EFSA
ecomole
vscht
  2. Justicia adhatoda L. // Adhatoda vasica Nees

Justicia adhatoda L. // Adhatoda vasica Nees

Family:
Achanthaceae
Approval state:
Approved
Number of articles retrieved:
1206
Number of processed references:
8
Compositions
#1: Neoandrographolide in leaves #2: Vasicinone in leaves #3: Vasicine in leaves #4: 2-acetyl benzylamine (alkaloid) in leaves #5: Vasicine acetate in leaves #6: quinazoline alkaloids in roots #7: Peganine (=vasicine) in leaves, roots and flowers #8: quinazoline alkaloids in leaves #9: Vasicinol (a quinazoline alkaloid) in leaves #10: Cardiac Glycosides in plant #11: Alkaloids in plant #12: Saponins in plant #13: Phlobotannins in plant #14: Vasicinone in leaves #15: Vasicine in leaves
Endpoint Studies
#1: Decreased implantation in rats after extracts of J.adhatoda p.o. (review, no details/primary data) #2: Reproductive study in rat; resorption of all fetuses in 7 rats dosed with leaves (175 mg/kg bw daily for 10 days, day 0-9 of gestation) #3: Slight decrease in fetal body weight after treatment of pregnant rats #4: Dose dependent increase of resorptions after treatment of pregnant rats
Genotoxicity
Composition #1: Al-Amin, Md., Islam, Md. Monirul., Siddiqi, M. Mahboob Ali., Akter, Shakila., Ahmed, Shamim., Haque, Mohammad Majedul., Sultana, Nasim., Chowdhury, A. M. Sarwaruddin. Neoandrographolide isolated from leaves of Adhatoda vasica Nees. dhaka university journal of science, 2012, vol. 60, no. 1, p. 1–3. .
Composition #2: Singh Awantika., Kumar Sunil., Bajpai Vikas., Kumar Brijesh., Singh Awantika., Bajpai Vikas., Kumar Brijesh. Simultaneous determination of pyrroquinazoline alkaloids and flavonoids in Adhatoda beddomei and Adhatoda vasica and their marketed herbal formulations using ultra-high-performance liquid chromatography coupled with triple quadrupole linear ion trap mass spectrometry. biomedical chromatography : bmc, 2017, p. 31(3). .
Composition #3: Singh Awantika., Kumar Sunil., Bajpai Vikas., Kumar Brijesh., Singh Awantika., Bajpai Vikas., Kumar Brijesh. Simultaneous determination of pyrroquinazoline alkaloids and flavonoids in Adhatoda beddomei and Adhatoda vasica and their marketed herbal formulations using ultra-high-performance liquid chromatography coupled with triple quadrupole linear ion trap mass spectrometry. biomedical chromatography : bmc, 2017, p. 31(3). .
Composition #4: Paulraj, M. Gabriel., Shanmugam, N., Ignacimuthu, S. Antifeedant activity and toxicity of two alkaloids from Adhatoda vasica Nees leaves against diamondback moth Plutella xylostella (Linn.) (Lepidoptera: Plutellidae) larvae . archives of phytopathology and plant protection, 2014, vol. 47, no. 15, p. 1832–1840. DOI: 10.1080/03235408.2013.859402. [DOI link]
Composition #5: Paulraj, M. Gabriel., Shanmugam, N., Ignacimuthu, S. Antifeedant activity and toxicity of two alkaloids from Adhatoda vasica Nees leaves against diamondback moth Plutella xylostella (Linn.) (Lepidoptera: Plutellidae) larvae . archives of phytopathology and plant protection, 2014, vol. 47, no. 15, p. 1832–1840. DOI: 10.1080/03235408.2013.859402. [DOI link]
Composition #6: Claeson, UP., Malmfors, T., Wikman, G., Bruhn, JG. Adhatoda vasica: a critical review of ethnopharmacological and toxicological data . journal of ethnopharmacology, 2000, vol. 72, no. 1-2, p. 1–20. DOI: 10.1016/S0378-8741(00)00225-7. [DOI link]
Composition #7: Claeson, UP., Malmfors, T., Wikman, G., Bruhn, JG. Adhatoda vasica: a critical review of ethnopharmacological and toxicological data . journal of ethnopharmacology, 2000, vol. 72, no. 1-2, p. 1–20. DOI: 10.1016/S0378-8741(00)00225-7. [DOI link]
