Draft - work in progress
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- Hypericum maculatum Crantz
Hypericum maculatum Crantz
- Family:
- Hypericaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 166
- Number of processed references:
- 7
Composition #1: Polezhaeva, N. S., Kanyuchkova, G. K. Content of flavonoids, tannins, and carotenoids in Hypericum maculatum Crantz. rastitel'nye resursy, 1985, vol. 21, no. 3, p. 340–3. .
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Substance:
Tannins (RF-00004337-PAR)
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Analytical method code:
Unspecified (F598A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
12.1-13.52
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Internal remarks:
Tannins (12.1-13.52%) during early-to mid-flowering in aerial parts
Composition #2: Girzu-Amblard, M., Carnat, A., Fraisse, D., Carnat, A.-P., Lamaison, J.-L. Flavonoid and dianthranoid levels of the St.-John's-wort flowering tops. annales pharmaceutiques francaises, 2000, vol. 58, no. 5, p. 341–345. .
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Plant part:
Flowering top (as part-nature) (A166H)
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Substance:
hypericin (RF-00003434-PAR)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
0.02
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Internal remarks:
0.02% hypericin in the flowering tops
Composition #3: Girzu-Amblard, M., Carnat, A., Fraisse, D., Carnat, A.-P., Lamaison, J.-L. Flavonoid and dianthranoid levels of the St.-John's-wort flowering tops. annales pharmaceutiques francaises, 2000, vol. 58, no. 5, p. 341–345. .
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Plant part:
Flowering top (as part-nature) (A166H)
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Substance:
pseudohypericin (RF-00003558-PAR)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
0.11
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Internal remarks:
0.11 pseudohypericin in the flowering tops
Composition #4: Smelcerovic, Andrija., Spiteller, Michael., Ligon, Axel Patrick., Smelcerovic, Zaklina., Raabe, Nils. Essential oil composition of Hypericum L. species from Southeastern Serbia and their chemotaxonomy . biochemical systematics and ecology, 2007, vol. 35, no. 2, p. 99–113. DOI: 10.1016/j.bse.2006.09.012.
[
DOI link]
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Additional extraction description:
Steam distillation
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Substance:
(-)-globulol (RF-00003756-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
0.1-8.0
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Internal remarks:
Globulol in essential oil of aerial parts
Composition #5: Kusari, Souvik., Zuehlke, Sebastian., Borsch, Thomas., Spiteller, Michael. Positive correlations between hypericin and putative precursors detected in the quantitative secondary metabolite spectrum of Hypericum . phytochemistry, 2009, vol. 70, no. 10, p. 1222–1232. DOI: 10.1016/j.phytochem.2009.07.022.
[
DOI link]
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
50 ml MeOH: CHCl3 (80:20) AND aqueous
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Substance:
hypericin (RF-00003434-PAR)
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Additional substance description:
Leaves AND Stems
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Analytical method code:
LC-MS/MS (F027A)
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Result unit:
Microgram/gram (G049A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
3-84
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Internal remarks:
Hypericin in leaves and stems
Composition #6: Kusari, Souvik., Zuehlke, Sebastian., Borsch, Thomas., Spiteller, Michael. Positive correlations between hypericin and putative precursors detected in the quantitative secondary metabolite spectrum of Hypericum . phytochemistry, 2009, vol. 70, no. 10, p. 1222–1232. DOI: 10.1016/j.phytochem.2009.07.022.
[
DOI link]
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Plant part:
Live plants (as part-nature) (A0BA0)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
50 ml MeOH: CHCl3 (80:20) AND aqueous
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Substance:
hyperforin (RF-00003433-PAR)
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Additional substance description:
Roots, Leaves AND Stems
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Analytical method code:
LC-MS/MS (F027A)
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Result unit:
Microgram/gram (G049A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
266-2449
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Internal remarks:
Hyperforin in roots, leaves and stems
Composition #7: Kusari, Souvik., Zuehlke, Sebastian., Borsch, Thomas., Spiteller, Michael. Positive correlations between hypericin and putative precursors detected in the quantitative secondary metabolite spectrum of Hypericum . phytochemistry, 2009, vol. 70, no. 10, p. 1222–1232. DOI: 10.1016/j.phytochem.2009.07.022.
[
DOI link]
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
50 ml MeOH: CHCl3 (80:20) AND aqueous
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Substance:
pseudohypericin (RF-00003558-PAR)
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Additional substance description:
Leaves AND Stems
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Analytical method code:
LC-MS/MS (F027A)
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Result unit:
Microgram/gram (G049A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
17-318
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Internal remarks:
Pseudohypericin in leaves and stems
Composition #8: Kusari, Souvik., Zuehlke, Sebastian., Borsch, Thomas., Spiteller, Michael. Positive correlations between hypericin and putative precursors detected in the quantitative secondary metabolite spectrum of Hypericum . phytochemistry, 2009, vol. 70, no. 10, p. 1222–1232. DOI: 10.1016/j.phytochem.2009.07.022.
