EFSA Compendium of Botanicals

Draft - work in progress

Ligustrum vulgare L.

Family:: Oleaceae
Approval state:: Approved
Number of articles retrieved:: 591
Number of processed references:: 2

Compositions

Endpoint Studies

#1: Digestive symptoms of berries (nausea, vomiting and abdominal pain)

Genotoxicity

Composition #1: WILLEMS, M. A GLUCOSIDIC ALKALOID ARTIFACT, ORIGINATED FROM SECOIRIDOID GLUCOSIDES FROM FRUITS OF LIGUSTRUM-VULGARE L . archiv der pharmazie, 1988, vol. 321, no. 6, p. 357–358. DOI: 10.1002/ardp.19883210612. [DOI link]

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

5% H2SO4 and NH3
Substance:

pyridine alkaloids (RF-00010801-PAR)
Additional substance description:

jasminine and other alkaloids
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR+TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

pyridine alkaloids in berries

Endpoint study #1: Czerwinska, Monika E., Ziarek, Marlena., Bazylko, Agnieszka., Osinska, Ewa., Kiss, Anna K. Quantitative Determination of Secoiridoids and Phenylpropanoids in Different Extracts of Ligustrum Vulgare L. Leaves by a Validated HPTLC-Photodensitometry Method . phytochemical analysis, 2015, vol. 26, no. 4, p. 253–260. DOI: 10.1002/pca.2558. [DOI link]

Study relevance:

Human health
Plant part:

Fruit peel (as part-nature) (A067G)
Type of toxicological test:

case report (CHD060TT)
Tested organism:

Human (as organism) (A056J)
Sex:

No data
Route of exposure:

ORAL: UNSPECIFIED (OECD2234PL)
Control groups used:

no data
Endpoint measured:

Dose not reported (CHD066EP)
Critical effect:

Digestive (TOX18A)
Target tissue:

Digestive (TT002A)
Effect description:

nausea, vomiting and abdominal pain
Effect or parameter linked to the endpoint:

food efficiency (CHD021BE)
Internal remarks:

Digestive symptoms of berries (nausea, vomiting and abdominal pain)