Composition #8: Claeson, UP., Malmfors, T., Wikman, G., Bruhn, JG. Adhatoda vasica: a critical review of ethnopharmacological and toxicological data . journal of ethnopharmacology, 2000, vol. 72, no. 1-2, p. 1–20. DOI: 10.1016/S0378-8741(00)00225-7. [DOI link]
Composition #9: Gao, Hong., Huang, Yi-Na., Gao, Bo., Li, Peng., Inagaki, Chika., Kawabata, Jun. Inhibitory effect on alpha-glucosidase by Adhatoda vasica Nees. food chemistry, 2008, vol. 108, no. 3, p. 965–972. DOI: 10.1016/j.foodchem.2007.12.002. [DOI link]
Composition #10: Khan, Amir Muhammad., Qureshi, Rizwana Aleem., Ullah, Faizan., Gilani, Syed Aneel., Nosheen, Asia., Sahreen, Sumaira., Laghari, Muhammad Khan., Laghari, Muhammad Yousif., Shafiq-Ur-Rehman., Hussain, Ishtiaq., Murad, Waheed. Phytochemical analysis of selected medicinal plants of Margalla Hills and surroundings . journal of medicinal plants research, 2011, vol. 5, no. 25, p. 6017–6023. DOI: 10.5897/JMPR11.869. [DOI link]
Composition #11: Khan, Amir Muhammad., Qureshi, Rizwana Aleem., Ullah, Faizan., Gilani, Syed Aneel., Nosheen, Asia., Sahreen, Sumaira., Laghari, Muhammad Khan., Laghari, Muhammad Yousif., Shafiq-Ur-Rehman., Hussain, Ishtiaq., Murad, Waheed. Phytochemical analysis of selected medicinal plants of Margalla Hills and surroundings . journal of medicinal plants research, 2011, vol. 5, no. 25, p. 6017–6023. DOI: 10.5897/JMPR11.869. [DOI link]
Composition #12: Khan, Amir Muhammad., Qureshi, Rizwana Aleem., Ullah, Faizan., Gilani, Syed Aneel., Nosheen, Asia., Sahreen, Sumaira., Laghari, Muhammad Khan., Laghari, Muhammad Yousif., Shafiq-Ur-Rehman., Hussain, Ishtiaq., Murad, Waheed. Phytochemical analysis of selected medicinal plants of Margalla Hills and surroundings . journal of medicinal plants research, 2011, vol. 5, no. 25, p. 6017–6023. DOI: 10.5897/JMPR11.869. [DOI link]
Composition #13: Khan, Amir Muhammad., Qureshi, Rizwana Aleem., Ullah, Faizan., Gilani, Syed Aneel., Nosheen, Asia., Sahreen, Sumaira., Laghari, Muhammad Khan., Laghari, Muhammad Yousif., Shafiq-Ur-Rehman., Hussain, Ishtiaq., Murad, Waheed. Phytochemical analysis of selected medicinal plants of Margalla Hills and surroundings . journal of medicinal plants research, 2011, vol. 5, no. 25, p. 6017–6023. DOI: 10.5897/JMPR11.869. [DOI link]
Composition #14: Burgos, R., Forcelledo, M., Wagner, H., Muller, A., Hancke, J., Wikman, G., Croxatto, H. Non-abortive effect of Adhatoda vasica spissum leaf extract by oral administration in rats . phytomedicine, 1997, vol. 4, no. 2, p. 145–149. .
Composition #15: Burgos, R., Forcelledo, M., Wagner, H., Muller, A., Hancke, J., Wikman, G., Croxatto, H. Non-abortive effect of Adhatoda vasica spissum leaf extract by oral administration in rats . phytomedicine, 1997, vol. 4, no. 2, p. 145–149. .
Endpoint study #1: Claeson, UP., Malmfors, T., Wikman, G., Bruhn, JG. Adhatoda vasica: a critical review of ethnopharmacological and toxicological data . journal of ethnopharmacology, 2000, vol. 72, no. 1-2, p. 1–20. DOI: 10.1016/S0378-8741(00)00225-7. [DOI link]
Endpoint study #2: NATH, D., SETHI, N., SINGH, RK., JAIN, AK. COMMONLY USED INDIAN ABORTIFACIENT PLANTS WITH SPECIAL REFERENCE TO THEIR TERATOLOGIC EFFECTS IN RATS . journal of ethnopharmacology, 1992, vol. 36, no. 2, p. 147–154. DOI: 10.1016/0378-8741(92)90015-J. [DOI link]
Endpoint study #3: Burgos, R., Forcelledo, M., Wagner, H., Muller, A., Hancke, J., Wikman, G., Croxatto, H. Non-abortive effect of Adhatoda vasica spissum leaf extract by oral administration in rats . phytomedicine, 1997, vol. 4, no. 2, p. 145–149. .
Endpoint study #4: Burgos, R., Forcelledo, M., Wagner, H., Muller, A., Hancke, J., Wikman, G., Croxatto, H. Non-abortive effect of Adhatoda vasica spissum leaf extract by oral administration in rats . phytomedicine, 1997, vol. 4, no. 2, p. 145–149. .