounds, 1999, vol. 35, no. 3, p. 366–367. DOI: 10.1007/BF02234867. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

10% amonia solution
Substance:

asimilobine (RF-00004160-PAR)
Analytical method code:

Unspecified (F598A)
Analytical method - additional description:

chlorophorm method
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

asimilobine in leaves

Composition #15: Ziyaev, R., Shtonda, NI., Sturua, MD., Abdusamatov, A., Tsakadze, DM. Alkaloids of some Magnolia species. chemistry of natural compounds, 1999, vol. 35, no. 3, p. 366–367. DOI: 10.1007/BF02234867. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

10% amonia solution
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

oxalaurenine, remerine, lanuginosine
Analytical method code:

Unspecified (F598A)
Analytical method - additional description:

chlorophorm method
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.019-0.31
Internal remarks:

alkaloids in leaves

Composition #16: Ziyaev, R., Shtonda, NI., Sturua, MD., Abdusamatov, A., Tsakadze, DM. Alkaloids of some Magnolia species. chemistry of natural compounds, 1999, vol. 35, no. 3, p. 366–367. DOI: 10.1007/BF02234867. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

10% amonia solution
Substance:

liriodenine (RF-00003473-PAR)
Analytical method code:

Unspecified (F598A)
Analytical method - additional description:

chlorophorm method
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

liriodenine in leaves

Composition #17: Ziyaev, R., Shtonda, NI., Sturua, MD., Abdusamatov, A., Tsakadze, DM. Alkaloids of some Magnolia species. chemistry of natural compounds, 1999, vol. 35, no. 3, p. 366–367. DOI: 10.1007/BF02234867. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

10% amonia solution
Substance:

anonaine (RF-00004150-PAR)
Analytical method code:

Unspecified (F598A)
Analytical method - additional description:

chlorophorm method
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

anonaine in leaves

Composition #18: Ziyaev, R., Shtonda, NI., Sturua, MD., Abdusamatov, A., Tsakadze, DM. Alkaloids of some Magnolia species. chemistry of natural compounds, 1999, vol. 35, no. 3, p. 366–367. DOI: 10.1007/BF02234867. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

10% amonia solution
Substance:

syringaresinol (RF-00011386-PAR)
Analytical method code:

Unspecified (F598A)
Analytical method - additional description:

chlorophorm method
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

syringaresinol in leaves

Composition #19: Ziyaev, R., Shtonda, NI., Sturua, MD., Abdusamatov, A., Tsakadze, DM. Alkaloids of some Magnolia species. chemistry of natural compounds, 1999, vol. 35, no. 3, p. 366–367. DOI: 10.1007/BF02234867. [DOI link]

Language:

English (en)
Plant part:

Wood (as part-nature) (A166P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

10% amonia solution
Substance:

liriodenine (RF-00003473-PAR)
Analytical method code:

Unspecified (F598A)
Analytical method - additional description:

chlorophorm method
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.12-0.18
Internal remarks:

liriodenine in branches

Composition #20: Ziyaev, R., Shtonda, NI., Sturua, MD., Abdusamatov, A., Tsakadze, DM. Alkaloids of some Magnolia species. chemistry of natural compounds, 1999, vol. 35, no. 3, p. 366–367. DOI: 10.1007/BF02234867. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

10% amonia solution
Substance:

anonaine (RF-00004150-PAR)
Analytical method code:

Unspecified (F598A)
Analytical method - additional description:

chlorophorm method
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

anonaine in leaves

Composition #21: Takahashi, H., Yoshioka, S., Kawano, S., Azuma, H., Fukuyama, Y. Lignans and sesquiterpenes from Magnolia praecocissima. chemical & pharmaceutical bulletin, 2002, vol. 50, no. 4, p. 541–543. DOI: 10.1248/cpb.50.541. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

(+)-Epieudesmine (RF-00011057-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

eudesmin in seeds

Composition #22: Takahashi, H., Yoshioka, S., Kawano, S., Azuma, H., Fukuyama, Y. Lignans and sesquiterpenes from Magnolia praecocissima. chemical & pharmaceutical bulletin, 2002, vol. 50, no. 4, p. 541–543. DOI: 10.1248/cpb.50.541. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Sesquiterpene lactones (RF-00004319-PAR)
Additional substance description:

oplopanone, zingibertriol
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

oplopanone, zingibertriol in seeds

Composition #23: Takahashi, H., Yoshioka, S., Kawano, S., Azuma, H., Fukuyama, Y. Lignans and sesquiterpenes from Magnolia praecocissima. chemical & pharmaceutical bulletin, 2002, vol. 50, no. 4, p. 541–543. DOI: 10.1248/cpb.50.541. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Kobusin (RF-00013327-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

kobusin in seeds

Composition #24: Takahashi, H., Yoshioka, S., Kawano, S., Azuma, H., Fukuyama, Y. Lignans and sesquiterpenes from Magnolia praecocissima. chemical & pharmaceutical bulletin, 2002, vol. 50, no. 4, p. 541–543. DOI: 10.1248/cpb.50.541. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

faegesol, magnostellin, sesamine
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

faegesol, magnostellin, sesamine in seeds

Composition #25: Takahashi, H., Yoshioka, S., Kawano, S., Azuma, H., Fukuyama, Y. Lignans and sesquiterpenes from Magnolia praecocissima. chemical & pharmaceutical bulletin, 2002, vol. 50, no. 4, p. 541–543. DOI: 10.1248/cpb.50.541. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

parthenolide (RF-00003531-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

parthenolide in seeds

Composition #26: Lee, Hak-Ju., Seo, Seon-Mi., Lee, Oh-Kyu., Jo, Hyun-Jin., Kang, Ha-Young., Choi, Don-Ha., Paik, Ki-Hyon., Khan, Merajuddin. Lignans from the Bark of Magnolia kobus. helvetica chimica acta, 2008, vol. 91, no. 12, p. 2361–2366. .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

