EFSA
ecomole
vscht
  2. Hedera helix L.

Hedera helix L.

Family:
Araliaceae
Approval state:
Approved
Number of articles retrieved:
1836
Number of processed references:
6
Compositions
#1: Druse crystals (Calcium oxalates in stem/leaves) #2: Triterpene saponins (hederacoside C and alpha-hederine) in leaves and fruits #3: Saponins derivatives: bellisdeacylsaponins, bellissaponin (BS1/BS2) and hederasaponins (dried and ground herbs) #4: Hederacoside C (dried leaf) #5: Hederasaponin B (dried leaf) #6: beta-hederin (Stem/phloem) #7: saponins (dried leaves)
Endpoint Studies
#1: burning sensation in the mouth, hypersalivation, nausea, vomiting, abdominal pain and diarrhea
Genotoxicity
Composition #1: Tutuncu Konyar, Sevil., Ozturk, Necla., Dane, Feruzan. Occurrence, types and distribution of calcium oxalate crystals in leaves and stems of some species of poisonous plants. botanical studies, 2014, vol. 55, no. 1, p. 1–9. .
Composition #2: Busser, C. Toxic berries, fruits and pseudo-fruits in traditional medicine and phytotherapy . phytotherapie (paris), 2007, vol. 5, no. 1, p. 31–36. DOI: 10.1007/s10298-007-0205-y. [DOI link]
Composition #3: Walthelm, U., Dittrich, K., Gelbrich, G., Schopke, T. Effects of saponins on the water solubility of different model compounds. planta medica, 2001, vol. 67, no. 1, p. 49–54. DOI: 10.1055/s-2001-10876. [DOI link]
Composition #4: Yu, Miao., Shin, Young June., Kim, Nanyoung., Yoo, Guijae., Park, SeonJu., Kim, Seung Hyun. Determination of Saponins and Flavonoids in Ivy Leaf Extracts Using HPLC-DAD . journal of chromatographic science, 2015, vol. 53, no. 4, p. 478–483. DOI: 10.1093/chromsci/bmu068. [DOI link]
Composition #5: Yu, Miao., Shin, Young June., Kim, Nanyoung., Yoo, Guijae., Park, SeonJu., Kim, Seung Hyun. Determination of Saponins and Flavonoids in Ivy Leaf Extracts Using HPLC-DAD . journal of chromatographic science, 2015, vol. 53, no. 4, p. 478–483. DOI: 10.1093/chromsci/bmu068. [DOI link]
Composition #6: Himmelsbach, Markus., Weth, Agnes., Boehme, Christine., Schwarz, Martin., Braeunig, Peter., Baumgartner, Werner. The plant hopper Issus coleoptratus can detoxify phloem sap saponins including the degradation of the terpene core . biology open, 2016, vol. 5, no. 3, p. 252–255. DOI: 10.1242/bio.016311. [DOI link]
Composition #7: ELIAS, R., DEMEO, M., VIDALOLLIVIER, E., LAGET, M., BALANSARD, G., DUMENIL, G. ANTIMUTAGENIC ACTIVITY OF SOME SAPONINS ISOLATED FROM CALENDULA-OFFICINALIS L, CALENDULA-ARVENSIS L AND HEDERA-HELIX L . mutagenesis, 1990, vol. 5, no. 4, p. 327–331. DOI: 10.1093/mutage/5.4.327. [DOI link]
Endpoint study #1: Busser, C. Toxic berries, fruits and pseudo-fruits in traditional medicine and phytotherapy . phytotherapie (paris), 2007, vol. 5, no. 1, p. 31–36. DOI: 10.1007/s10298-007-0205-y. [DOI link]