EFSA Compendium of Botanicals

Draft - work in progress

Lavandula latifolia Medik. // Lavandula spica auct., non L.

Family:: Lamiaceae
Approval state:: Approved
Number of articles retrieved:: 253
Number of processed references:: 10

Compositions

Endpoint Studies

Genotoxicity

Composition #1: De Pascual Teresa, J., Ovejero, Juan., Anaya, Josefa., Caballero, Esther., Hernandez, Jose Maria., Cruz Caballero, Maria. Chemical composition of the Spanish spike oil. planta medica, 1989, vol. 55, no. 4, p. 398–9. .

Language:

English (en)
Plant part:

Flowering top (as part-nature) (A166H)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

steam distillation
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

IR, NMR, TLC
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

8-15
Internal remarks:

camphor in essential oil

Composition #2: De Pascual Teresa, J., Ovejero, Juan., Anaya, Josefa., Caballero, Esther., Hernandez, Jose Maria., Cruz Caballero, Maria. Chemical composition of the Spanish spike oil. planta medica, 1989, vol. 55, no. 4, p. 398–9. .

Language:

English (en)
Plant part:

Flowering top (as part-nature) (A166H)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

steam distillation
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

IR, NMR, TLC
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

34.9-36.3
Internal remarks:

1,8-cineole in essential oil

Composition #3: Mizrahi, I., Juarez, MA., Elechosa, MA., Bandoni, AL., Nunez, M., Caffini, N., Bernath, J., Craker, L., Jatisatienr, A., Gilberti, G. Composition and quality of essential oils obtained from crops of Lavandula spp. of Argentina . proceedings of the 2nd world congress on medicinal and aromatic plants (wocmap-2): biological resources, sustainable use conservation and ethnobotany, 1999, no. 500, p. 119–125. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

distillation
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

Gaschromatography (GC) (F037A)
Result unit:

Percent (G138A)
Result expression:

Reconstituted product (B007A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

19.0 - 37.6
Internal remarks:

1,8-cineole in essential oil

Composition #4: Mizrahi, I., Juarez, MA., Elechosa, MA., Bandoni, AL., Nunez, M., Caffini, N., Bernath, J., Craker, L., Jatisatienr, A., Gilberti, G. Composition and quality of essential oils obtained from crops of Lavandula spp. of Argentina . proceedings of the 2nd world congress on medicinal and aromatic plants (wocmap-2): biological resources, sustainable use conservation and ethnobotany, 1999, no. 500, p. 119–125. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

distillation
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

Gaschromatography (GC) (F037A)
Result unit:

Percent (G138A)
Result expression:

Reconstituted product (B007A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

19.7 - 23.5
Internal remarks:

camphor in essential oil

Composition #5: Mizrahi, I., Juarez, MA., Elechosa, MA., Bandoni, AL., Nunez, M., Caffini, N., Bernath, J., Craker, L., Jatisatienr, A., Gilberti, G. Composition and quality of essential oils obtained from crops of Lavandula spp. of Argentina . proceedings of the 2nd world congress on medicinal and aromatic plants (wocmap-2): biological resources, sustainable use conservation and ethnobotany, 1999, no. 500, p. 119–125. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

distillation
Substance:

Lavandulyl acetate (RF-00002094-PAR)
Analytical method code:

Gaschromatography (GC) (F037A)
Result unit:

Percent (G138A)
Result expression:

Reconstituted product (B007A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.1 - 1.5
Internal remarks:

lavandulyl acetate in essential oil

Composition #6: Barazandeh, MM. Essential oil composition of Lavandula latifolia Medik from Iran. journal of essential oil research, 2002, vol. 14, no. 2, p. 103–104. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

fresh flowers, steam distillation
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

18.8
Internal remarks:

1.8-cineol in fresh flower essential oil

Composition #7: Barazandeh, MM. Essential oil composition of Lavandula latifolia Medik from Iran. journal of essential oil research, 2002, vol. 14, no. 2, p. 103–104. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

fresh flowers, steam distillation
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

4.4
Internal remarks:

camphor in fresh flower essential oil

Composition #8: Barazandeh, MM. Essential oil composition of Lavandula latifolia Medik from Iran. journal of essential oil research, 2002, vol. 14, no. 2, p. 103–104. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

dry flowers, steam distillation
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

20.9
Internal remarks:

1-8-cineol in dry flower essential oil

Composition #9: Barazandeh, MM. Essential oil composition of Lavandula latifolia Medik from Iran. journal of essential oil research, 2002, vol. 14, no. 2, p. 103–104. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

fresh flowers, steam distillation
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.3
Internal remarks:

myrcene in fresh flower essential oil

Composition #10: Barazandeh, MM. Essential oil composition of Lavandula latifolia Medik from Iran. journal of essential oil research, 2002, vol. 14, no. 2, p. 103–104. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

dry flowers, steam distillation
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.4
Internal remarks:

myrcene in dry flower essential oil

Composition #11: Barazandeh, MM. Essential oil composition of Lavandula latifolia Medik from Iran. journal of essential oil research, 2002, vol. 14, no. 2, p. 103–104. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

dry flowers, steam distillation
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

