Composition #1: Wagner, Hildebert., Hoerhammer, Ludwig., Frank, U. Components of drug plants with hormone-like and antihormone-like activities. III. Lithospermic acid, the antihormonally active principle of Lycopus europaeus and Symphytum officinale. arzneimittel-forschung, 1970, vol. 20, no. 5, p. 705–13. .
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Substance:
[RS]-({3,3-dimethyl-5-[(methylsulfonyl)oxy]-2,3-dihydro-1-benzofuran-2-yl}oxy)acetic acid (RF-00006247-PAR)
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Additional substance description:
Lithospermic acid
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Lithospermic acid
Composition #2: Roeder, E., Wiedenfeld, H. Plants containing pyrrolizidine alkaloids used in the Traditional Indian medicine - Including Ayurveda. pharmazie, 2013, vol. 68, no. 2, p. 83–92. DOI: 10.1691/ph.2013.2706.
[
DOI link]
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Substance:
Pyrrolizidine alkaloids (RF-00000230-TOX)
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Additional substance description:
lithosenine and 3’–acetyllithosenine
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Pyrrolizidine alkaloids (lithosenine and 3’–acetyllithosenine)
Composition #3: Dresler, Slawomir., Szymczak, Grazyna., Wojcik, Malgorzata. Comparison of some secondary metabolite content in the seventeen species of the Boraginaceae family. . pharmaceutical biology, 2017, vol. 55, no. 1, p. 691–695. DOI: 10.1080/13880209.2016.1265986.
[
DOI link]
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Plant part:
Shoot (as part-nature) (A067T)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
methanol and hexane
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Substance:
shikonin (RF-00011315-PAR)
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Analytical method code:
Capillary (Zone) Electrophoresis (CE or CZE) (F071A)
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Analytical method - additional description:
High performance capillary electrophoresis (HPCE)
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Result unit:
Milligram/gram (G060A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
0.079
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Internal remarks:
shikonin in shoots
Composition #4: KRENN, L., WIEDENFELD, H., ROEDER, E. PYRROLIZIDINE ALKALOIDS FROM LITHOSPERMUM-OFFICINALE. phytochemistry, 1994, vol. 37, no. 1, p. 275–277. DOI: 10.1016/0031-9422(94)85040-2.
[
DOI link]
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
CH,C12-MeOH-NH,OH (25%)
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Substance:
acetyllithosenine (RF-00003664-PAR)
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Analytical method code:
Gaschromatography (GC) (F037A)
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Result unit:
Milligram/gram (G060A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
0.031
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Internal remarks:
Acetyllithosenine in aerial parts
Composition #5: KRENN, L., WIEDENFELD, H., ROEDER, E. PYRROLIZIDINE ALKALOIDS FROM LITHOSPERMUM-OFFICINALE. phytochemistry, 1994, vol. 37, no. 1, p. 275–277. DOI: 10.1016/0031-9422(94)85040-2.
[
DOI link]
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
CH,C12-MeOH-NH,OH (25%)
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Substance:
Pyrrolizidine alkaloids (RF-00000230-TOX)
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Additional substance description:
Lifhosenine
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Analytical method code:
Gaschromatography (GC) (F037A)
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Result unit:
Milligram/gram (G060A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
0.047
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Internal remarks:
Lifhosenine in aerial parts