95% EtOH
Substance:

Kobusin (RF-00013327-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

TLC, UV, MNR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

kobusin in bark

Composition #27: Lee, Hak-Ju., Seo, Seon-Mi., Lee, Oh-Kyu., Jo, Hyun-Jin., Kang, Ha-Young., Choi, Don-Ha., Paik, Ki-Hyon., Khan, Merajuddin. Lignans from the Bark of Magnolia kobus. helvetica chimica acta, 2008, vol. 91, no. 12, p. 2361–2366. .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

95% EtOH
Substance:

Magnoline (RF-00011167-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

TLC, UV, MNR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

magnolin in bark

Composition #28: Lee, Hak-Ju., Seo, Seon-Mi., Lee, Oh-Kyu., Jo, Hyun-Jin., Kang, Ha-Young., Choi, Don-Ha., Paik, Ki-Hyon., Khan, Merajuddin. Lignans from the Bark of Magnolia kobus. helvetica chimica acta, 2008, vol. 91, no. 12, p. 2361–2366. .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

95% EtOH
Substance:

Isoquinoline alkaloids (RF-00004391-PAR)
Additional substance description:

(þ)-(7a,7’a,8a,8’a)-3’,4,4’,5,5’-Pentamethoxy-7,9’: 7’,9-diepoxylignan-3-ol; (þ)-(7a,7’a,8a,8’a)-4,5-Dimethoxy-3’,4’-(methylenedioxy)-7,9’: 7’,9-diepoxylignan-3-ol; (þ)-Sesamin; (þ)-Eudesmin
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

TLC, UV, MNR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

isoquinoline alkaloids in bark

Composition #29: Lee, Hak-Ju., Seo, Seon-Mi., Lee, Oh-Kyu., Jo, Hyun-Jin., Kang, Ha-Young., Choi, Don-Ha., Paik, Ki-Hyon., Khan, Merajuddin. Lignans from the Bark of Magnolia kobus. helvetica chimica acta, 2008, vol. 91, no. 12, p. 2361–2366. .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

95% EtOH
Substance:

Yangambin (RF-00011058-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

TLC, UV, MNR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

yangambin in bark

Composition #30: Park, Hee Wook., Lee, Jae Hyeok., Choi, Sang-Un., Baek, Nam-In., Kim, Sung-Hoon., Yang, Jae Heon., Kim, Dae Keun. Cytotoxic Germacranolide Sesquiterpenes from the Bark of Magnolia kobus. archives of pharmacal research, 2010, vol. 33, no. 1, p. 71–74. DOI: 10.1007/s12272-010-2227-5. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH
Substance:

Sesquiterpene lactones (RF-00004319-PAR)
Additional substance description:

Isobisparthenolidine, bisparthenolidine
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

isobisparthenolidine, ibispathenolidine n roots

Composition #31: Park, Hee Wook., Lee, Jae Hyeok., Choi, Sang-Un., Baek, Nam-In., Kim, Sung-Hoon., Yang, Jae Heon., Kim, Dae Keun. Cytotoxic Germacranolide Sesquiterpenes from the Bark of Magnolia kobus. archives of pharmacal research, 2010, vol. 33, no. 1, p. 71–74. DOI: 10.1007/s12272-010-2227-5. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH
Substance:

costunolide (RF-00003753-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

constunolide in roots

Composition #32: Park, Hee Wook., Lee, Jae Hyeok., Choi, Sang-Un., Baek, Nam-In., Kim, Sung-Hoon., Yang, Jae Heon., Kim, Dae Keun. Cytotoxic Germacranolide Sesquiterpenes from the Bark of Magnolia kobus. archives of pharmacal research, 2010, vol. 33, no. 1, p. 71–74. DOI: 10.1007/s12272-010-2227-5. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH
Substance:

parthenolide (RF-00003531-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

parthenolide in roots

Composition #33: FURMANOWA, M., JOZEFOWICZ, J. ALKALOIDS AS TAXONOMIC MARKERS IN SOME SPECIES OF MAGNOLIA L AND LIRIODENDRON L . acta societatis botanicorum poloniae, 1980, vol. 49, no. 4, p. 527–535. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

96% ethanol
Substance:

magnocurarine (RF-00003918-PAR)
Analytical method code:

Chromatographic tests (F015A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

magnocurarine in leaves

Composition #34: SLAVIK, J., SLAVIKOVA, L. QUATERNARY ISOQUINOLINE ALKALOIDS AND SOME DITERPENOID ALKALOIDS IN PLANTS OF THE CZECH-REPUBLIC . collection of czechoslovak chemical communications, 1995, vol. 60, no. 6, p. 1034–1041. DOI: 10.1135/cccc19951034. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

magnoflorine (RF-00003919-PAR)
Analytical method code:

HPLC-UV (F021A)
Analytical method - additional description:

UV, IR, mass spectra, TLC
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.044
Internal remarks:

magnoflorine in stem barks and twigs