4.5
Internal remarks:

camphor in dry flower essential oil

Composition #12: Salido, S., Altarejos, J., Nogueras, M., Sanchez, A., Luque, P. Chemical composition and seasonal variations of spike lavender oil from Southern Spain . journal of essential oil research, 2004, vol. 16, no. 3, p. 206–210. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

steam distillation
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

28-34.9
Internal remarks:

1,8-cineol in essential oil

Composition #13: Salido, S., Altarejos, J., Nogueras, M., Sanchez, A., Luque, P. Chemical composition and seasonal variations of spike lavender oil from Southern Spain . journal of essential oil research, 2004, vol. 16, no. 3, p. 206–210. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

steam distillation
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

10.8-23.2
Internal remarks:

camphor in essential oil

Composition #14: Alatrache, A., Jamoussi, B., Tarhouni, R., Abdrabba, M. Analysis of the essential oil of Lavandula latifolia from Tunisia. journal of essential oil bearing plants, 2007, vol. 10, no. 6, p. 446–452. .

Language:

English (en)
Plant part:

Flowering top (as part-nature) (A166H)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

steam distillation
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

11.7
Internal remarks:

1.8-cineol in essential oil

Composition #15: Alatrache, A., Jamoussi, B., Tarhouni, R., Abdrabba, M. Analysis of the essential oil of Lavandula latifolia from Tunisia. journal of essential oil bearing plants, 2007, vol. 10, no. 6, p. 446–452. .

Language:

English (en)
Plant part:

Flowering top (as part-nature) (A166H)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

steam distillation
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

12.4
Internal remarks:

camphor in essential oil

Composition #16: Alatrache, A., Jamoussi, B., Tarhouni, R., Abdrabba, M. Analysis of the essential oil of Lavandula latifolia from Tunisia. journal of essential oil bearing plants, 2007, vol. 10, no. 6, p. 446–452. .

Language:

English (en)
Plant part:

Flowering top (as part-nature) (A166H)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

steam distillation
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.1
Internal remarks:

myrcene in essential oil

Composition #17: Herraiz-Penalver, David., Angeles Cases, Maria., Varela, Federico., Navarrete, Paloma., Sanchez-Vioque, Raul., Usano-Alemany, Jaime. Chemical characterization of Lavandula latifolia Medik. essential oil from Spanish wild populations . biochemical systematics and ecology, 2013, vol. 46, p. 59–68. DOI: 10.1016/j.bse.2012.09.018. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

elemicin (RF-00003787-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.04-1.76
Internal remarks:

elemicin in flower ess oil

Composition #18: Herraiz-Penalver, David., Angeles Cases, Maria., Varela, Federico., Navarrete, Paloma., Sanchez-Vioque, Raul., Usano-Alemany, Jaime. Chemical characterization of Lavandula latifolia Medik. essential oil from Spanish wild populations . biochemical systematics and ecology, 2013, vol. 46, p. 59–68. DOI: 10.1016/j.bse.2012.09.018. [DOI link]

Language:

English (en)
Plant part:

Flowering top (as part-nature) (A166H)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

6.6-57.1
Internal remarks:

1,8-cineole in flower ess oil

Composition #19: Herraiz-Penalver, David., Angeles Cases, Maria., Varela, Federico., Navarrete, Paloma., Sanchez-Vioque, Raul., Usano-Alemany, Jaime. Chemical characterization of Lavandula latifolia Medik. essential oil from Spanish wild populations . biochemical systematics and ecology, 2013, vol. 46, p. 59–68. DOI: 10.1016/j.bse.2012.09.018. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.06-46.69
Internal remarks:

camphor in flower ess oil

Composition #20: Herraiz-Penalver, David., Angeles Cases, Maria., Varela, Federico., Navarrete, Paloma., Sanchez-Vioque, Raul., Usano-Alemany, Jaime. Chemical characterization of Lavandula latifolia Medik. essential oil from Spanish wild populations . biochemical systematics and ecology, 2013, vol. 46, p. 59–68. DOI: 10.1016/j.bse.2012.09.018. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