[
DOI link]
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
50 ml MeOH: CHCl3 (80:20) AND aqueous
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Substance:
Emodin (RF-00003798-PAR)
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Analytical method code:
LC-MS/MS (F027A)
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Result unit:
Microgram/gram (G049A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
0.3
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Internal remarks:
Emodin in leaves
Composition #9: Nedialkov, Paraskev T., Momekov, Georgi., Kokanova-Nedialkova, Zlatina K., Heilmann, Joerg. Polyprenylated Phloroglucinols from Hypericum maculatum. natural product communications, 2015, vol. 10, no. 7, p. 1231–1235. .
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
dichloromethane
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Substance:
phloroglucinol derivatives (RF-00004380-PAR)
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Additional substance description:
Maculatoquiones A, B, C, D, and Erectquione A, Hyperibine J, and four other polyprenylated phloroglucinol derivatives without common names
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Analytical method code:
Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
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Analytical method - additional description:
Also: NMR, MS, IR, UV
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Polyprenylated phloroglucinol derivatives (Maculatoquiones A, B, C, D, and Erectquione A, Hyperibine J, and four other polyprenylated phloroglucinol derivatives without common names) in aerial parts
Composition #10: Oniga, Ilioara., Toiu, Anca., Benedec, Daniela., Tomuta, Ioan., Vlase, Laurian. PHYTOCHEMICAL ANALYSIS OF HYPERICUM MACULATUM IN ORDER TO OBTAIN STANDARDIZED EXTRACTS . farmacia, 2016, vol. 64, no. 2, p. 171–174. .
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
methanol or ethanol
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Substance:
Isoquercitrin (RF-00010712-PAR)
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Analytical method code:
LC-MS (F026A)
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Analytical method - additional description:
HPLC-MSD-Ion Trap
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Result unit:
Milligram/100 gram (G057A)
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Result expression:
Whole weight (B001A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
244.59
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Internal remarks:
Isoquercitrin in aerial parts
Composition #11: Oniga, Ilioara., Toiu, Anca., Benedec, Daniela., Tomuta, Ioan., Vlase, Laurian. PHYTOCHEMICAL ANALYSIS OF HYPERICUM MACULATUM IN ORDER TO OBTAIN STANDARDIZED EXTRACTS . farmacia, 2016, vol. 64, no. 2, p. 171–174. .
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
methanol or ethanol
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Substance:
hypericin (RF-00003434-PAR)
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Additional substance description:
"Total Hypericins"
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Analytical method code:
LC-MS (F026A)
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Analytical method - additional description:
HPLC-MSD-Ion Trap
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Result unit:
Gram/100 gram (G013A)
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Result expression:
Whole weight (B001A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
0.12-0.74
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Internal remarks:
Total Hypericins in aerial parts
Composition #12: Rusalepp, Linda., Raal, Ain., Puessa, Tonu., Maeeorg, Uno. Comparison of chemical composition of Hypericum perforatum and H-maculatum in Estonia . biochemical systematics and ecology, 2017, vol. 73, p. 41–46. DOI: 10.1016/j.bse.2017.06.004.
[
DOI link]
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
methanol
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Substance:
hypericin (RF-00003434-PAR)
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Analytical method code:
HPLC-DAD (F587A)
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Analytical method - additional description:
HPLC-DAD-MS/MS
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
0.07-0.15
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Internal remarks:
Hypericin in aerial parts
Composition #13: Rusalepp, Linda., Raal, Ain., Puessa, Tonu., Maeeorg, Uno. Comparison of chemical composition of Hypericum perforatum and H-maculatum in Estonia . biochemical systematics and ecology, 2017, vol. 73, p. 41–46. DOI: 10.1016/j.bse.2017.06.004.
[
DOI link]
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
methanol
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Substance:
Isoquercitrin (RF-00010712-PAR)
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Analytical method code:
HPLC-DAD (F587A)
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Analytical method - additional description:
HPLC-DAD-MS/MS
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
0.87-0.88
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Internal remarks:
Isoquercitrin in aerial parts
Composition #14: Rusalepp, Linda., Raal, Ain., Puessa, Tonu., Maeeorg, Uno. Comparison of chemical composition of Hypericum perforatum and H-maculatum in Estonia . biochemical systematics and ecology, 2017, vol. 73, p. 41–46. DOI: 10.1016/j.bse.2017.06.004.
[
DOI link]
-
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
methanol
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Substance:
pseudohypericin (RF-00003558-PAR)
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Additional substance description:
Also, the related compound: Protopseudohypericin 0.02-0.45%
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Analytical method code:
HPLC-DAD (F587A)
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Analytical method - additional description:
HPLC-DAD-MS/MS
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
0.16-0.19
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Internal remarks:
Pseudohypericin and Protopseudohypericin in aerial parts
Composition #15: Rusalepp, Linda., Raal, Ain., Puessa, Tonu., Maeeorg, Uno. Comparison of chemical composition of Hypericum perforatum and H-maculatum in Estonia . biochemical systematics and ecology, 2017, vol. 73, p. 41–46. DOI: 10.1016/j.bse.2017.06.004.
[
DOI link]
-
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
methanol
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Substance:
hyperforin (RF-00003433-PAR)
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Additional substance description:
Also, the related compound: adhyperforin 0.05-0.11%
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Analytical method code:
HPLC-DAD (F587A)
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Analytical method - additional description:
HPLC-DAD-MS/MS
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
0.13-0.49
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Internal remarks:
Hyperforin and Adhyperforin in aerial parts