(-)-globulol (RF-00003756-PAR)
Additional substance description:

ledol, ledum camphor aka
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.44-1.3
Internal remarks:

globulol (ledol) in flower ess oil

Composition #21: Mendez-Tovar, Ines., Sponza, Silvia., Asensio-S-Manzanera, Carmen., Schmiderer, Corinna., Novak, Johannes. Volatile fraction differences for Lamiaceae species using different extraction methodologies . journal of essential oil research, 2015, vol. 27, no. 6, p. 497–505. DOI: 10.1080/10412905.2015.1064039. [DOI link]

Language:

English (en)
Plant part:

Flowering top (as part-nature) (A166H)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

leaves and flowers, solvent extraction, dichloromethane
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-FID-MS (F607A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

9.82-9.18
Internal remarks:

camphor in essential oil, solvent extraction

Composition #22: Mendez-Tovar, Ines., Sponza, Silvia., Asensio-S-Manzanera, Carmen., Schmiderer, Corinna., Novak, Johannes. Volatile fraction differences for Lamiaceae species using different extraction methodologies . journal of essential oil research, 2015, vol. 27, no. 6, p. 497–505. DOI: 10.1080/10412905.2015.1064039. [DOI link]

Language:

English (en)
Plant part:

Flowering top (as part-nature) (A166H)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

leaves and flowers, microdistillation
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-FID-MS (F607A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

8.56-9.64
Internal remarks:

camphor in essential oil, microdistillation

Composition #23: Mendez-Tovar, Ines., Sponza, Silvia., Asensio-S-Manzanera, Carmen., Schmiderer, Corinna., Novak, Johannes. Volatile fraction differences for Lamiaceae species using different extraction methodologies . journal of essential oil research, 2015, vol. 27, no. 6, p. 497–505. DOI: 10.1080/10412905.2015.1064039. [DOI link]

Language:

English (en)
Plant part:

Flowering top (as part-nature) (A166H)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

leaves and flowers, hydrodistillation
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-FID-MS (F607A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

7.94-9.46
Internal remarks:

camphor in essential oil, hydrodistillation

Composition #24: Mendez-Tovara, I., Novak, J., Sponza, S., Herrero, B., Asensio-S-Manzanera, M. C. Variability in essential oil composition of wild populations of Labiatae species collected in Spain . industrial crops and products, 2016, vol. 79, p. 18–28. DOI: 10.1016/j.indcrop.2015.10.009. [DOI link]

Language:

English (en)
Plant part:

Flowering top (as part-nature) (A166H)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-FID-MS (F607A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.45-16.14
Internal remarks:

camphor in essential oil

Composition #25: Mendez-Tovara, I., Novak, J., Sponza, S., Herrero, B., Asensio-S-Manzanera, M. C. Variability in essential oil composition of wild populations of Labiatae species collected in Spain . industrial crops and products, 2016, vol. 79, p. 18–28. DOI: 10.1016/j.indcrop.2015.10.009. [DOI link]

Language:

English (en)
Plant part:

Flowering top (as part-nature) (A166H)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-FID-MS (F607A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

30.57-54.09
Internal remarks:

1,8-cineole in essential oil

Composition #26: Carrasco, Alejandro., Tomas, Virginia., Tudela, Jose., Miguel, Maria G. Comparative study of GC-MS characterization, antioxidant activity and hyaluronidase inhibition of different species of Lavandula and Thymus essential oils . flavour and fragrance journal, 2016, vol. 31, no. 1, p. 57–69. DOI: 10.1002/ffj.3283. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

steam distillation
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

FGC-EI-MS
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

29.5-29.9
Internal remarks:

1,8-cineole in essential oil

Composition #27: Carrasco, Alejandro., Tomas, Virginia., Tudela, Jose., Miguel, Maria G. Comparative study of GC-MS characterization, antioxidant activity and hyaluronidase inhibition of different species of Lavandula and Thymus essential oils . flavour and fragrance journal, 2016, vol. 31, no. 1, p. 57–69. DOI: 10.1002/ffj.3283. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

steam distillation
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

FGC-EI-MS
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

11.4-11.8
Internal remarks:

camphor in essential oil

Composition #28: Guillen, MD., Cabo, N., Burillo, J. Characterisation of the essential oils of some cultivated aromatic plants of industrial interest . journal of the science of food and agriculture, 1996, vol. 70, no. 3, p. 359–363. DOI: 10.1002/(SICI)1097-0010(199603)70:3<359::AID-JSFA512>3.0.CO;2-0. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

steam distillation
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

31.31
Internal remarks:

1.8-cineol in essential oil

Composition #29: Guillen, MD., Cabo, N., Burillo, J. Characterisation of the essential oils of some cultivated aromatic plants of industrial interest . journal of the science of food and agriculture, 1996, vol. 70, no. 3, p. 359–363. DOI: 10.1002/(SICI)1097-0010(199603)70:3<359::AID-JSFA512>3.0.CO;2-0. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

steam distillation
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

13.6
Internal remarks:

camphor in essential oil